公开(公告)号：JPH05201922A

公开(公告)日：1993-08-10

申请号：JP16461792

申请日：1992-06-23

Applicant: BASF AG

Inventor： FURANTSU MERUGAA ,  TOMU BUITSUTSUERU ,  MARUTEIN BURUUDAAMIYURAA

IPC: B01J21/02 ,  B01J21/06 ,  B01J29/06 ,  C07B61/00 ,  C07C67/297 ,  C07C69/007 ,  C07C69/16 ,  C07C69/28

公开(公告)号：JPH05503077A

公开(公告)日：1993-05-27

申请号：JP51552290

申请日：1990-10-02

IPC: A61K31/12 ,  A61K31/215 ,  A61K31/22 ,  A61K31/27 ,  A61P35/00 ,  C07C45/45 ,  C07C45/46 ,  C07C45/65 ,  C07C45/67 ,  C07C49/665 ,  C07C49/67 ,  C07C49/683 ,  C07C49/727 ,  C07C49/737 ,  C07C49/747 ,  C07C49/753 ,  C07C49/755 ,  C07C69/007 ,  C07C69/757 ,  C07C271/12

公开(公告)号：JPH0543510A

公开(公告)日：1993-02-23

申请号：JP20194691

申请日：1991-08-12

Applicant: WAKAYAMA PREFECTURE ,  MIKI RIKEN KOGYO KK

Inventor： TANIGUCHI HISAJI ,  NOMURA EISAKU ,  NAKAGAWA KAZUSHIRO ,  KAWAGUCHI KOICHI

IPC: B01J31/02 ,  C07B61/00 ,  C07C67/10 ,  C07C69/007 ,  C07C69/78 ,  C07C205/42

Abstract: PURPOSE:To easily obtain the required ester in high yield by using a calix- allene-polyethylene glycol condensate as a catalyst. CONSTITUTION:The objective ester of formula R3-O-CO-R4 is produced by reacting a compound of formula R3X(R3 is alkyl; X is halogen) with a compound of formula R4COOM (R4 is alkyl; M is Na, K or Li) in a solvent (e.g. methylene chloride, chloride, chloroform, acetonitrile, dioxane or N,N-dimethylformamide) in the presence of a compound of formula (R1 and R2 are alkyl or H; n is 4-8; m is 0-20) as a catalyst preferably at the boiling temperature of the solvent. The catalyst is easily recovered and reused by making adsorbed on alumina, silica gel, activated carbon or active clay after the reaction and desorbed with methanol or ethanol.

公开(公告)号：JPH05500368A

公开(公告)日：1993-01-28

申请号：JP51341890

申请日：1990-09-04

IPC: C07C67/08 ,  C07C69/007 ,  C07C69/54 ,  C07C219/08 ,  C07C229/04 ,  G02F1/361

公开(公告)号：JPH051265B2

公开(公告)日：1993-01-07

申请号：JP14433283

申请日：1983-08-06

Applicant: ZAMBON SPA

Inventor： KURAUDEIO GIORUDAANO ,  GURACHIANO KASUTARUJI

IPC: C07C69/007 ,  C07C51/00 ,  C07C67/00 ,  C07C69/612 ,  C07C69/62 ,  C07C227/00 ,  C07C229/42 ,  C07C301/00 ,  C07C303/30 ,  C07C309/63 ,  C07D321/06 ,  C07D333/24

公开(公告)号：JPH04257543A

公开(公告)日：1992-09-11

申请号：JP2009591

申请日：1991-02-13

Applicant: FUJI PHOTO FILM CO LTD

Inventor： IWAKURA KEN ,  FUKUSHIGE YUICHI

IPC: C07C67/14 ,  C07C69/007

Abstract: PURPOSE:To provide a method for selectively esterifying alcoholic hydroxyl group of a phenolic derivative having the alcoholic hydroxyl group useful as a synthetic intermediate. CONSTITUTION:The subject method is a method for selectively esterifying a phenolic derivative having alcoholic hydroxyl group characterized as follows. The phenolic derivative having a group possessing the alcoholic hydroxyl group as a substituent group is made to react with an acid halide in an organic solvent using an amide or a urea derivative in combination.

公开(公告)号：JPH04154737A

公开(公告)日：1992-05-27

申请号：JP3135990

申请日：1990-02-08

Applicant: OTSUKA PHARMA CO LTD

Inventor： TANAKA TATSUYOSHI ,  SAKURAI YOJI ,  OKAZAKI KOJI ,  HASEGAWA TAKASHI ,  FUKUYAMA YOSHIYASU

IPC: C07D295/08 ,  A61K31/045 ,  A61K31/055 ,  A61K31/08 ,  A61K31/085 ,  A61K31/10 ,  A61K31/12 ,  A61K31/13 ,  A61K31/16 ,  A61K31/19 ,  A61K31/215 ,  A61K31/35 ,  A61K31/351 ,  A61K31/357 ,  A61K31/36 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4035 ,  A61K31/415 ,  A61K38/16 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07C39/15 ,  C07C39/21 ,  C07C39/23 ,  C07C39/367 ,  C07C43/178 ,  C07C43/205 ,  C07C43/215 ,  C07C43/23 ,  C07C43/253 ,  C07C43/295 ,  C07C45/46 ,  C07C46/02 ,  C07C49/83 ,  C07C49/835 ,  C07C49/84 ,  C07C50/30 ,  C07C69/007 ,  C07C69/017 ,  C07C69/712 ,  C07C215/50 ,  C07C215/66 ,  C07C217/14 ,  C07C217/20 ,  C07C217/56 ,  C07C233/18 ,  C07C233/22 ,  C07C317/22 ,  C07C323/12 ,  C07C323/20 ,  C07D207/16 ,  C07D207/26 ,  C07D209/48 ,  C07D233/60 ,  C07D277/24 ,  C07D277/28 ,  C07D295/092 ,  C07D295/096 ,  C07D309/12 ,  C07D317/48 ,  C07D521/00

Abstract: PURPOSE:To provide a pharmaceutical composition containing a biphenyl derivative or a phenyl derivative as an active component and having an action to promote the survival and growth of cholinergic nerve cell of central nervous system and a protecting action on the damage of the cell. CONSTITUTION:The objective agent contains at least one kind of compound selected from the compounds of formula I (R is H, alkyl, alkenyl, phenyl, etc.; R and R are OH, alkanoyloxy, alkoxy, etc.; R is OH, alkoxy, H, alkyl, etc.; R is H, alkyl, alkoxy, phenyl, etc.; R is H, OH, alkyl, alkenyl, etc.; RC is H or alkyl), formula II (R is OH, alkenyloxy, alkoxy, etc.; R and R are alkenyl; R is H or alkenyl; R is OH, alkenyloxy, etc.; R is R or group of formula III), formula IV (RE, RF and RI are alkyl; RG and RF are alkoxy), etc., as an active component. The compound of formula I wherein R and R are OH and R and R are alkenyl is a new material.

公开(公告)号：JPH03291252A

公开(公告)日：1991-12-20

申请号：JP23684390

申请日：1990-09-05

Applicant: SUMITOMO CHEMICAL CO

Inventor： TODA SHOJI ,  AZUMAI TAKAYUKI ,  KURIMOTO ISAO ,  MINAMII MASAYOSHI ,  SEKINE CHIZU ,  TANI TAKESHI ,  FUJISAWA KOICHI

IPC: G02F1/13 ,  C07C33/18 ,  C07C33/20 ,  C07C41/16 ,  C07C43/164 ,  C07C43/178 ,  C07C43/20 ,  C07C43/205 ,  C07C43/23 ,  C07C45/59 ,  C07C45/67 ,  C07C45/71 ,  C07C65/24 ,  C07C67/08 ,  C07C67/10 ,  C07C67/14 ,  C07C69/007 ,  C07C69/017 ,  C07C69/76 ,  C07C69/773 ,  C07C69/92 ,  C09K19/32

Abstract: NEW MATERIAL:A compound expressed by formula I (R is 3-20C alkyl; R is 1-20C alkyl which may be substituted by halogen or 2-20C alkoxyalkyl which may be substituted by halogen; X is COO or OCO; k, l, m and p are 0 or 1 ; n is 0-6; * is asymmetric carbon, provided that when k is 0, l and m are not simultaneously 1 and when k is 1, m is 1 and when n is 0 and m is 1, X is COO). EXAMPLE:(-)-6-(2-Propoxypropyl)-2-naphthalenecarboxylic acid 1-octyl. USE:The compound expressed by formula I is useful as an ingredient for a liquid crystal material having sufficient spontaneous polarization, being responsible at high speed and exhibiting ferroelectric liquid crystal phase in temperature area near ambient temperature. PREPARATION:For example, an optically active naphthalene carboxylic acid derivative expressed by formula II (R' is OH or halogen) is reacted with alcohols expressed by formula III to provide the compound expressed by formula I (m is 1 and X is OCO).

公开(公告)号：JPH03236347A

公开(公告)日：1991-10-22

申请号：JP3339490

申请日：1990-02-13

Applicant: SUMITOMO CHEMICAL CO

Inventor： AZUMAI TAKAYUKI ,  KURIMOTO ISAO ,  TODA SHOJI ,  MINAMII MASAYOSHI

IPC: C07C67/08 ,  C07C65/01 ,  C07C67/14 ,  C07C69/007 ,  C07C69/157 ,  C07C69/24 ,  C07C69/63 ,  C07C69/708

Abstract: NEW MATERIAL:The optically active aromatic carboxylic acid derivative expressed by formula I [R' is (halogenated) 1-20C alkyl or (halogenated) 2-20C alkoxyalkyl; k is 1 or 2; Z is group of formula II, formula III or -(CH2)P- (P is 1-5; * represents asymmetric carbon atom); provided that when Z is -(CH2)P-, R' is optically active group]. EXAMPLE:(+)-4-(2-Propylcarbonyloxypropyl)benzoic acid. USE:An intermediate for organic electronic material, especially a liquid crystal material. An intermediate for agricultural chemicals and pharmaceuticals. PREPARATION:The objective optically active aromatic carboxylic acid derivative of formula I can te produced e.g. by acylating an optically active hydroxycarboxylic acid of formula IV with an acylation agent of formula V [X is halogen or R'C(=O)O-].

公开(公告)号：JPH0357097B2

公开(公告)日：1991-08-30

申请号：JP1521685

申请日：1985-01-29

IPC: C07C67/293 ,  C07C69/007 ,  C07C69/63