METHOD FOR THE IMMOBILIZATION OF OLIGONUCLEOTIDES
    5.
    发明公开
    METHOD FOR THE IMMOBILIZATION OF OLIGONUCLEOTIDES 审中-公开
    方法,进行固定的寡核苷酸

    公开(公告)号:EP1155056A1

    公开(公告)日:2001-11-21

    申请号:EP99960649.4

    申请日:1999-12-03

    CPC分类号: C12N15/87

    摘要: Novel compositions are provided for introducing into a cell, a nucleic acid molecule capable of modulating the genotype and phenotype. The gene can be introduced into a mammalian host by way of an expression vector either as naked DNA or conjugated to carriers, particularly cationic carriers. The conjugation is accomplished by means of an ethylene-containing moiety tethered to the nucleic acid molecule. The techniques and compositions find use in the palliation or treatment of any of a variety of genetic-based disorders.