IMPROVED DEVICE FOR STERILISING FLEXIBLE BAGS BY ELECTRON-BEAM IRRADIATION AND METHOD FOR STERILISING THEM

    公开(公告)号:EP4290983A3

    公开(公告)日:2024-02-28

    申请号:EP23206139.0

    申请日:2020-03-26

    摘要: Improved device for sterilising flexible bags by electron-beam irradiation and method for sterilising them
    This invention relates to the pharmaceutical sector, specifically to an improved device for electron-beam irradiation sterilisation of flexible bags, in particular the type of flexible bags that may contain human plasma protein solutions for therapeutic use. This device comprises two electron accelerators: a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. In addition, the present invention relates to a sterilisation method by electron-beam irradiation of such flexible bags and to an in-line filling process for flexible bags using the sterilisation device and method of this invention.

    CYCLOTRON CAPABLE OF ACCELERATING ALPHA PARTICLES AND H2+ PARTICLES, AND HIGH-GAIN METHOD AND HIGH-PRECISION METHOD

    公开(公告)号:EP4319493A1

    公开(公告)日:2024-02-07

    申请号:EP22936716.4

    申请日:2022-09-15

    摘要: The present application provides a cyclotron and a high-gain, high-precision method for accelerating α particles and H 2 + particles. The cyclotron comprises a dual ECR ion source system, a dual-beam injection and transmission system based on magnetic analyzer, a main magnet system, a high-frequency system based on 8th harmonics, and a dual-beam extraction system for precise control of α beam energy using deflector. The high-gain method includes doubling the frequency of the RF cavity, reducing the cavity height and the angle of the dees by half compared to the 4th harmonic high-frequency cavity, and adapting the internal rod diameter, cavity outer radius, angle width, and dees thickness accordingly. The high-precision method includes setting the beam extraction point position, observing the radial distribution of the beam on the target, and adjusting the deflector position in real-time during beam commissioning. In the present application, a cyclotron capable of accelerating alpha and H 2 + particles is developed for the first time in the world; a double-beam high-brightness merging injection of the particles and the H 2 + particles is realized for the first time, and a compact cyclotron uses an eighth-harmonic high-frequency cavity for acceleration for the first time.

    SUPERCONDUCTING UNDULATOR DEVICE
    5.
    发明公开

    公开(公告)号:EP4297538A1

    公开(公告)日:2023-12-27

    申请号:EP22305915.5

    申请日:2022-06-24

    IPC分类号: H05H7/04

    摘要: The present disclosure relates to an undulator device (300) comprising:
    - at least a first superconducting coil structure (302); and
    - at least a second superconducting coil structure (304) positioned opposite the first superconducting coil structure; wherein the first and second superconducting coil structures are separated by a gap (h g ) dedicated to the passage of an electron beam having an electron beam trajectory (314) around a beam axis (310), the beam axis being in a first direction (X) ;
    wherein each superconducting coil structure includes at least a groove (332, 334) through the thickness (h m ) of said superconducting coil structure to separate it into a plurality of elementary coils; the at least one groove being configured in such a way that a current flowing in the superconducting coil structure between the at least one groove can flow alternately in two different orientations, for example into substantially two opposite orientations, in said superconducting coil structure.

    CONFIGURABLE LINEAR ACCELERATOR SYSTEMS AND METHODS

    公开(公告)号:EP4224999A3

    公开(公告)日:2023-08-16

    申请号:EP23166090.3

    申请日:2019-05-17

    IPC分类号: H05H7/02

    摘要: A system comprises a first control logic (112, 302, 304, 306, 812) configured to receive a first trigger and generate a second trigger in response to the first trigger, the second trigger having a second trigger configurable delay relative to the first trigger; a second control logic (112, 302, 304, 306, 812) configured to receive the second trigger and generate a third trigger in response to the second trigger, the third trigger having a third trigger configurable delay relative to the second trigger; a third control logic (112, 302, 304, 306, 812) configured to receive the second trigger and generate a fourth trigger in response to the second trigger, the fourth trigger having a fourth trigger configurable delay relative to the second trigger; a particle power source (106) including the second control logic (112, 302, 304, 306, 812) and configured to generate a particle power signal (118) in response to the third trigger; and a radio frequency, RF, power source (108, 808) including the third control logic (112, 302, 304, 306, 812) and configured to generate an RF power signal (120) in response to the fourth trigger.

    CIRCULAR ACCELERATOR AND PARTICLE THERAPY SYSTEM

    公开(公告)号:EP4195883A2

    公开(公告)日:2023-06-14

    申请号:EP22209625.7

    申请日:2022-11-25

    申请人: Hitachi, Ltd.

    摘要: There is provided a circular accelerator that accelerates a beam of charged particles circulating in a magnetic field such that a closed orbit for each energy of the beam is eccentric. The circular accelerator includes a beam extraction port for extracting beams of different energies from the closed orbit, a first bending magnet and a second bending magnet that bend the beam extracted from the beam extraction port, and a control unit that controls magnetic field strengths of the first bending magnet and the second bending magnet in accordance with the energy of the extracted beam. When the energy of the extracted beam is a designed maximum energy of the circular accelerator, the control unit excites both the first bending magnet and the second bending magnet to bend the beam.