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    METHOD AND APPARATUS TO PROVIDE PARALLEL ACQUISITION OF MASS SPECTROMETRY/MASS SPECTROMETRY DATA
    2.
    发明公开
    METHOD AND APPARATUS TO PROVIDE PARALLEL ACQUISITION OF MASS SPECTROMETRY/MASS SPECTROMETRY DATA 审中-公开
    方法和装置，提供质量/质量数据的并行采集

    公开(公告)号：EP2831904A2

    公开(公告)日：2015-02-04

    申请号：EP13713623.0

    申请日：2013-03-13

    申请人： Ulvac-Phi, Inc. ,  Heeren, Ron M.

    发明人： LARSON, Paul, E. ,  HAMMOND, John, S. ,  FISHER, Gregory, L. ,  HEEREN, Ron, M.

    IPC分类号： H01J49/00 ,  H01J49/06

    CPC分类号： H01J49/004 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0045 ,  H01J49/009 ,  H01J49/061 ,  H01J49/142 ,  H01J49/40

    摘要： A system and method for acquisition of mass spectrometry data is configured to provide a stream of charged particles (e.g., from an analytical volume). A primary mass spectrometer (e.g., time-of-flight mass spectrometer) may be used to separate charged particles of the stream of charged particles based on their mass-to-charge ratio and detect the charged particles in a mass-to-charge spectrum. A stream of precursor ions having a selected mass range may be diverted from the stream of charged particles for fragmentation to provide fragment ions (e.g., fragment ions from the analytical volume). The fragment ions may be provided to a second mass spectrometer for analysis of the fragment ions (e.g., during the same time as the time-of-flight mass spectrometer is separating and detecting charged particles of the stream of charged particles based on their mass-to-charge ratio).

    摘要翻译： 一种用于获取质谱数据的系统和方法被配置成提供带电粒子（体积E. G.，来自分析）的流。 初级质谱仪（例如，飞行时间型质谱仪）可以被用来在质量 - 电荷光谱分离带电粒子的基于它们的质荷比的流的带电粒子和检测带电粒子 ， 具有选择的质量范围的前体离子的流可以从带电粒子的流被转向为碎片，以提供碎片离子（例如，从分析体积碎片离子）。 碎片离子可以被提供给第二质谱仪的碎片离子的分析（例如，在相同的时间作为时间飞行质谱仪分离和检测基于其量身定带电的带电粒子流的粒子 荷比）。

    PARALLEL MASS ANALYSIS
    6.
    发明公开
    PARALLEL MASS ANALYSIS 审中-公开
    平行MASSENANALYSE

    公开(公告)号：EP2108185A2

    公开(公告)日：2009-10-14

    申请号：EP07866268.1

    申请日：2007-12-27

    申请人： Thermo Fisher Scientific (Bremen) GmbH

    发明人： MAKAROV, Alexander Alekseevich ,  HORNING, Stevan Roy

    IPC分类号： H01J49/00 ,  H01J49/42

    CPC分类号： H01J49/009 ,  H01J49/425

    摘要： A system and method of mass spectrometry is provided. Ions from an ion source are stored in a first ion storage device and in a second ion storage device. Ions are ejected from the first ion storage device to a first mass analysis device during a first ejection time period, for analysis during a first analysis time period. Ions are ejected from the second ion storage device to a second mass analysis device during a second ejection time period. The ion storage devices are connected in series such that an ion transport aperture of the first ion storage device is in communication with an ion transport aperture of the second ion storage device. The first analysis time period and the second ejection time period at least partly overlap.

    ION PROCESSING: STORAGE, COOLING AND SPECTROMETRY
    8.
    发明授权
    ION PROCESSING: STORAGE, COOLING AND SPECTROMETRY 失效
    离子处理：存储和冷却光谱

    公开(公告)号：EP0524311B1

    公开(公告)日：1996-05-08

    申请号：EP92907401.1

    申请日：1992-02-11

    申请人： KIRCHNER, Nicholas J.

    发明人： KIRCHNER, Nicholas J.

    IPC分类号： H01J49/34

    CPC分类号： H01J49/4235 ,  G21K1/003 ,  H01J49/009 ,  H01J49/065 ,  H01J49/34

    摘要： An ion processing unit (10), including a series of M perforated electrode sheets (12), driving electronics (14, 16) and a central processing unit (18), allows formation, shaping and translation of multiple effective potential wells (42). Ions, trapped within a given effective potential well (42), can be isolated, transferred, cooled or heated, separated, and combined. Measurement of induced image currents allows measurement and typing of ion species by their respective charge-to-mass ratios. The combination of many electrode sheets (12), each having N multiple perforations (22), creates a plurality of parallel ion processing channels (26). The ion processing unit (10) provides an N by M massively parallel ion processing system, furnishing means for processing large numbers of ions in parallel in the same manner, but with different ion processes deployed at different sections of each ion processing channel (26). In addition, the space-filling parallel structure of the present invention provides an efficient means for temporary storage of large numbers of ions, including charged antimatter.

    ION INTERFACE DEVICE HAVING MULTIPLE CONFINEMENT CELLS AND METHODS OF USE THEREOF
    9.
    发明授权
    ION INTERFACE DEVICE HAVING MULTIPLE CONFINEMENT CELLS AND METHODS OF USE THEREOF 有权
    具有多个约束单元的离子接口装置及其使用方法

    公开(公告)号：EP2774168B1

    公开(公告)日：2017-09-20

    申请号：EP12790742.6

    申请日：2012-11-01

    申请人： Thermo Finnigan LLC

    发明人： KOVTOUN, Viatcheslav, V.

    IPC分类号： H01J49/00 ,  H01J49/04

    CPC分类号： H01J49/0045 ,  H01J49/009 ,  H01J49/0481 ,  H01J49/06 ,  H01J49/4295

    摘要： A device and associated method are disclosed for interfacing an ion trap to a pulsed mass analyzer (such as a time-of-flight analyzer) in a mass spectrometer. The device includes a plurality of separate confinement cells and structures for directing ions into a selected one of the confinement cells. Ions are ejected from the ion trap in a series of temporally successive ion packets. Each ion packet (which may consist of ions of like mass-to-charge ratio), is received by the ion interface device, fragmented to form product ions, and then stored and cooled in the selected confinement cell. Storage and cooling of the ion packet occurs concurrently with the receipt and storage of at least one later-ejected ion packet. After a predetermined cooling period, the ion packet is released to the mass analyzer for acquisition of a mass spectrum.

    摘要翻译： 公开了一种用于将离子阱与质谱仪中的脉冲质量分析仪（例如飞行时间分析仪）接口连接的装置和相关方法。 该装置包括多个单独的约束单元和用于将离子引导到约束单元中选定的一个中的结构。 离子通过一系列时间连续的离子包从离子阱中喷出。 每个离子包（其可由类似质荷比的离子组成）被离子界面装置接收，分裂以形成产物离子，然后在选定的限制室中储存和冷却。 离子包的存储和冷却与接收和存储至少一个后来喷射的离子包同时发生。 在预定的冷却时间之后，离子包被释放到质量分析器以获取质谱。

    MASS SPECTROMETRY METHOD AND DEVICES
    10.
    发明公开
    MASS SPECTROMETRY METHOD AND DEVICES 审中-公开
    MASSENSPEKTROMETRIEVERFAHREN UND -VORRICHTUNG

    公开(公告)号：EP2958133A1

    公开(公告)日：2015-12-23

    申请号：EP13875207.6

    申请日：2013-03-13

    申请人： Saparqaliyev, Aldan Asanovich

    发明人： Saparqaliyev, Aldan Asanovich

    IPC分类号： H01J49/40 ,  G01N30/72

    CPC分类号： G01N30/72 ,  H01J49/009 ,  H01J49/405 ,  H01J49/406

    摘要： This invention relates to the analytical electronics used to identify compositions and structures of substances, in particular, to the analyzers comprising at least one mass-spectrometer (MS) and may be applied in such fields as medicine, biology, gas and oil industry, metallurgy, energy, geochemistry, hydrology, ecology.
    Technical result provides the increase in MS resolution capacity, gain in sensitivity, precision and measurement rates of substances compositions and structures concurrently with enhancement of analyzer functional capabilities, downsizing and mass reduction.
    A multipath method of mass-spectrometry and a three-dimensional reflecting (-reflecting) method of mass-spectrometry requiring to use a three-dimensional reflecting IO sub-system (- reflector) are developed. A new type of electric field distribution such as transversely discontinuous conic field distribution, including its type of three-dimensional distribution in area of reflection, is proposed to implementing said methods.
    Versions of devices to implement the claimed method are developed.
    Proposed schematic ion optical diagrams allow to developing different MS types.

    摘要翻译： 本发明涉及用于识别物质的组成和结构的分析电子装置，特别涉及包含至少一种质谱仪（MS）的分析仪，并且可以应用于诸如医药，生物学，燃气和石油工业，冶金学 ，能源，地球化学，水文学，生态学。 技术结果提高了分析能力，提高了分析仪功能，缩小尺寸和减少质量的同时，提高了MS分辨率，灵敏度，精度和物质成分和结构测量速率。 开发了质谱法的多路径法和需要使用三维反射IO子系统（ - 反射器）的质谱法的三维反射（ - 反射）方法。 提出了一种新型的电场分布，如横向不连续圆锥场分布，包括其反射区域的三维分布类型，用于实现所述方法。 开发了实现所要求保护的方法的设备的版本。 拟议的示意图光学图允许开发不同的MS类型。