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公开(公告)号:EP4380606A1
公开(公告)日:2024-06-12
申请号:EP22851488.1
申请日:2022-08-04
发明人: TORRESI, Joseph
IPC分类号: A61K39/00 , A61K39/12 , A61K39/145 , A61K39/215 , A61K39/29 , A61P31/12 , C12N7/00 , C07K14/005 , C07K14/18
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公开(公告)号:EP4368633A1
公开(公告)日:2024-05-15
申请号:EP22837882.4
申请日:2022-06-29
发明人: RHEE, Joon Haeng , LEE, Shee Eun , PUTH, Sao , KHIM, Koemchhoy
IPC分类号: C07K14/28 , A61K39/39 , A61P31/16 , A61K39/145 , A61K39/00
摘要: The present invention relates to: deimmunized flagellin that does not induce the production of flagellin-specific antibodies; and use thereof. In particular, the present invention relates to a flagellin variant in which a major epitope that forms an antibody against flagellin is deleted, the flagellin variant being characterized by, when used as a vaccine adjuvant, not producing antibodies against flagellin while maintaining an excellent immune enhancer effect.
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3.
公开(公告)号:EP3715459B1
公开(公告)日:2024-04-24
申请号:EP18881872.8
申请日:2018-06-01
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公开(公告)号:EP4326318A1
公开(公告)日:2024-02-28
申请号:EP21940213.8
申请日:2021-05-21
发明人: WANG, Huiru
IPC分类号: A61K39/215 , A61K39/145 , A61P31/14 , A61P31/16 , G01N33/569
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公开(公告)号:EP4323382A1
公开(公告)日:2024-02-21
申请号:EP22787753.7
申请日:2022-04-15
发明人: RYU, Jin-Hyeob , LEE, Sang Moo , KIM, Eun Ha , SEONG, Rak Kyun , MIN, Hyun Su , LIM, Yu Na
IPC分类号: C07K14/005 , C07K14/47 , A61K39/215 , A61K39/145 , A61K9/107 , A61K47/10 , A61K47/18 , A61K47/22
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公开(公告)号:EP3774884B1
公开(公告)日:2023-12-06
申请号:EP19719672.8
申请日:2019-03-27
IPC分类号: C07K16/10 , A61K39/145 , C07K14/005
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公开(公告)号:EP4274607A1
公开(公告)日:2023-11-15
申请号:EP22701813.2
申请日:2022-01-10
申请人: ModernaTX, Inc.
IPC分类号: A61K39/12 , A61K39/145 , A61P31/14
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8.
公开(公告)号:EP4251200A1
公开(公告)日:2023-10-04
申请号:EP21815535.6
申请日:2021-11-30
发明人: WOLSCHEK, Markus , FERKO, Boris
IPC分类号: A61K39/145 , C07K14/11
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公开(公告)号:EP3251680B1
公开(公告)日:2023-09-20
申请号:EP17163093.2
申请日:2009-05-22
发明人: REED, Steven G. , CARTER, Darrick
IPC分类号: A61K31/7028 , A61K39/008 , A61K39/04 , A61K39/145 , A61P37/00
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公开(公告)号:EP4240329A1
公开(公告)日:2023-09-13
申请号:EP21889949.0
申请日:2021-11-03
发明人: VARADARAJAN, Navin , LIU, Xinli
IPC分类号: A61K9/127 , A61K47/69 , A61K39/145 , A61K39/00 , A61K39/215 , A61P31/14 , A61P31/16 , A61P35/00
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