-
81.发明专利
公开(公告)号：JP2008024662A
公开(公告)日：2008-02-07
申请号：JP2006200134
申请日：2006-07-22
Applicant: Hamamatsu Univ School Of Medicine , Nisshin Pharma Inc , Oita Univ , 国立大学法人 大分大学 , 国立大学法人浜松医科大学 , 日清ファルマ株式会社
Inventor： FUJIOKA TOSHIO , MURAKAMI KAZUNARI , NAGAI NORIYUKI , SUZUKI YOSHIO , KIMURA NOBUTAKE , SHINODA YUKIO , HIRAMOTO SHIGERU , FURUTA TAKAHISA , SUGIMOTO MITSUSHIGE , KODAIRA TOMOYO , SHIRAI NAOTO , SENOO KAZUTAKA , NAKAJIMA HIROSHI , MATSUSHITA FUMIAKI , KUMAGAI JUNICHI
Abstract: PROBLEM TO BE SOLVED: To provide a preparation for a helicobacter pylori-eradicating agent effective for patients who could not be eradicated by a conventional therapy of using 3 administering agents as combined, and a method of eradication.
SOLUTION: This helicobacter pylori-eradicating agent effective for patients who could not be eradicated by the conventional therapy of using 3 administering agents consisting of the antibiotics of amoxycillin and clarithromycin, and a proton pump inhibitor as combined, consists of the above three agents and a browning reaction product of a sugar with protein, and the method for eradicating the same by administering the above four agents is also provided.
COPYRIGHT: (C)2008,JPO&INPITAbstract translation: 要解决的问题：提供对通过使用3种给药剂组合的常规疗法不能根除的患者有效的幽门螺杆菌消除剂的制备方法和根除方法。 解决方案：对于通过常规治疗使用由阿莫西林和克拉霉素的抗生素组成的3种给药剂和质子泵抑制剂组合的不能根除的患者，该幽门螺旋杆菌根除剂由上述三种 还提供了糖与蛋白质的药剂和褐变反应产物，并且还提供了通过施用上述四种药剂来消除其的方法。 版权所有（C）2008，JPO＆INPIT
-
公开(公告)号：JP4009251B2
公开(公告)日：2007-11-14
申请号：JP2003538161
申请日：2002-10-08
Applicant: 日清ファルマ株式会社 , 杏林製薬株式会社
IPC: C07D405/12 , A61K31/4525 , A61K31/4545 , A61K31/497 , A61K31/5377 , A61P1/00 , A61P1/04 , A61P1/08 , A61P1/10 , A61P17/04 , A61P25/04 , A61P43/00 , C07D211/58 , C07D401/12 , C07D405/14 , C07D413/14
CPC classification number: C07D401/12 , C07D211/58 , C07D405/12 , C07D405/14 , C07D413/14
-
公开(公告)号：JP2007131619A
公开(公告)日：2007-05-31
申请号：JP2006278658
申请日：2006-10-12
Applicant: Nisshin Pharma Inc , Sakamoto Yakuhin Kogyo Co Ltd , 日清ファルマ株式会社 , 阪本薬品工業株式会社
Inventor： MINEMURA TAKESHI , KURIYAMA SHIGEHIRA , SAKAMOTO MITSUHIRO
IPC: A61K31/122 , A23K1/16 , A23K1/165 , A23L1/30 , A61K8/06 , A61K8/35 , A61K8/39 , A61K8/67 , A61K9/107 , A61K9/48 , A61K31/07 , A61K31/375 , A61K31/51 , A61K47/14 , A61P1/02 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P21/00 , A61P25/18 , A61P35/00 , A61Q5/00 , A61Q5/02 , A61Q19/00 , A61Q19/10
Abstract: PROBLEM TO BE SOLVED: To obtain a coenzyme Q10-containing active composition which has improved dispersibility of coenzyme Q10 in an aqueous liquid, excellent absorption, efficiently makes a user take coenzyme Q10 and has high safety. SOLUTION: The coenzyme Q10-containing composition comprises coenzyme Q10, polyglycerin monomyristate and 5-70 mass% of polyglycerin condensed ricinoleic acid ester. COPYRIGHT: (C)2007,JPO&INPIT
Abstract translation: 解决问题：为了获得辅酶Q10在水性液体中的分散性提高的吸收性辅助Q10的活性组合物，吸收性优异，有效地使用者服用辅酶Q10，具有高安全性。 解决方案：含辅酶Q10的组合物包含辅酶Q10，聚甘油单肉豆蔻酸酯和5-70质量％的聚甘油缩合蓖麻油酸酯。 版权所有（C）2007，JPO＆INPIT
-
公开(公告)号：JP2007106683A
公开(公告)日：2007-04-26
申请号：JP2005296730
申请日：2005-10-11
Applicant: Nisshin Pharma Inc , 日清ファルマ株式会社
Inventor： SASAKI SATOMI , YOSHIMURA MORIO , HARADA MASATAKA
Abstract: PROBLEM TO BE SOLVED: To provide a fat accumulation inhibitor and lipolysis accelerator which have the action of inhibiting new accumulation of the body fat and reducing the body fat already accumulated and is suitable for use as an obesity preventive agent or an obesity ameliorating agent. SOLUTION: The fat accumulation inhibitor and lipolysis accelerator contain a hydrolyzate of a wheat protein and is suitably used as an obesity preventing agent or an obesity ameliorating agent. COPYRIGHT: (C)2007,JPO&INPIT
Abstract translation: 要解决的问题：提供一种脂肪蓄积抑制剂和脂肪分解促进剂，其具有抑制身体脂肪的新积累和减少已累积的身体脂肪的作用，并且适合用作肥胖症预防剂或改善肥胖症 剂。 脂肪蓄积抑制剂和脂肪分解促进剂含有小麦蛋白质的水解物，适合用作肥胖症防止剂或肥胖症改善剂。 版权所有（C）2007，JPO＆INPIT
-
公开(公告)号：JP2006111550A
公开(公告)日：2006-04-27
申请号：JP2004298944
申请日：2004-10-13
Applicant: Nisshin Pharma Inc , 日清ファルマ株式会社
Inventor： MINEMURA TAKESHI
Abstract: PROBLEM TO BE SOLVED: To obtain a carnitine-containing product having a stable appearance and a stable quality, even when containing the carnitine in a high amount. SOLUTION: This carnitine-containing product is characterized by coating a carnitine-containing solid article with a shellac coating film and further with a yeast cell wall coating film. COPYRIGHT: (C)2006,JPO&NCIPI
Abstract translation: 待解决的问题：即使含有大量的肉碱也能获得具有稳定外观和质量稳定的含肉碱的产品。 解决方案：含肉碱的产品的特征在于用虫胶涂膜涂布含肉碱的固体制品，并进一步用酵母细胞壁涂膜。 版权所有（C）2006，JPO＆NCIPI
-
Patent Agency Ranking
-
公开(公告)号：JPWO2003033507A1
公开(公告)日：2005-02-03
申请号：JP2003536246
申请日：2002-10-08
Applicant: 杏林製薬株式会社 , 日清ファルマ株式会社
IPC: C07F5/02 , A61K31/69 , A61P1/04 , A61P25/00 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/02 , A61P37/06 , A61P37/08 , A61P43/00 , C07D213/75 , C07D241/20
CPC classification number: C07F5/025
Abstract: 本発明によれば、一般式[式中、XはNまたはCHであり、Rは水素原子、C1〜C6アルキル基、C3〜C7シクロアルキル基、フェニルC1〜C6アルキル基またはC3〜C6シクロアルキルC1〜C6アルキル基である]で表されるプロテアソーム阻害作用を有する新規なベンジルマロン酸誘導体が得られる。本発明の化合物は、免疫型プロテアソームを選択的に阻害し、構成型プロテアソームへの阻害が弱い、免疫抑制剤、抗炎症剤、抗アレルギー剤、自己免疫疾患治療剤、炎症性腸疾患(潰瘍性大腸炎、クローン病)などの慢性炎症性疾患治療剤、抗がん剤、神経変性疾患治療剤として有用である。
-
公开(公告)号：JP2005002005A
公开(公告)日：2005-01-06
申请号：JP2003164804
申请日：2003-06-10
Applicant: Nisshin Pharma Inc , 日清ファルマ株式会社
Inventor： MINEMURA TAKESHI , YASUHARA SATOKO
IPC: A23K1/16 , A23L1/30 , A23L1/302 , A61K9/06 , A61K9/08 , A61K9/10 , A61K9/14 , A61K9/16 , A61K9/20 , A61K9/48 , A61K31/122 , A61K31/355 , A61K47/40 , A61K47/48 , A61P3/02 , A61P9/04
CPC classification number: A61K47/6951
Abstract: PROBLEM TO BE SOLVED: To obtain a coenzyme Q 10 -containing composition having high stability of the coenzyme Q 10 irrespective of the presence of vitamins, formulable with a medicine, a quasi-drug, a food and a feed comprising various kinds of additives formulated therein, efficiently ingesting the coenzyme Q 10 and vitamins and readily ingestible even by the aged and persons difficult to swallow. SOLUTION: This coenzyme Q 10 -containing composition comprises the coenzyme Q 10 and the vitamins. In the composition, at least one of the coenzyme Q 10 and the vitamins is included with cyclodextrin. COPYRIGHT: (C)2005,JPO&NCIPI
Abstract translation: 待解决的问题：为了获得具有高稳定性的辅酶Q SB <10S / SB>的辅酶Q <10> / SB>组合物，无论是否存在维生素，可用药物 ，准药物，食品和包含各种添加剂的饲料，有效摄取辅酶Q SB和维生素，即使老年人和难以吞咽的人也容易摄取。 解决方案：这种含辅酶Q 10 SB组合物包含辅酶Q SB 10和维生素。 在组合物中，环糊精中包含至少一种辅酶Q SB 10和维生素。 版权所有（C）2005，JPO＆NCIPI
-
公开(公告)号：JP2004196781A
公开(公告)日：2004-07-15
申请号：JP2003395033
申请日：2003-11-26
Applicant: Nisshin Pharma Inc , Nof Corp , 日本油脂株式会社 , 日清ファルマ株式会社
Inventor： SEGAWA TAKEFUMI , ABE ATSUKO , MINEMURA TAKESHI , KUBOTA HIROTAKA
IPC: A23K1/16 , A23L1/30 , A23L1/302 , A61K8/02 , A61K8/19 , A61K8/30 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/72 , A61K8/73 , A61K31/122 , A61K47/04 , A61K47/10 , A61K47/14 , A61K47/34 , A61K47/36 , A61K47/44 , A61P3/02 , A61P9/00 , A61P17/00 , A61P37/02 , A61P39/06 , A61K7/00
Abstract: PROBLEM TO BE SOLVED: To obtain a water-soluble composition containing coenzyme Q 10 , free from the deposition, precipitation or flotation of the coenzyme Q 10 formulated in a high concentration without using a dissolution medium such as oil-and-fat, keeping a homogeneous and stable dissolved (solubilized) state, having excellent acid resistance, salt resistance and heat resistance necessary as an additive for pharmaceuticals, food products, drink products, cosmetics and feeds and having remarkably improved absorbability in the body, and provide a method for the production of the composition. SOLUTION: This water-soluble composition containing coenzyme Q 10 is composed of (A) 5-40 mass% coenzyme Q 10 , (B) 5-30 mass% monoester of a polyglycerol having an average polymerization degree of 10 and an 18C fatty acid, (C) 1-18 mass% mono-, di-, tri- or penta-ester of a polyglycerol having an average polymerization degree of 3-6 and an 18C fatty acid, (D) water and optionally (E) 10-80 mass% solubilizing assistant. The composition has an average particle diameter of ≤110 nm. COPYRIGHT: (C)2004,JPO&NCIPI
-
-
-
-
-
-
-
-
-
Search Results
246
records
(took 0.039 seconds)
