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公开(公告)号:EP4462377A1
公开(公告)日:2024-11-13
申请号:EP24171995.4
申请日:2024-04-23
发明人: Buschle, Lukas , Steinke, Bernd , Haag, Simon , Jasmin, Keuser
摘要: Die Erfindung betrifft ein Verfahren zur zumindest teilweisen optischen Überlagerung von mindestens einer Information im Vordergrund eines mit einer medizinischen Bildgebungsvorrichtung aufgenommenen digitalen Bildes von einem Betrachtungsbereich mit Bildinformationen, die dem, im Blickfeld der medizinischen Bildgebungsvorrichtung, durch die wenigstens eine Information verdecktem Bereich entspricht.
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公开(公告)号:EP4462231A1
公开(公告)日:2024-11-13
申请号:EP22920424.3
申请日:2022-10-28
申请人: NTT DOCOMO, INC.
发明人: ISHIKAWA, Hironori
摘要: Provided is a human augmentation platform device 100, including: a physical information acquisition unit 110 that acquires physical information indicating a physical ability on a sensing side and a physical ability on a controlled side; a motion data acquisition unit 120 that acquires motion data on the sensing side; a control data generation unit 150 that generates control data on the controlled side on the basis of the physical information acquired by the physical information acquisition unit 110 and the motion data acquired by the motion data acquisition unit 120; and an actuation unit 160 that actuates a body on the controlled side on the basis of the control data. The control data generation unit 150 generates the control data within a range of the physical ability on the controlled side.
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公开(公告)号:EP4461858A1
公开(公告)日:2024-11-13
申请号:EP24174908.4
申请日:2024-05-08
发明人: LINDNER, Torsten , ERDEM, Gueltekin , SAEVECKE, Dirk , DESAI, Prashant , DAHRINGER, Jörg Thomas , KLINT, Søren Tang , GUTMANN, Patrick , BERGMANN, Mads Rudbeck
IPC分类号: D04H1/425 , D01D5/08 , D01F1/10 , D01F6/46 , D04H1/544 , D04H1/74 , D04H1/541 , A61F13/511 , A61F13/514 , A61L15/34 , A61K8/02 , D01D5/098
摘要: A carded calendered nonwoven comprising synthetic staple fibers, wherein the synthetic staple fibers comprise a polypropylene polymer matrix, an ethylenepropylene copolymer and a fatty acid amide. The nonwovens may be used in application where a soft and affordable nonwoven is desired, for example disposable absorbent articles such as diapers.
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公开(公告)号:EP4461765A1
公开(公告)日:2024-11-13
申请号:EP23803051.4
申请日:2023-05-12
申请人: Yan, Yunsong
发明人: Yan, Yunsong
IPC分类号: C08J3/075 , C08L101/14 , A61L27/52
摘要: Provided in the present invention is a hydrogel. The hydrogel comprises water, glycerol, cellulose ether, and a polymer. The polymer comprises a first polymer and a second polymer. The first polymer is polyacrylonitrile. The second polymer is a cross-linked polyacrylic acid or a cross-linked poly N-hydroxyethyl acrylamide. Further provided are a premix for preparing the hydrogel and a method for preparing the hydrogel. Further provided is a pharmaceutical composition. The pharmaceutical composition can be at least one of a transdermal patch, a wound care patch, a skin care patch and a tissue regeneration patch, and is applied to the fields of medical biology, medical beauty, skin care, etc. Further provided is the application of the hydrogel in preparation of a sensor, an actuator, a transistor, a capacitor, a garment material and a battery. The present hydrogel has better bonding performance, mechanical performance, durability, transparency and air permeability, and also has good drug loading performance and drug sustained-release performance.
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5.
公开(公告)号:EP4461735A1
公开(公告)日:2024-11-13
申请号:EP23737031.7
申请日:2023-01-04
发明人: ZHANG, Chen , LIAO, Yuting , ZHAO, Chenfei , YU, Yan , TANG, Pingming , MA, Junjie , CHEN, Xiaogang , YUAN, Shuai , CHENG, Xinfan , YE, Fei , LI, Yao , NI, Jia , YAN, Pangke
IPC分类号: C07D519/00 , C07D487/04 , A61K31/519 , A61K47/55 , A61P29/00 , A61P35/00 , A61P37/00
摘要: The present invention relates to a compound represented by general formula (I) or a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or eutectic crystal thereof, and an intermediate thereof, and use thereof in IRAK4-related diseases such as an autoimmune disease, an inflammatory disease or cancer. B-L-K (I)
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公开(公告)号:EP4461731A1
公开(公告)日:2024-11-13
申请号:EP23172992.2
申请日:2023-05-12
申请人: Universität Zürich
发明人: ZALESAK, Frantisek , NAI, Francesco , BEDI, Rajiv , HEROK, Marcin , ERRANI, Francesco , IVERNIZZI, Annalisa , LI, Yaozong , CAFLISCH, Amedeo
IPC分类号: C07D473/34 , C07D473/40 , C07D487/04 , A61K31/52 , A61P35/00
摘要: The present invention relates to a compound of formula (I) or (II)
for use as a medicament in the treatment of cancer.-
公开(公告)号:EP4461726A1
公开(公告)日:2024-11-13
申请号:EP23737354.3
申请日:2023-01-03
IPC分类号: C07D209/44 , A61K31/4035 , A61K31/4439 , A61K31/4155 , A61K31/506 , A61P19/02 , C07D403/04 , C07D401/04 , C07D487/04 , C07D405/04
摘要: The present invention provides a novel isoindolinone derivative compound, a hydrate thereof, a solvate thereof or a pharmaceutically acceptable salt thereof, as caspase inhibitors. The novel isoindolinone derivative compound of the present invention was confirmed to exhibit an excellent interleukin-1β(IL-1β) reducing effect and an excellent apoptosis-reducing effect, thus exhibiting excellent activity as a caspase inhibitor, and thus, it has been found that the novel isoindolinone derivative compound can be used for the prevention or treatment of caspase-related diseases.
Therefore, the novel isoindolinone derivative compound of the present invention can be effectively used in the prevention or treatment of caspase-related diseases in the medical and pharmaceutical fields.-
公开(公告)号:EP4461402A1
公开(公告)日:2024-11-13
申请号:EP24167389.6
申请日:2024-03-28
发明人: OJIRI, Michelle , BURRESS, Jacob
IPC分类号: B01J20/04 , A61L9/014 , B01D39/00 , B01J20/06 , B01J20/20 , B01J20/22 , B01J20/28 , B01J20/32 , A62B23/02
摘要: A sorbent filter (5, 105, 205, 305) and air filter assembly (1) includes at least a first adsorbent layer (10, 110, 210, 310) and a second adsorbent layer (20, 120, 220, 320). The first adsorbent layer (10, 110, 210, 310) can include one of a metal organic framework (MOF) or activated carbon. The second adsorbent layer (20, 120, 220, 320) is positioned adjacent the first adsorbent layer (10, 110, 210, 310) and can include an adsorbent material with water.
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9.
公开(公告)号:EP4461373A2
公开(公告)日:2024-11-13
申请号:EP24202055.0
申请日:2012-09-12
发明人: SWERGOLD, Gary
IPC分类号: A61P43/00
摘要: The present invention provides methods for reducing lipoprotein(a) (Lp(a)) in patients. The methods of the present invention comprise selecting a patient who exhibits elevated serum Lp(a), and administering to the patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P.
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10.
公开(公告)号:EP4461370A2
公开(公告)日:2024-11-13
申请号:EP24191518.0
申请日:2020-01-08
申请人: Celgene Corporation
发明人: WONG, Lilly L.
IPC分类号: A61P35/00
摘要: Provided herein are methods of using 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, in combination with a second active agent for treating, preventing or managing multiple myeloma. The second active agent is one or more of a BTK inhibitor, an mTOR inhibitor, a PIM inhibitor, an IGF-1R inhibitor, an MEK inhibitor, an XPO1 inhibitor, a DOT1L inhibitor, an EZH2 inhibitor, a JAK2 inhibitor, a BRD4 inhibitor, a PLK1 inhibitor, an NEK2 inhibitor, an AURKB inhibitor, a BIRCS inhibitor, a BET inhibitor, or a DNA methyltransferase inhibitor.
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