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    STABILIZED ALL-AQUEOUS EMULSIONS AND METHODS OF MAKING AND USING THEREOF
    8.
    发明公开
    STABILIZED ALL-AQUEOUS EMULSIONS AND METHODS OF MAKING AND USING THEREOF 审中-公开
    STABILISIERTEWÄSSRIGEEMULSIONEN UND VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DAVON

    公开(公告)号：EP3079804A4

    公开(公告)日：2017-08-30

    申请号：EP14869152

    申请日：2014-12-09

    申请人： VERSITECH LTD

    发明人： SONG YANG ,  LIU ZHOU ,  SHUM HO CHEUNG

    IPC分类号： B01J13/10 ,  B01D11/04 ,  B01F5/00

    CPC分类号： A61K9/107 ,  A61K9/0019 ,  A61K9/0095 ,  A61K47/10 ,  A61K47/36 ,  B01F3/0803 ,  B01F3/0815 ,  B01F5/0085 ,  B01F17/0092

    摘要： Methods for preparing all-aqueous emulsions, including stable emulsions or emulsions having high viscosity and/or ultra-low interfacial tension are described. The method includes mixing, combining, or contacting a first electrically charged phase containing a first solute (e.g., dispersed phase) with at least a second phase containing a second solute (e.g., continuous phase). The solutes are incompatible with each other. The electrostatic forces between the two phases induce the formation of droplets of a dispersed phase in a continuous phase. The dispersed and continuous phases contain oppositely charged molecules, such as surfactants or other macromolecules and colloids which stabilize the drops of the dispersed phase. Complex coacervation of the oppositely charged molecules or colloids at the interface of the two aqueous phases results in formation of a membrane or barrier which prevents coalescence or aggregation of the droplets. The membrane also prevents leakage of any encapsulated agents from the droplets.

    摘要翻译： 描述了制备全水乳液的方法，包括具有高粘度和/或超低界面张力的稳定乳液或乳液。 该方法包括将含有第一溶质（例如分散相）的第一带电相与含有第二溶质（例如连续相）的至少第二相混合，组合或接触。 溶质彼此不相容。 两相之间的静电力导致在连续相中形成分散相的液滴。 分散相和连续相包含带相反电荷的分子，例如表面活性剂或其他稳定分散相液滴的大分子和胶体。 在两个水相的界面处带相反电荷的分子或胶体的复合凝聚导致形成阻止液滴聚结或聚集的膜或屏障。 该膜还防止任何包封剂从液滴泄漏。