公开(公告)号：JPH07145059A

公开(公告)日：1995-06-06

申请号：JP18141394

申请日：1994-08-02

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： FUERENKU ENDAA ,  YOSEFU FURESU ,  RAAZURO ROSHIBAARU ,  KATARIN SHIYUBAIZAA

IPC: C07D473/08 ,  A61K9/08 ,  A61K9/22 ,  A61K9/48 ,  A61K31/52 ,  A61K31/522 ,  A61P17/00 ,  A61P43/00 ,  C07D473/10

Abstract: PURPOSE: To promote a healing process of anastomosis by improving a tissue anti-oxidative status while retaining excellent inhibitory effect on the adhesion of anastomosis. CONSTITUTION: A pharmaceutical composition containing 3,7-dihydroxy-3,7- dimethyl-1-(5-oxohexyl)-1H-purin-2,6-dione and/or 1-(3',4'-diethoxybenzyl)-6,7- diethoxy-3,4-dihydroisoquinolinium theophylline-7-acetate, or its monohydrate as an active ingredient is used for the promotion of a healing process of anastomosis.

公开(公告)号：JPH06145058A

公开(公告)日：1994-05-24

申请号：JP13553492

申请日：1992-04-10

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： ZORUTAN KAPUI ,  ISUTOBAN HERUMEKUTSU ,  RASUZURO TARUDOSU ,  KATARIN MARUMAROSHI NE KERUNAA ,  RERURE BUASUBUARI NE DEBUREKUJ ,  AGUNESU HORUBASU

IPC: A61K31/47 ,  A61K31/485 ,  A61K31/52 ,  A61P7/02 ,  A61P9/08 ,  A61P9/10 ,  A61P17/00

Abstract: PURPOSE: To obtain a medicinal compsn. for treating or preventing symptoms due to increased platelet aggregation activity as the result of reduction of release of prostacyclin. CONSTITUTION: This medicinal compsn. contains 1-(3',4'-dimethoxybenzyl)-6,7- dimethoxyisoquinoline,1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydr oisoquinoline, (3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium theophylline-7-acetate or its monohydrate as an active component.

公开(公告)号：JPH06128152A

公开(公告)日：1994-05-10

申请号：JP9568192

申请日：1992-04-15

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： ANNA ZEE SABOO ,  GABURIETSURA SABOO NEE UIHEII ,  ANTARU TOOCHI ,  TAMAASHIYU SHIYUCHI ,  KAARUMAAN MAJIYARU ,  YOOJIEFU RENJIERU ,  YAANOSHIYU PINTEERU ,  ANNA SEEKEI ,  ANDORAASHIYU SEGEE ,  KATARIN MAARUMAROSHI NEE KERUN

IPC: A61K9/70 ,  A61K9/06 ,  A61K9/127 ,  A61K31/13 ,  A61K31/135 ,  A61K31/75 ,  A61K47/10 ,  A61K47/34 ,  A61L15/16 ,  A61M37/00 ,  A61P17/00 ,  C08L71/02

Abstract: PURPOSE: To obtain an anhydrous percutaneous compsn. contg. an active component and auxiliary materials in a lyotropic liq. crystal structure. CONSTITUTION: This anhydrous percutaneous compsn. contains 5-15 wt.% optically active or racemic N-methyl-N-(phenyl-2-propyl)-2-propynylamine or N- methyl-N-[1-(4-fluorophenyl)-2-propyl]-2-propynylamine or its therapeutically suitable salt, 40-70 wt.% liq. polyoxyethylene, 10-20 wt.% solid polyoxyethylene, 2-30 wt.% nonionic surfactant and 2-20 wt.% propylene glycol in 20-100% lyotropic liq. crystal structure or further contains 0.5-2 wt.% polymer (a value >0.6) and such an amt. of other auxiliary as an emulsifier as to attain 100 wt.%.

公开(公告)号：JPH05201949A

公开(公告)日：1993-08-10

申请号：JP12686591

申请日：1991-04-30

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： GIYORUGII HIDASHI ,  ISUTOBAN SUZEKERII ,  BERA BERUTOTSUKU ,  SANDOORU ZORUTAN ,  RAYOSU NAGII ,  ANTARU GAYARI ,  EBA SOMUFUEI ,  AGUNESU HEGEJIYUUSU ,  RASUZURO PATSUPU ,  RUDORUFU SOOSU ,  ERUZUSEBETSUTO RADOBANII ,  SANDOORU BOTARU ,  TAMASU SUZABORUKUSHI

IPC: C07C69/747 ,  A01N20060101 ,  A01N37/34 ,  A01N53/00 ,  A01N53/08 ,  A01P7/04 ,  C07B20060101 ,  C07B57/00 ,  C07B61/00 ,  C07B63/04 ,  C07C20060101 ,  C07C67/52 ,  C07C69/743 ,  C07C253/30 ,  C07C253/34 ,  C07C255/00 ,  C07C255/37 ,  C07C255/39

公开(公告)号：JPH02184629A

公开(公告)日：1990-07-19

申请号：JP28728489

申请日：1989-11-02

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： PEETERU SENTOMIKUROOSHI ,  TAMAASHIYU SHIYUCHI ,  JIERUJI HIDASHI ,  ISHIYUTOBAAN YUHAASU

IPC: C07H17/08 ,  A61K8/00 ,  A61K8/34 ,  A61K8/44 ,  A61K8/49 ,  A61K8/60 ,  A61K9/08 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61K47/10 ,  A61K47/18 ,  A61K47/22 ,  A61K47/48 ,  A61P17/00 ,  A61P31/04

Abstract: PURPOSE: To prepare an aqueous solution, transparent and stable even after cooling and useful as a pharmaceutical and a cosmetic compositions by thermally mixing a salt of primycin with an adequate amount of pyroglutamic acid in isopropanol, diluting the prepared mixture with water and then stirring the resultant diluted solution under heating. CONSTITUTION: This stable aqueous solution of primycin is prepared by suspending primycin sulfate in an amount of 0.5-1.75% (wt./vol.) based on the volume of the solution to be prepared or a complex of the primycin in an amount of 2.5-9% (wt./vol.) based on the volume of the solution to be prepared with N-methylpyrrolidone and pyroglutamic acid (preferably L-glutamic acid) or its soluble salt (especially Na salt) in an amount of 2-15% (wt./vol.) based on the volume of the solution to be prepared in isopropanol in a volume of 40-60vol.% based on the volume of the solution to be prepared under stirring and heating (preferably at 40-60 deg.C), diluting the resultant mixture to a desired concentration with water and stirring and cooling the obtained emulsionlike suspension. A complex containing 20wt.% primycin with the N- methylpyrrolidone is preferably used.

公开(公告)号：JPH01213266A

公开(公告)日：1989-08-28

申请号：JP33567888

申请日：1988-12-28

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： ENDORE PAAROSHI ,  DEJIEE KORUBONICHI ,  ERUJIEEBETO MORUNAARU NEE BAKO ,  IDA SUBOBODA NEE KANZERU ,  RAASUROO HAARUSHINGU ,  JIERUJI SHIMON ,  BERA GERUGERII ,  PEETERU KERUMETSUI ,  SHIYAANDORU BIRAAGU ,  KATARIN MAARUMAROSHI NEE KERUN

IPC: A61K31/47 ,  A61K31/472 ,  A61P7/10 ,  A61P9/02 ,  C07D217/08

公开(公告)号：JPS6490106A

公开(公告)日：1989-04-06

申请号：JP17685988

申请日：1988-07-15

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： TAMASU DETORE ,  SANDOORU ANGUYAN ,  RASUZURO PATSUPU ,  ANDORASU SUZEGO ,  ZORUTAN KARADEI ,  KURARA BERUTSUSU NE BENDE ,  KATARIN MARUMAROSHI NE KERUNAA

IPC: A01N33/18 ,  A01N25/02 ,  A01N25/04 ,  A01N33/22 ,  A01N37/26 ,  A01N43/12 ,  A01N43/60 ,  A01N43/653 ,  A01N43/80 ,  A01N43/90 ,  A01N47/18 ,  A01N47/22 ,  A01N47/30 ,  A01N47/34 ,  A01N47/36 ,  A01N47/38 ,  A01N57/14 ,  A01N57/16 ,  A01P13/00

Abstract: PURPOSE: To prepare a plant-protecting solution which contains an insoluble plant-protecting component, a specific water-miscible solvent and a partially water-miscible solvent and a specific additive in a specific proportion, is crystalline at room temperature, has a solubility of

公开(公告)号：JPS62181217A

公开(公告)日：1987-08-08

申请号：JP27988786

申请日：1986-11-26

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： SZENTMIKLOSI PETER ,  SZUETS TAMAS ,  NEMES JOZSEF ,  LENGYEL JOZSEF ,  MARTON JENOE ,  BABOS NEE VAJAS ERZSEBET ,  SCHREINER NEE KOVATS ENIKOE ,  SARKOEZI PETER

IPC: A61K8/49 ,  A61K8/02 ,  A61K8/42 ,  A61K8/60 ,  A61K9/08 ,  A61K31/155 ,  A61K31/70 ,  A61K47/00 ,  A61K47/32

公开(公告)号：JPS61280492A

公开(公告)日：1986-12-11

申请号：JP11497386

申请日：1986-05-21

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： SHIRUBUESUTERU BUIJI ,  CHIYABA SAANTAI ,  RAJIYOSHIYU SABOO ,  ISHIYUTOBUAAN TOOSU ,  GAABORU KOBUAACHIYU ,  IENOEE MARUTON ,  RAASUROO HAARUSHINGU ,  JIYOORUJII SOMOJII ,  YOOJIEFU GAARU

IPC: C07D453/00 ,  A61K31/435 ,  A61K31/47 ,  A61P25/02 ,  A61P25/24 ,  A61P25/26 ,  A61P31/04 ,  C07D215/56 ,  C07D237/28 ,  C07D401/04 ,  C07D455/02 ,  C07D455/03 ,  C07D471/04

公开(公告)号：JPS61275202A

公开(公告)日：1986-12-05

申请号：JP4716386

申请日：1986-03-04

Applicant: CHINOIN GYOGYSZER ES VEGYESZET

Inventor： STRUMPF THOMAS ,  LYR HORST ,  ZANKE DIETER ,  ZOLLFRANK GERLINE ,  OROS GYULA ,  VIRANYI FERENC ,  ERSEK TIBOR

IPC: A01N37/46 ,  A01N43/08 ,  A01N43/76 ,  A01N43/84 ,  A01N53/00 ,  A01P3/00