摘要:
A novel fluorine-containing acrylic acid derivative of the invention is represented by the formula:
wherein A is a residue derived from an organic compound having at least two active hydrogen atoms by removing at least two active hydrogen atoms, and p is an integer corresponding to the valency of the residue A, which is easily cured. Polymers comprising repeating units derived from the said acid derivative are also disclosed.
摘要:
Zur Reinigung von Methacrylamidopropyltrimethylam moniumchlorid oder ähnlichen quaternierten Aminoalkyl estern oder Aminoalkyamiden der Acryl- oder Methacrylsä ure von Verunreinigungen, die durch Hofmann'schen Abbau der genannten Verbindungen entstehen können, wie zB Allylmethacrylamid, wird eine wäßrige Lösung der Verbin dung mit Dichlormethan extrahiert.
摘要:
Zur Reinigung von Methacrylamidopropyltrimethylammoniumchlorid oder ähnlichen quaternierten Aminoalkylestern oder Aminoalkylamiden der Acryl- oder Methacrylsäure von Verunreinigungen, die durch Hofmann'schen Abbau der genannten Verbindungen entstehen können, wie z.B. Allylmethacrylamid, wird eine wäßrige Lösung der Verbindung mit Dichlormethan extrahiert.
摘要:
Novel liquid polyamides of formula RCONH(CH 2 CH 2 NH) n -OCR where R is alkyl or alkenyl with 10 to 22 carbon atoms and n is an integer in the range 1 to 4 may be used in compositions to reduce fouling on heat exchange surfaces.
摘要:
N-(aminomethyl)-α,β-ethytenically unsaturated cationic carboxamides such as N-(dimethylaminomethyl)-acrylamide are readily prepared without coincident production of saturated impurities by reacting an α,β-ethylenically unsaturated carboxamide such as acrylamide with a lower aldehyde such as formaldehyde and a secondary amine such as dimethylamine at a pH below 7. The resulting aminomethyl carboxamides are polymerized at a pH of 7 or less to form polymers containing essentially no gelled product. The resulting aminomethyl carboxamides can also be quatemized by reacting them with a quaternizing agent at a pH below 7. This quaternized products can be polymerized. The polymerisation products are flocculants.
摘要:
Compounds that selectively bind 5-HT 1A receptors in preference to other 5-HT receptors are provided along with methods for their use. Such compounds have the formula wherein A is an aromatic group selected to provide, with the glycidyl residue that forms the next portion of the molecule, a 5-HT-like portion of the molecule that represents the primary binding site of the molecule with a 5-HT receptor; X represents a quarternary carbon and its attached alkyl groups; Y represents a hydrocarbon linking group; Z represents hydrogen or an organic group containing up to 12 carbon and/or heteroatoms in its skeletal structure; and R¹ and R² independently represent hydrogen or an alkyl group. The aromatic group is most preferably indole or an indole derivative.
摘要:
Compounds of the formula wherein R1 is lower alkyl, lower cycloalkyl, lower alkenyl, lower alkynyl, lower alkyl carboxymethyl, aryl carboxymethyl, aryl, or aralkyl; A is a direct bond, lower alkylene, or lower alkenylene; x is 1 or 2, provided that when x is greater than 1, different occurences of the R1-O-C-A- group may be the same or different; Ar is heterocyclic, unsubstituted aromatic or aromatic substituted with lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, halogen, acetamido, amino, nitro, lower alkylamino, hydroxy, lower hydroxyalkyl or cyano; W is alkylene containing from 1 to about 10 carbon atoms; and B is -NR2COR3, -NR2CONR3R4, -NR2SO2R3, -NR2SO2NR3R4, or -NR2COOR5, wherein R2, R3, R4 and R5 may be the same or different and may be hydrogen, alkyl, alkoxyalkyl, alkoxyaryl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, or aralkyl, except that R3 and R5 are not hydrogen when B is -NR2SO2R3 or -NR2COOR5, or R3 and R4 may together with N form a 5 to 7 membered heterocyclic group; and the pharmaceutically acceptable salts thereof. The compounds of the present invention are beta -adrenergic blocking agents useful in the treatment of cardiac disorders, glaucoma, or the lowering of elevated intraocular pressure.