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    INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF
    5.
    发明公开
    INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF 审中-公开
    具有改进的活性谱的杀虫多肽及其用途

    公开(公告)号：EP3207050A1

    公开(公告)日：2017-08-23

    申请号：EP15850317.7

    申请日：2015-10-14

    申请人： Pioneer Hi-Bred International, Inc.

    发明人： WILLCOXON, Michi Izumi ,  YAMAMOTO, Takashi

    IPC分类号： C07K14/325 ,  C12N15/32

    CPC分类号： C07K14/325 ,  A01N37/46 ,  A01N63/02 ,  A01N65/22 ,  A01N65/44 ,  C12N15/8286 ,  Y02A40/162 ,  A01N57/16

    摘要： The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

    摘要翻译： 本公开内容提供了源自苏云金芽孢杆菌菌株的编码变体多肽的核酸及其变体和片段，所述变体多肽对昆虫害虫（包括鳞翅目和鞘翅目）具有增加的杀虫活性。 本公开的具体实施方案提供了编码杀虫蛋白的分离的核酸，杀虫组合物，DNA构建体和包含所述实施方案的核酸的转化的微生物和植物。 这些组合物可用于防治害虫特别是植物害虫的方法中。

    AXMI221Z, AXMI222Z, AXMI223Z, AXMI224Z, AND AXMI225Z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE
    6.
    发明公开
    AXMI221Z, AXMI222Z, AXMI223Z, AXMI224Z, AND AXMI225Z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE 有权
    AXMI221Z-，AXMI222Z-，AXMI223Z-，AXMI224Z- UND AXMI225Z-DELTA-ENDOTOXIN-GENE UND VERFAHREN ZU DEREN VERWENDUNG

    公开(公告)号：EP2937419A3

    公开(公告)日：2016-01-20

    申请号：EP15171477.1

    申请日：2011-02-17

    申请人： Athenix Corp.

    发明人： Sampson, Kimberly S. ,  Tomso, Daniel John

    IPC分类号： C12N15/32 ,  C12N5/14 ,  C12N1/20 ,  A01H5/00 ,  C07K14/325 ,  A01N37/46 ,  A01N63/02 ,  C12N15/82

    CPC分类号： C12N15/8286 ,  A01N37/46 ,  A01N63/02 ,  C07K14/325 ,  C07K16/1278 ,  C12N15/8279 ,  Y02A40/162

    摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 27, 28, 23, 21, 22, 24-26 and 29-32, or the nucleotide sequence set forth in SEQ ID NO: 3, 8, 13, 18, 1, 2, 4-7, 9-12, 14-17, 19 and 20, as well as variants and fragments thereof.

    摘要翻译： 提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。 提供了包含毒素多肽的编码序列的组合物。 编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。 组合物还包括转化的细菌，植物，植物细胞，组织和种子。 特别地，提供了分离的毒素核酸分子。 另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。 特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：27,28,23,21,22,24-26和29-32所示氨基酸序列的核苷酸序列，或所述核苷酸序列 在SEQ ID NO：3,8,13,18，1,2,4-7,9-12,14-17,19和20中，以及其变体和片段。

    AXMI221Z, AXMI222Z, AXMI223Z, AXMI224Z, AND AXMI225Z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE
    7.
    发明公开
    AXMI221Z, AXMI222Z, AXMI223Z, AXMI224Z, AND AXMI225Z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE 有权
    AXMI221Z-，AXMI222Z-，AXMI223Z-，AXMI224Z-和AXMI225Z-δ-内毒素基因和它们的使用方法

    公开(公告)号：EP2937419A2

    公开(公告)日：2015-10-28

    申请号：EP15171477.1

    申请日：2011-02-17

    申请人： Athenix Corp.

    发明人： Sampson, Kimberly S. ,  Tomso, Daniel John

    IPC分类号： C12N15/32 ,  C12N5/14 ,  C12N1/20 ,  A01H5/00 ,  C07K14/325 ,  A01N37/46 ,  A01N63/02 ,  C12N15/82

    CPC分类号： C12N15/8286 ,  A01N37/46 ,  A01N63/02 ,  C07K14/325 ,  C07K16/1278 ,  C12N15/8279 ,  Y02A40/162

    摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 27, 28, 23, 21, 22, 24-26 and 29-32, or the nucleotide sequence set forth in SEQ ID NO: 3, 8, 13, 18, 1, 2, 4-7, 9-12, 14-17, 19 and 20, as well as variants and fragments thereof.

    Delta-endotoxin genes and methods for their use
    8.
    发明授权
    Delta-endotoxin genes and methods for their use 有权
    δ-内毒素及其使用的基因和方法

    公开(公告)号：EP1947184B1

    公开(公告)日：2011-03-30

    申请号：EP08005377.0

    申请日：2004-02-20

    申请人： Athenix Corporation

    发明人： Carozzi, Nadine ,  Hargiss, Tracy ,  Koziel, Michael G. ,  Duck, Nicholas B. ,  Carr, Brian

    IPC分类号： C12N15/32 ,  C12N15/82 ,  C12N5/14 ,  C12N15/63 ,  A01H1/00 ,  C07K14/325 ,  C07K16/12 ,  A01N63/00

    CPC分类号： C12N15/8286 ,  C07K14/325 ,  Y02A40/162

    摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin and delta-endotoxin-associated polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin and delta-endotoxin-associated nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequences shown in SEQ ID NOS: 3, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, and 29, and the nucleotide sequences set forth in SEQ ID NOS: 1, 2, 4, 6, 8, 10, 12, 13, 15, 17, 19, 21, 23, 25, 26, and 28, as well as variants and fragments thereof.