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公开(公告)号:JP2004035562A
公开(公告)日:2004-02-05
申请号:JP2003271646
申请日:2003-07-07
申请人: Genitope Corp , ジェニトープ コーポレーション
发明人: DENNEY JR DAN W
IPC分类号: C12N15/09 , A61K39/00 , A61K39/395 , A61P35/00 , A61P35/02 , A61P37/02 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/725 , C07K14/74 , C07K16/00 , C07K16/18 , C12N1/15 , C12N1/19 , C12N5/10 , C12N9/00 , C12N9/06 , C12N15/85
CPC分类号: C12N9/003 , A61K39/395 , A61K2039/505 , C07K14/52 , C07K14/5428 , C07K14/7051 , C07K14/70539 , C07K14/70596 , C07K16/00 , C07K2319/00 , C12N9/00 , C12N15/85 , C12N2840/20 , C12N2840/44
摘要: PROBLEM TO BE SOLVED: To provide a polyvalent vaccine for treating B-cell malignant diseases (for example, lymphoma and leukemia). SOLUTION: This polyvalent vaccine has at least two recombining variable regions of an immunoglobulin molecule derived from a B-cell lymphoma cell of a single patient, wherein the cell expresses at least two immunoglobulin molecules which are different from each other, and the immunoglobulin molecules are different in at least one idiotope. COPYRIGHT: (C)2004,JPO
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公开(公告)号:JP2007252385A
公开(公告)日:2007-10-04
申请号:JP2007136658
申请日:2007-05-23
申请人: Genitope Corp , ジェニトープ コーポレーション
发明人: DENNEY JR DAN W
IPC分类号: C12N15/09 , C12P21/02 , A61K39/00 , A61K39/395 , A61P35/00 , A61P35/02 , A61P37/02 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/725 , C07K14/74 , C07K16/00 , C07K16/18 , C12N1/15 , C12N1/19 , C12N5/10 , C12N9/00 , C12N9/06 , C12N15/85
CPC分类号: C12N9/003 , A61K39/395 , A61K2039/505 , C07K14/52 , C07K14/5428 , C07K14/7051 , C07K14/70539 , C07K14/70596 , C07K16/00 , C07K2319/00 , C12N9/00 , C12N15/85 , C12N2840/20 , C12N2840/44
摘要: PROBLEM TO BE SOLVED: To provide multivalent vaccines for treating B-cell malignancies (e.g., lymphomas and leukemias). SOLUTION: The multivalent vaccines have at least two recombinant variable regions of immunoglobulin molecules derived from B-cell lymphoma cells of a single patient, wherein the cells exhibit two different immunoglobulin molecules and the immunoglobulin molecules are different based on at least one idiotope. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译: 待解决的问题:提供治疗B细胞恶性肿瘤(例如淋巴瘤和白血病)的多价疫苗。 解决方案:多价疫苗具有衍生自单个患者的B细胞淋巴瘤细胞的免疫球蛋白分子的至少两个重组可变区,其中所述细胞表现出两种不同的免疫球蛋白分子,并且所述免疫球蛋白分子基于至少一种特异性 。 版权所有(C)2008,JPO&INPIT
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公开(公告)号:JP2007277266A
公开(公告)日:2007-10-25
申请号:JP2007189291
申请日:2007-07-20
申请人: Genitope Corp , ジェニトープ コーポレーション
发明人: DENNEY JR DAN W
IPC分类号: A61K39/00 , C12N15/09 , A61K39/39 , A61K39/395 , A61P35/00 , A61P35/02 , A61P37/02 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/725 , C07K14/74 , C07K16/00 , C07K16/18 , C12N1/15 , C12N1/19 , C12N5/10 , C12N9/00 , C12N9/06 , C12N15/85
CPC分类号: C12N9/003 , A61K39/395 , A61K2039/505 , C07K14/52 , C07K14/5428 , C07K14/7051 , C07K14/70539 , C07K14/70596 , C07K16/00 , C07K2319/00 , C12N9/00 , C12N15/85 , C12N2840/20 , C12N2840/44
摘要: PROBLEM TO BE SOLVED: To provide a polyvalent vaccine for treating B-cell malignant diseases (for example, lymphoma and leukemia). SOLUTION: This polyvalent vaccine has at least two recombining variable regions of an immunoglobulin molecule derived from a B-cell lymphoma cell of a single patient, wherein the cell expresses at least two immunoglobulin molecules different from each other, and the immunoglobulin molecules are different in at least one idiotope. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译: 待解决的问题:提供治疗B细胞恶性疾病(例如淋巴瘤和白血病)的多价疫苗。 解决方案:该多价疫苗具有至少两个衍生自单个患者的B细胞淋巴瘤细胞的免疫球蛋白分子的重组可变区,其中细胞表达至少两个彼此不同的免疫球蛋白分子,免疫球蛋白分子 在至少一个独特的人物上是不同的。 版权所有(C)2008,JPO&INPIT
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