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公开(公告)号：JPH0458947B2
公开(公告)日：1992-09-18
申请号：JP15101988
申请日：1988-06-17
申请人： KANEBO LTD
发明人： UCHIWA HIDEYO , SUGAI RYUJI , MURAKAMI UMEJI , TAKEMOTO TAIRA
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公开(公告)号：JPH0372849A
公开(公告)日：1991-03-28
申请号：JP20892089
申请日：1989-08-11
申请人： KANEBO LTD
发明人： KIZAWA KENJI , NAGANUMA KEIKO , MURAKAMI UMEJI , TAKEMOTO TAIRA , MAEDA MASAO , UCHIUMI KENJI , IGUCHI KEIJI
摘要： PURPOSE:To obtain a health food effective in relaxing excessive psychosomatic stress and keeping the mind and body in calm state by using a peptide mixture (salt) having a molecular weight distribution falling within a specific range and obtained by the fractionation of a hydrolyzate produced by hydrolyzing milk casein with a pepsin. CONSTITUTION:The objective food contains a peptide mixture (salt) having a molecular weight distribution falling between 200 and 52,000 and obtained by the fractionation of a hydrolyzate produced by hydrolyzing milk casein with a pepsin.
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公开(公告)号：JPH0220263A
公开(公告)日：1990-01-23
申请号：JP16968588
申请日：1988-07-07
申请人： KANEBO LTD
发明人： SUGAI RYUJI , MURAKAMI UMEJI , TAKEMOTO TAIRA
摘要： PURPOSE:To provide the title composition excellent in safety and vasodepressor activity, made up of, as an active ingredient, a peptide (or its acid-added salt) represented by Thr-Thr-Met-Pro-Leu-Trp. CONSTITUTION:The objective composition for oral intake (e.g. food, drug) for vasodepressor use, made up of, as an active ingredient, a peptide or its acid- added salt (e.g. hydrochloride) represented by Thr-Thr-Met-Pro-Leu-Trp. The above-mentioned peptide, being well-established, can be prepared, for example, by the following process: casein of bovine origin is degraded at a pH 5 - 9 by trypsin, and from the resulting degraded product undegraded casein is precipitated and removed by heating or acid treatment followed by concentration of the mother liquor and then purification; alternatively, it can be prepared by use of an organic chemical synthetic technique.
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公开(公告)号：JPS63141996A
公开(公告)日：1988-06-14
申请号：JP28828686
申请日：1986-12-03
发明人： MARUYAMA SUSUMU , TANAKA HIDEOKI , TOMIZUKA NOBORU , SUZUKI HIDEO , SUGAI RYUJI , MORITA KAZUYOSHI , TAKEMOTO TAIRA
摘要： NEW MATERIAL:L-prolyl-L-tyrosyl-L-proline and its acid addition salt. USE:A hypotensor. It has angiotensinase inhibiting activity and low toxicity and is expected to be useful as a medicine or health food, etc., for depressing the blood pressure level. PREPARATION:Amino acid are introduced into a desired sequence e.g. by a peptide synthesis comprising a proper combination of the protection, condensation and deprotection of NH2 group or COOH group of amino acid.
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公开(公告)号：JPS6352872A
公开(公告)日：1988-03-07
申请号：JP19769286
申请日：1986-08-22
发明人： KASHIKI HIROAKI , NAITO KAZUMI , TAKEMOTO TAIRA
摘要： PURPOSE:To carry out differentiation and multiplication of plant organ efficiently and to suppress occurrence of browning and dedifferentiation, etc., of the organ, by adding brassinolide to a culture medium of plant organ. CONSTITUTION:In differentiating and multiplying a plant organ (adventitious bud or advertitious root, etc.) from a differentiated tissue such as plant piece, etc., or a dedifferentiated tissue(callus) by culture in a solid medium or a liquid medium, brassinolide is added to the medium. The addition concentration is preferably 1X10 -1X10 ppm, especially 1X10 -1X10 ppm. A plant hormone together with the brassinolide is preferably added to the medium. The effects are excellent when the plant organ is adventitious bud.
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公开(公告)号：JPS6178380A
公开(公告)日：1986-04-21
申请号：JP20285484
申请日：1984-09-26
申请人： Kanebo Ltd
发明人： KASHIKI HIROAKI , IDA ETSUKO , TAKEMOTO TAIRA , NAKAO KAZUO , INUI MASAYOSHI
摘要： PURPOSE: To enable the easy separation of a cultured plant tissue without damaging the cultured product, by culturing a plant tissue in a gel medium convertible reversibly between gel and sol, and converting the medium to a sol after cultivation.
CONSTITUTION: A substance convertible between sol and gel with temperature (e.g. gelatin) or a substance which forms a gel in the state dispersed in water but becomes sol by shaking (e.g. aluminum hydroxide, iron hydroxide, vanadium pentoxide, etc.) is added to a culture medium. A plant tissue is cultured in the medium, and after the cultivation, the medium is converted to sol, and the cultured product is separated from the medium e.g. by filtration.
COPYRIGHT: (C)1986,JPO&Japio摘要翻译： 目的：为了使培养的植物组织容易分离而不破坏培养产物，通过在凝胶和溶胶之间可逆地转化的凝胶介质中培养植物组织，并在培养后将培养基转化为溶胶。 构成：在溶胶和凝胶之间可转换温度的物质（例如明胶）或形成分散在水中的状态的凝胶的物质通过摇动变成溶胶（例如氢氧化铝，氢氧化铁，五氧化二钒等）加入到 培养基。 在培养基中培养植物组织，培养后将培养基转化成溶胶，将培养的产物从培养基中分离， 通过过滤。
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公开(公告)号：JPS6157228A
公开(公告)日：1986-03-24
申请号：JP18017784
申请日：1984-08-28
申请人： Kanebo Ltd
发明人： MORITA KAZUYOSHI , TAKEMOTO TAIRA , MATSUI TADASHI , MORI KENJI , NAGASAWA HISANAO , OTANI YASUNAGA , ARAI SOICHI
IPC分类号： A23L29/10 , A61K8/00 , A61K8/06 , A61K8/30 , A61K8/44 , A61K8/64 , A61K8/65 , A61Q1/02 , A61Q19/00 , A61Q19/10 , B01F17/00 , B01F17/30 , C12P21/00
CPC分类号： A61K8/44 , A61K8/06 , A61K8/64 , A61K8/645 , A61K8/65 , A61Q1/02 , A61Q19/00 , A61Q19/10 , B01F17/005
摘要： PURPOSE:To perform desalting and concn. within a short time, by bonding the amino group part of amino acid ester represented by a specific general formula to the carboxyl terminal of a hydrophilic protein hydrolysate through an amino linkage before dialyzing the reaction product. CONSTITUTION:The amino group part of amino acid ester represented by formula R1OR2 (wherein R1 is an amino acid residue and R2 is a saturated or unsaturated hydrocarbon group) is bonded to the carboxyl terminal of a hydrophilic protein hydrolysate through an amido linkage and the obtained reaction product is dialyzed to obtain a proteinaceous emulsifier. As the aforementioned hydrophilic protein hydrolysate, there are casein, gelatin, sericine, soluble collagen, zein or serum albumin. As the aforementioned dialytic method, a method using a hollow fiber type ultrafiltration membrane can be employed.
摘要翻译： 目的：进行脱盐和浓缩 在短时间内，通过在透析反应产物之前通过氨基键将由特定通式表示的氨基酸酯的氨基部分键合到亲水性蛋白质水解产物的羧基末端。 构成：式R1OR2（式中，R1为氨基酸残基，R2为饱和或不饱和烃基）表示的氨基酸的氨基部分通过酰胺键与亲水性蛋白质水解物的羧基末端键合，得到 透析反应产物，得到蛋白质乳化剂。 作为上述亲水性蛋白质水解物，存在酪蛋白，明胶，丝氨酸，可溶性胶原，玉米醇溶蛋白或血清白蛋白。 作为上述透析法，可以使用使用中空纤维型超滤膜的方法。
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公开(公告)号：JPS60252407A
公开(公告)日：1985-12-13
申请号：JP10889684
申请日：1984-05-28
申请人： KANEBO LTD
发明人： TAKEMOTO TAIRA , MORI KENJI
IPC分类号： A61K8/72 , A61K8/06 , A61K8/31 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/88 , A61K8/89 , A61K8/891 , A61K8/92 , A61K8/97 , A61K8/98
摘要： PURPOSE:To obtain the titled cosmetic having excellent emulsion stability, viscosity stability, moisture-retainability, feeling, durability on the skin, etc., free from irritation to the skin, and useful for the treatment of skin, hair, etc., by mixing a specific water-soluble polyamide with a specific oleagenous substance for cosmetic, and water. CONSTITUTION:An emulsion-type cosmetic can be prepared by (1) adding a water-soluble polyamide having a relative viscosity of 1.9-2.5, containing the recurring unit of formula I and obtained by the homopolymerization of alpha-(N,N-dimethylamino)-epsilon-caprolactam, or a water-soluble polyamide having a relative viscosity of 1.9-2.5 and containing >=40mol% structural unit of formula II obtained by the copolymerization of the above epsilon-caprolactam derivative and epsilon- caprolactam and
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