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    DRUG FORMULATION CONTAINING SEPETAPROST
    7.
    发明公开
    DRUG FORMULATION CONTAINING SEPETAPROST 审中-公开

    公开(公告)号：EP4197540A1

    公开(公告)日：2023-06-21

    申请号：EP21855988.8

    申请日：2021-08-12

    申请人： Santen Pharmaceutical Co., Ltd.

    发明人： YAMAMOTO Yasuko ,  TANIGUCHI Takazumi ,  SHIMAZAKI Atsushi ,  KIMURA Erika

    IPC分类号： A61K31/558 ,  A61K45/00 ,  A61P27/06

    摘要： The purpose of the present invention is to identify a drug formulation for the treatment or prevention of glaucoma or ocular hypertension, wherein the drug formulation exhibits an effect in patients with drug-refractory glaucoma or ocular hypertension. Sepetaprost is expected to exhibit an excellent intraocular pressure-lowering action in patients with otherwise drug-refractory glaucoma or ocular hypertension. The drug formulation according to the present invention containing sepetaprost as an active ingredient is therefore useful as a drug formulation that can treat or prevent glaucoma or ocular hypertension in patients with otherwise drug-refractory glaucoma or ocular hypertension.

    ORAL FILM PREPARATION
    8.
    发明公开
    ORAL FILM PREPARATION 审中-公开
    口服胶囊准备

    公开(公告)号：EP3281625A1

    公开(公告)日：2018-02-14

    申请号：EP16776569.2

    申请日：2016-04-06

    申请人： Nipro Corporation

    发明人： KAWAMURA, Naohisa ,  SHINKAI, Norihiro ,  SHIRAISHI, Hiroaki ,  TSUDA, Yo

    IPC分类号： A61K9/70 ,  A61K31/343 ,  A61K31/4164 ,  A61K31/485 ,  A61K31/5575 ,  A61K31/558 ,  A61K31/59 ,  A61K47/10 ,  A61K47/14 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/40 ,  A61K47/42 ,  A61K47/46 ,  A61P17/04

    摘要： The present invention relates to an oral film preparation obtained by spreading a solution containing a high potency drug and a film-forming polymer and then drying the solution, and a method for preparing an oral film preparation containing a high potency drug, said method comprising spreading a solution containing the high potency drug and a film-forming polymer and then drying the same, and a package obtained by (a) packaging the oral film preparation in a packaging material and, after nitrogen substitution, sealing the packaging material, and/or (b) sealing the oral film preparation together with a deoxidant in a packaging material. Provided are an oral film preparation that contains a high potency drug and has excellent content uniformity, a method for easily preparing an oral film preparation that contains a high potency drug and has excellent content uniformity, and a highly stable package that contains the oral film preparation.

    摘要翻译： 本发明涉及口服薄膜制剂，其是通过将含有高效药物和成膜聚合物的溶液涂布然后干燥该溶液而获得的口腔薄膜制剂，以及制备含有高效药物的口腔膜制剂的方法，所述方法包括将 含有高效药物和成膜聚合物的溶液，然后将其干燥，以及通过（a）将口腔膜制剂包装在包装材料中并在氮气置换后密封包装材料和/或 （b）将口腔膜制剂与脱氧剂一起密封在包装材料中。 本发明提供一种口服膜制剂，其含有高效力药物且含量均匀性优异，易于制备含有高效力药物且内容物均匀性优异的口腔内膜制剂的方法以及含有口腔内膜制剂 。