利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

14 条记录 (耗时 0.018 秒)

    Antiallergic agent
    2.
    发明专利
    Antiallergic agent 有权
    抗真菌剂

    公开(公告)号：JP2004067567A

    公开(公告)日：2004-03-04

    申请号：JP2002227714

    申请日：2002-08-05

    申请人： Hitoshi Nagaoka ,  長岡 均

    发明人： NAGAOKA HITOSHI

    IPC分类号： A23L1/30 ,  A61K36/07 ,  A61P17/00 ,  A61P37/08 ,  A61K35/84

    摘要： PROBLEM TO BE SOLVED: To obtain a health food or a medicine which prevents and treats allergic symptoms, especially atopic dermatitis and has excellent safety. SOLUTION: The antiallergic agent, especially the antiallergic agent for atopic dermatitis comprises mycelium essence extracted from a mycelium culture of Basidiomycetes. The mycelium essence of Basidiomycetes is preferably mycelium essence of a basidiomycete which is obtained by inoculating the basidiomycete into a solid medium composed of bagasse as a base, then proliferating the mycelium to give a mycelium-containing solid medium, untying the solid medium, adding water and one or more kinds of enzymes selected from cellulase and protease to the untied solid medium while keeping the solid medium at 30-50°C, grinding and mashing the solid medium in the presence of the enzyme to extract the mycelium essence of the basidiomycete, then deactivating the enzyme and sterilizing the essence by heating the essence to 95°C. Lentinula edodes, Hericium erinaceum or Flammulina Velutipes is preferable as the basidiomycete. COPYRIGHT: (C)2004,JPO

    摘要翻译： 要解决的问题：获得预防和治疗过敏症状的保健食品或药物，特别是特应性皮炎，并且具有优异的安全性。 解毒剂：抗过敏剂，特别是特应性皮炎的抗过敏剂包括从担子菌的菌丝体培养物中提取的菌丝体精华。 担子菌的菌丝体本质优选是担子菌的菌丝体本体，其通过将担子菌接种到由甘蔗渣为基础的固体培养基中，然后增殖菌丝体得到含菌丝体的固体培养基，取出固体培养基，加水 以及一种或多种选自纤维素酶和蛋白酶的酶到未固化的固体培养基，同时保持固体培养基在30-50℃，在酶存在下研磨和糖化固体培养基以提取担子菌的菌丝体精华， 然后停用酶并通过将精华加热至95℃来灭菌精华。 香菇，龙舌兰（Hericium erinaceum）或Flammulina Velutipes作为担子菌是优选的。 版权所有（C）2004，JPO

    Immunoactivity modulator containing extract of mycelium of basidiomycetes
    3.
    发明专利
    Immunoactivity modulator containing extract of mycelium of basidiomycetes 审中-公开
    含有碱性蛋白质提取物的免疫调节剂

    公开(公告)号：JP2002371004A

    公开(公告)日：2002-12-26

    申请号：JP2001177646

    申请日：2001-06-12

    申请人： Hitoshi Nagaoka ,  長岡 均

    发明人： NAGAOKA HITOSHI

    IPC分类号： A23L1/28 ,  A23L1/30 ,  A61K36/07 ,  A61P35/00 ,  A61P37/02 ,  A61P43/00 ,  A61K35/84

    摘要： PROBLEM TO BE SOLVED: To obtain an immunoactivity modulator, especially one against an immunocyte. SOLUTION: This immunoactivity modulator is characterized in that the modulator comprises extracts of mycelia of Basidiomycetes extracted from mycelia cultures of Cortinellus shiitake, bracket fungus of the genus Fomes and Flammulina velutipes. When the total amount of the extracts having modulation ability against immunoactivity is 100%, the modulator comprises 40-80 wt.% of the extract of mycelium of Cortinellus shiitake, 10-30 wt.% of the extract of mycelium of bracket fungus of the genus Fomes and 10-30 wt.% of the extract of mycelium of Flammulina velutipes.

    摘要翻译： 要解决的问题：获得免疫活性调节剂，特别是针对免疫细胞的调节剂。 解决方案：该免疫活性调节剂的特征在于，该调节剂包括从壳聚糖菌丝菌丝菌菌丝菌属（Fortes）和火菇菌属（Flammulina velutipes）的菌丝体培养物中提取的担子菌菌丝体提取物。 当具有针对免疫活性的调节能力的提取物的总量为100％时，调节剂包含40-80重量％的Cortinellus shiitake菌丝体提取物，10-30重量％的支架真菌菌丝体提取物 属的Fomes和10-30重量％的Flammulina velutipes的菌丝体提取物。

    Hepatic fibrosis inhibitory agent
    4.
    发明专利
    Hepatic fibrosis inhibitory agent 审中-公开
    肝纤维化抑制剂

    公开(公告)号：JP2005239699A

    公开(公告)日：2005-09-08

    申请号：JP2004093129

    申请日：2004-03-26

    申请人： Kobayashi Pharmaceut Co Ltd ,  Nagaoka Hitoshi ,  小林製薬株式会社 ,  長岡 均

    发明人： YAGI KIYOHITO ,  KAWASE MASAYA ,  WATANABE AIKO ,  TAMESADA MAKOTO

    IPC分类号： A23L1/30 ,  A61K31/05 ,  A61K36/07 ,  A61P1/16 ,  A61P31/12 ,  A61P35/00 ,  A61K35/84

    CPC分类号： A61K31/05 ,  A23L33/10 ,  A61K36/07

    摘要： PROBLEM TO BE SOLVED: To provide an effective preventing or treating means for hepatic fibrosis, and also to obtain a hepatic fibrosis inhibitory agent capable of becoming the treating means, a medicinal composition, a food and drink. SOLUTION: This hepatic fibrosis inhibitory agent contains a shiitake mushroom (Lentinus edodes) mycelia extract or its fractionated substance. A hepatic protecting agent having the effect of inhibiting the hepatic fibrosis contains the shiitake mushroom mycelia extract or its fractionated substance. Also, the medicinal composition, food, beverage, and the like, containing the fractionated substance are provided. COPYRIGHT: (C)2005,JPO&NCIPI

    摘要翻译： 要解决的问题：提供肝纤维化的有效预防或治疗手段，以及获得能够成为治疗手段的肝纤维化抑制剂，药物组合物，食品和饮料。 解决方案：该肝纤维化抑制剂含有香菇（Lentinus edodes）菌丝体提取物或其分馏物质。 具有抑制肝纤维化作用的肝保护剂含有香菇菌丝体提取物或其分馏物。 此外，还提供含有分级物质的药物组合物，食品，饮料等。 版权所有（C）2005，JPO＆NCIPI

    Skin whitening agent
    7.
    发明专利
    Skin whitening agent 审中-公开
    皮肤白化剂

    公开(公告)号：JP2003048821A

    公开(公告)日：2003-02-21

    申请号：JP2001236155

    申请日：2001-08-03

    申请人： Hitoshi Nagaoka ,  長岡 均

    发明人： NAGAOKA HITOSHI

    IPC分类号： A23L2/38 ,  A23L1/28 ,  A23L2/52 ,  A61K8/00 ,  A61K8/96 ,  A61K8/97 ,  A61K36/07 ,  A61P17/16 ,  A61Q19/00 ,  A61K7/48 ,  A61K7/00 ,  A61K35/84

    摘要： PROBLEM TO BE SOLVED: To provide a skin whitening agent which contains a Cortinellus shiitake mycelium extract and utilizes a skin whitening action of the Cortinellus shiitake mycelium extract. SOLUTION: This skin whitening agent contains the Cortinellus shiitake mycelium extract. The Cortinellus shiitake mycelium extract is obtained by inoculating Cortinellus shiitake mycelia in a solid culture medium containing bagasse as a main material, proliferating the mycelia, untying the obtained mycelium-containing solid culture medium, adding water and at least one enzyme selected from cellulase, glucosidase, and protease at 30 to 50 deg.C, crushing and mashing the solid culture medium in the presence of the added enzyme to extract L.E.M, and then heating the L.E.M at a temperature up to 95 deg.C to inactivate and sterilize the enzyme. The skin whitening agent may be used even in any of forms for an external application and internal application, is effective for maintaining the beauty and health of skins, does not produce a side effect, and is therefore excellent from the aspect of safety.

    摘要翻译： 要解决的问题：提供一种皮肤增白剂，其含有皮质丝状菌丝体提取物，并利用皮质丝状菌丝体提取物的皮肤美白作用。 解决方案：这种皮肤美白剂含有皮质绦虫菌丝体提取物。 通过将Cortinellus shiitake菌丝体接种在含有甘蔗渣的固体培养基中作为主要物质，增殖菌丝体，取出所获得的含有菌丝体的固体培养基，加入水和至少一种选自纤维素酶，葡糖苷酶的酶，得到Cortinellus shiitake菌丝体提取物 ，蛋白酶30〜50℃，在添加的酶的存在下对固体培养基进行破碎和糖化，提取LEM，然后在高达95℃的温度下加热LEM以使酶失活和灭菌。 皮肤美白剂即使在任何形式的外用和内用的情况下都可以使用，对于保持皮肤的美丽和健康是有效的，不会产生副作用，因此从安全性方面来说是优异的。