Arylsulfone compounds
    3.
    发明公开
    Arylsulfone compounds 失效
    ARYLSULFONE化合物

    公开(公告)号:EP0194669A3

    公开(公告)日:1988-01-27

    申请号:EP86103312

    申请日:1986-03-12

    摘要: A novel sulfone compound represented by the general formula (II)
    wherein R' is cyclohexyl, phenyL; or a phenyl substituted with a group selected from nitro, C 1 -C 3 alkyl, C 1- C 3 alkoxy and halogen; R 2 , R 3 , R 4 and R 5 are respectively hydrogen, halogen, cyano or carbonyl, wherein R' and R 2 may form an o-phenylene or an o-phenylene substituted with at least one group selected from nitro C 1 -C 3 alkyl, C 1 -C 3 alkoxy and halogen; X is oxygen or methylene; Y is -(CH 2 ) n -, wherein n is an integer of 0, 5 or 6, or
    wherein m is an integer 1-3; R 6 is hydrogen, C 1 -C 3 alkyl, ω-alkylaminoalkykl, wherein each alkyl has 1-3 carbon atoms, or ω-dialkylaminoalkyl, wherein each alkyl has 1-3 carbon atoms; R 7 is hydrogen: or C 1 -C 3 . alkyl; and R 6 and R 7 may farm 5 ring together with N, or
    wheren R B is hydrogen, C 1 -C 3 hydroxyalkyl or phenyl; or a pharmaceutically acceptable salt thereof is disclosed. The compound has anti-ulcer effect.