公开(公告)号：EP4461738A1

公开(公告)日：2024-11-13

申请号：EP23172136.6

申请日：2023-05-08

申请人： Julius-Maximilians-Universität Würzburg

发明人： MEINEL, Lorenz ,  GUTMANN, Marcus Otto ,  REINHARDT, Debora ,  TER MORS, Bjoern ,  DRIEßEN, Marc

IPC分类号： C07K7/06 ,  G01N33/58

摘要： The present invention relates to diagnostic furin sensors, respective furin sensitive peptides and related kits. The invention further relates to methods and medical uses involving said sensors, peptides or kits, such as methods for diagnosing cancer (particularly HNSCC), in a subject, as well as to methods for determining furin activity.

公开(公告)号：EP4453236A1

公开(公告)日：2024-10-30

申请号：EP22854698.2

申请日：2022-12-21

申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： RONZETTI, Michael H. ,  HENDERSON, Mark J. ,  SANCHEZ, Tino W. ,  MICHAEL, Samuel G. ,  VOSS, Ty C. ,  BALJINNYAM, Bolormaa ,  SIMEONOV, Anton

IPC分类号： C12Q1/66 ,  G01N33/58 ,  G01N33/68 ,  G01N33/542

公开(公告)号：EP4449130A2

公开(公告)日：2024-10-23

申请号：EP22908531.1

申请日：2022-12-19

申请人： bioAffinity Technologies, Inc.

发明人： REBEL, Vivienne, I. ,  LEMIEUX, Madeleine, E.

IPC分类号： G01N33/68 ,  G01N33/58 ,  G01N33/574

公开(公告)号：EP4446744A2

公开(公告)日：2024-10-16

申请号：EP24183773.1

申请日：2019-07-12

申请人： Goryo Chemical, Inc. ,  Hamamatsu Photonics K.K.

发明人： MINOURA, Itsushi ,  TEZUKA, Yoshiaki ,  HIRAWAKE, Kazumasa

IPC分类号： G01N33/58

摘要： The purpose of the present invention is to provide a method for allowing a target cell to emit light, in which the target cell is present inside of a cell mass and is aimed to emit light by a fluorescent probe. The present invention provides a method for allowing the target cell to emit fluorescence comprising removing calcium ions from within the cell mass or a tissue containing the target cell and contacting the cell mass or the tissue with the fluorescent probe which emits fluorescence when contacted with or taken up into the target cell, thereby allowing the target cell present inside of the cell mass or the tissue to emit light, and thus can be used in a detection of the target cell in a sample, such as a clinical sample, in which the target cell may not be present on the surface of the sample.

公开(公告)号：EP3254113B1

公开(公告)日：2024-10-09

申请号：EP16747366.9

申请日：2016-02-05

IPC分类号： G01N33/58 ,  G01N33/566

CPC分类号： G01N33/56916 ,  C12Y113/12007

公开(公告)号：EP4437347A1

公开(公告)日：2024-10-02

申请号：EP22822461.4

申请日：2022-11-25

申请人： Centre Hospitalier Universitaire de Bordeaux ,  ASSISTANCE PUBLIQUE HOPITAUX DE PARIS ,  Institut National de la Santé et de la Recherche Médicale (INSERM) ,  SORBONNE UNIVERSITE

发明人： GALICHON, Pierre ,  BOFFA, Jean-Jacques ,  BUOB, David ,  ORIEUX, Arthur ,  VERNEY, Charles

IPC分类号： G01N33/68 ,  G01N33/58

CPC分类号： G01N33/6893 ,  G01N2800/34720130101 ,  G01N2800/6020130101 ,  G01N2333/7620130101

公开(公告)号：EP4300100A3

公开(公告)日：2024-09-04

申请号：EP23208723.9

申请日：2011-10-13

申请人： Meso Scale Technologies, LLC

发明人： KUMAR, Sudeep ,  SIGAL, George ,  TSIONSKY, Michael

IPC分类号： G01N33/53 ,  G01N33/58 ,  G01N33/52 ,  G01N33/543

CPC分类号： G01N33/54386

摘要： The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.

公开(公告)号：EP3962510B1

公开(公告)日：2024-08-28

申请号：EP20720320.9

申请日：2020-04-30

IPC分类号： A61K38/00 ,  A61K48/00 ,  C07K7/08 ,  C12N15/86 ,  A61K47/62 ,  A61K47/64 ,  G01N33/58

CPC分类号： G01N33/582 ,  C07K7/08 ,  C07K2319/3320130101 ,  A61K38/00 ,  G01N2333/72620130101 ,  G01N2800/5220130101 ,  G01N2500/0020130101 ,  G01N2500/0220130101

公开(公告)号：EP4057002B1

公开(公告)日：2024-08-07

申请号：EP20887834.8

申请日：2020-11-12

IPC分类号： C09K11/06 ,  G01N15/1433 ,  G01N33/58 ,  G01N21/19

CPC分类号： C09K11/06 ,  G01N21/19 ,  G01N2021/643920130101 ,  C09K2211/100720130101 ,  C09K2211/10420130101 ,  C09K2211/105520130101 ,  G01N33/582 ,  G01N15/1433

公开(公告)号：EP3822359B1

公开(公告)日：2024-08-07

申请号：EP19833189.4

申请日：2019-07-12

IPC分类号： C12Q1/04 ,  G01N21/64 ,  G01N33/48 ,  G01N33/53 ,  G01N33/574 ,  G01N33/58

CPC分类号： G01N33/574 ,  G01N33/582 ,  G01N21/6428 ,  G01N33/5306