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    Hot-water extract from white to yellow deer-horn ganoderma lucidum, and cosmetics, health food and anticancer drug each comprising the same
    2.
    发明专利
    Hot-water extract from white to yellow deer-horn ganoderma lucidum, and cosmetics, health food and anticancer drug each comprising the same 审中-公开
    从白色至黄酮的热水提取物，以及化妆品，健康食品和包含其中的抗生素药物

    公开(公告)号：JP2010043017A

    公开(公告)日：2010-02-25

    申请号：JP2008207610

    申请日：2008-08-12

    申请人： Toshiyuki Ishikawa ,  Kisotec:Kk ,  Tomoyuki Nakamura ,  友幸 中村 ,  株式会社キソテック ,  敏幸 石川

    发明人： ISHIKAWA TOSHIYUKI ,  HIGASHIYAMA YOSHIRO ,  NAKAMURA TOMOYUKI ,  OGISO YASUO ,  OGISO YOSHIYASU

    IPC分类号： C07G99/00 ,  A01G1/04 ,  A01N1/02 ,  A23L1/30 ,  A61K8/97 ,  A61K36/07 ,  A61P35/00 ,  A61P39/06 ,  A61P43/00 ,  A61Q19/02

    摘要： PROBLEM TO BE SOLVED: To provide a hot-water extract comprising a substance having a physiological activity to humans, obtained from a fruit body of white to yellow Ganoderma lucidum, and cosmetics, health food and an anticancer drug each comprising the same.
    SOLUTION: Disclosed are, (1) a hot-water extract comprising a substance having physiological activity to humans, obtained from a fruit body of white to yellow Ganoderma lucidum, (2) a hot-water extract according to (1), wherein the substance having physiological activity to humans has a growth-promotion action on a normal human fibroblast (NB1RGB), (3) a hot-water extract according to (1), wherein the substance having physiological activity to humans has a tyrosinase inhibitory action, (4) a hot-water extract according to (1), wherein the substance having physiological activity to humans has an antioxidative action, (5) a hot-water extract according to (1), wherein the substance having physiological activity to humans has an antitumor effect, and (6) health food of low bitterness hardly containing ganoderic acid or the like and comprising the above hot-water extracts.
    COPYRIGHT: (C)2010,JPO&INPIT

    摘要翻译： 待解决的问题：提供一种包含从白色至黄色灵芝的果实体获得的具有对人类具有生理活性的物质的热水提取物，以及各自包含其的化妆品，保健食品和抗癌药物 。 解决方案：公开了（1）从白色至黄色灵芝的果实体获得的包含对人体具有生理活性的物质的热水提取物，（2）根据（1）的热水提取物， 其特征在于，对人体具有生理活性的物质对正常人成纤维细胞（NB1RGB）具有生长促进作用，（3）根据（1）所述的热水提取物，其中，对人体具有生理活性的物质具有抑制酪氨酸酶 （4）根据（1）的热水提取物，其中对人体具有生理活性的物质具有抗氧化作用，（5）根据（1）所述的热水提取物，其中，具有生理活性的物质 人类具有抗肿瘤作用，（6）低苦味的保健食品几乎不含有甘油酸等，并且包含上述热水提取物。 版权所有（C）2010，JPO＆INPIT

    Cultivation method of ornamental white or yellow ganoderma lucidum
    4.
    发明专利
    Cultivation method of ornamental white or yellow ganoderma lucidum 有权
    白藜芦醇或黄黄芪粉的制备方法

    公开(公告)号：JP2008228674A

    公开(公告)日：2008-10-02

    申请号：JP2007074081

    申请日：2007-03-22

    申请人： Toshiyuki Ishikawa ,  Kisotec:Kk ,  Tomoyuki Nakamura ,  友幸 中村 ,  株式会社キソテック ,  敏幸 石川

    发明人： ISHIKAWA TOSHIYUKI ,  HIGASHIYAMA YOSHIRO ,  NAKAMURA TOMOYUKI ,  OGISO YASUO ,  OGISO YOSHIYASU

    IPC分类号： A01G1/04

    摘要： PROBLEM TO BE SOLVED: To provide a mushroom bed cultivation method of ornamental Ganoderma lucidum which has appearance completely different from that of conventional Ganoderma lucidum and presents a white or yellow stag horn.
    SOLUTION: This mushroom bed cultivation method of ornamental white or yellow Ganoderma lucidum is performed in a housing and comprises inoculating hypha of Ganoderma lucidum to a mushroom bed followed by growing thick, storing the mushroom bed in a housing followed by holding, and keeping the housing in (A)-(C) conditions and raising carpophore of Ganoderma lucidum. (A) To cover the upper part of the housing with a semi-translucent material so as to bring a transmission rate to 65-85% until Ganoderma lucidum passes through bud cutting (sprouting) and infant Ganoderma lucidum starts to change color, after storing the mushroom bed in the housing. (B) To densely cover the upper surface of the housing with a shading material so as to increase airtightness and completely block light before the infant Ganoderma lucidum changes color to blackish brown after bud cutting. (C) To adjust a temperature in space of the housing to 25-35°C, and humidity to ≥90% and retain the condition.
    COPYRIGHT: (C)2009,JPO&INPIT

    摘要翻译： 要解决的问题：提供具有与常规灵芝的外观完全不同的装饰灵芝的蘑菇床栽培方法，并呈现白色或黄色雄蕊。

    解决方案：在房屋中进行装饰性白色或黄色灵芝的蘑菇床栽培方法，包括将灵芝菌丝接种到蘑菇床上，随后生长厚，将蘑菇床存放在壳体中，然后保持， 将住房保留在（A） - （C）条件下，并提高灵芝的栖息地。 （A）以半透明材料覆盖外壳的上部，使透射率达到65-85％，直到灵芝通过芽切（发芽），灵芝开始改变颜色，储存后 蘑菇床在房子里。 （B）用遮光材料密集地覆盖住房屋的上表面，以便在芽灵切割后，灵芝灵芝变成黑褐色之前，增加气密性并完全阻挡光线。 （C）将外壳空间温度调节至25-35℃，湿度≥90％，并保持状态。 版权所有（C）2009，JPO＆INPIT

    Cultivation method of decorative white or yellow ganoderma lucidum
    5.
    发明专利
    Cultivation method of decorative white or yellow ganoderma lucidum 有权
    装饰性白色或黄色甘蔗粉的制作方法

    公开(公告)号：JP2008154463A

    公开(公告)日：2008-07-10

    申请号：JP2006343664

    申请日：2006-12-21

    申请人： Toshiyuki Ishikawa ,  Kisotec:Kk ,  Tomoyuki Nakamura ,  友幸 中村 ,  株式会社キソテック ,  敏幸 石川

    发明人： ISHIKAWA TOSHIYUKI ,  HIGASHIYAMA YOSHIRO ,  NAKAMURA TOMOYUKI ,  OGISO YASUO ,  OGISO YOSHIYASU

    IPC分类号： A01G1/04

    摘要： PROBLEM TO BE SOLVED: To provide a cultivation method of decorative Ganoderma lucidum having completely different appearance from conventional Ganoderma lucidum and showing white or yellow deer horn. SOLUTION: This artificial cultivation method of the decorative white or yellow Ganoderma lucidum, to be performed in a housing comprises inoculating hypha of Ganoderma lucidum to cut shiitake log of broadleaf tree followed by growing thick, burying the cut shiitake log into soil in the housing to an extent allowing to see the cut surface, and maintaining the housing to grow carpophore of Ganoderma lucidum in (A)-(C) conditions as follows. (A) Until young Ganoderma lucidum starts to change color, passing from burying to sprouting, the upper part of the housing is covered with a semi-translucent object so as to bring a transmission rate to 65-85%. (B) Before the young Ganoderma lucidum changes to a blackish brown color after cutting buds, the upper surface of the housing is densely covered with a shade material so as to increase airtightness and completely block light. (C) A temperature in space of the housing is adjusted to 25-35°C and a relative humidity, to ≥90% and the condition is maintained. COPYRIGHT: (C)2008,JPO&INPIT

    摘要翻译： 要解决的问题：提供具有与常规灵芝完全不同外观的灵芝装饰物的培养方法，并显示白色或黄色鹿角。

    解决方案：在房屋中进行的装饰性白色或黄色灵芝的人工培养方法包括接种灵芝菌丝以切开阔叶树的日本原木，然后生长较厚，将切成的香菇木埋入土壤中 在（A） - （C）条件下，房屋在一定程度上允许看到切割表面，并保持房屋在灵芝中生长灵芝。 （A）直到灵芝开始改变颜色，从掩埋过渡到发芽，房屋的上部被半透明物体覆盖，使透射率达到65-85％。 （B）青春灵芝在切芽后变成黑褐色，壳体的上表面被密封地覆盖着遮光材料，从而增加气密性并完全阻挡光线。 （C）将壳体的空间温度调节至25-35℃，相对湿度≥90％，并保持状态。 版权所有（C）2008，JPO＆INPIT

    Cyathane derivative and antibacterial agent containing the derivative as active component
    7.
    发明专利
    Cyathane derivative and antibacterial agent containing the derivative as active component 有权
    含有衍生物作为活性成分的氰基衍生物和抗菌剂

    公开(公告)号：JP2005239669A

    公开(公告)日：2005-09-08

    申请号：JP2004053849

    申请日：2004-02-27

    申请人： Yukito Akiyama ,  Hirokazu Kawagishi ,  Tomoyuki Nakamura ,  友幸 中村 ,  洋和 河岸 ,  幸仁 秋山

    发明人： KAWAGISHI HIROKAZU ,  NAKAMURA TOMOYUKI ,  AKIYAMA YUKITO ,  TOKUYAMA SHINJI

    IPC分类号： C07H7/06 ,  A61K36/07 ,  A61P31/04 ,  A61K35/84

    CPC分类号： Y02A50/473

    摘要： PROBLEM TO BE SOLVED: To provide a cyathane derivative (named as erinacineJ) and an antibacterial agent containing the derivative as an active component, especially an antibacterial agent effective against MRSA (methicillin resistant Staphylococcus aureus). SOLUTION: The invention provides (1) a cyathane derivative expressed by structural formula, (2) an antibacterial agent containing the cyathane derivative as an active component and (3) an antibacterial agent for MRSA containing the cyathane derivative as an active component. COPYRIGHT: (C)2005,JPO&NCIPI

    摘要翻译： 要解决的问题：提供一种细胞因子衍生物（命名为erinacineJ）和含有该衍生物作为活性成分的抗菌剂，特别是抗MRSA（耐甲氧西林金黄色葡萄球菌）的抗菌剂。 解决方案：本发明提供（1）由结构式表示的星形衍生物衍生物，（2）含有胞苷衍生物作为活性成分的抗菌剂，（3）含有胞苷衍生物作为活性成分的MRSA抗菌剂 。 版权所有（C）2005，JPO＆NCIPI

    Histamine release inhibitor and method for producing the same
    8.
    发明专利
    Histamine release inhibitor and method for producing the same 审中-公开

    公开(公告)号：JP2004168689A

    公开(公告)日：2004-06-17

    申请号：JP2002335238

    申请日：2002-11-19

    申请人： Yukito Akiyama ,  Tomoyuki Nakamura ,  友幸 中村 ,  幸仁 秋山

    发明人： KOMAI KOICHIRO ,  NAKAMURA TOMOYUKI ,  AKIYAMA YUKITO ,  KASUGA IKUYO

    IPC分类号： A61K36/07 ,  A61P43/00 ,  A61K35/84

    摘要： PROBLEM TO BE SOLVED: To obtain a histamine release inhibitor on the basis of knowledge that a substance derived from a mycelium of Phellinus linteus has inhibitory action on histamine release, and to provide a method for producing the same. SOLUTION: (1) The histamine release inhibitor comprises the substance derived from the mycelium of Phellinus linteus. (2) The histamine release inhibitor comprises an extract of Phellinus linteus with hot water. (3) The histamine release inhibitor comprises a methanol-soluble fraction in the extract of Phellinus linteus with hot water. (4) The histamine release inhibitor comprises a methanol-eluted fraction of the methanol-soluble fraction in the extract of Phellinus linteus with hot water adsorbed on an ion adsorbent. (5) The histamine release inhibitor comprises a component having 200-1,000 molecular weight in the methanol-eluted fraction. (6) The method for producing the histamine release inhibitor comprises making the histamine release inhibitor into dry powder and mixing the dry powder with another food powder. COPYRIGHT: (C)2004,JPO

    Prophylactic or therapeutic agent for disease based on cerebrovascular disorder and health food for preventing or treating disease based on cerebrovascular disorder
    9.
    发明专利
    Prophylactic or therapeutic agent for disease based on cerebrovascular disorder and health food for preventing or treating disease based on cerebrovascular disorder 有权
    基于脑血管病的疾病预防或治疗药物和基于脑血管病的预防或治疗疾病的健康食品

    公开(公告)号：JP2009051789A

    公开(公告)日：2009-03-12

    申请号：JP2007221943

    申请日：2007-08-29

    申请人： Kiichi Kawamata ,  Tomoyuki Nakamura ,  Yoshikazu Okada ,  Nozomi Sato ,  友幸 中村 ,  望 佐藤 ,  芳和 岡田 ,  貴一 川俣

    发明人： KAWAMATA KIICHI ,  OKADA YOSHIKAZU ,  SATO NOZOMI ,  NAKAMURA TOMOYUKI

    IPC分类号： A61K36/07 ,  A23L1/30 ,  A61P9/00 ,  A61P9/10

    摘要： PROBLEM TO BE SOLVED: To provide a new prophylactic or therapeutic agent having effects on diseases based on cerebrovascular disorder and a health food for prevention or treatment. SOLUTION: (1) The prophylactic or therapeutic agent for diseases based on cerebrovascular disorder comprises a liquid culture solution (derived component) of mycelium of Phellinus Linteus as an active ingredient. (2) The cerebrovascular disorder is cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage or cerebral edema in the prophylactic or therapeutic agent described in (1). (3) The health food for preventing or treating diseases based on cerebrovascular disorder comprises a liquid culture solution (derived component) of a mycelium of Phellinus Linteus as an active ingredient. (4) The disease based on cerebrovascular disorder is cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage or cerebral edema, in the health food for preventing or treating diseases based on cerebrovascular disorder described in (3). COPYRIGHT: (C)2009,JPO&INPIT

    摘要翻译： 要解决的问题：提供一种对脑血管障碍的疾病具有影响的新型预防或治疗剂和用于预防或治疗的保健食品。 解决方案：（1）基于脑血管障碍的疾病的预防或治疗剂包括作为活性成分的桑黄菌丝体的液体培养液（衍生成分）。 （2）脑血管障碍是（1）所述的预防或治疗剂中的脑梗塞，脑出血，蛛网膜下腔出血或脑水肿。 （3）用于预防或治疗基于脑血管障碍的疾病的保健食品包含作为活性成分的作为活性成分的桑黄的菌丝体的液体培养液（衍生成分）。 （4）根据（3）所述的基于脑血管障碍的预防或治疗疾病的保健食品，脑血管障碍的疾病是脑梗塞，脑出血，蛛网膜下腔出血或脑水肿。 版权所有（C）2009，JPO＆INPIT