Hydrophilic metal oxide nanoparticle having uniform particle size and method for producing the same
    4.
    发明专利
    Hydrophilic metal oxide nanoparticle having uniform particle size and method for producing the same 有权
    具有均匀颗粒尺寸的亲水性金属氧化物纳米颗粒及其生产方法

    公开(公告)号:JP2006104051A

    公开(公告)日:2006-04-20

    申请号:JP2005266657

    申请日:2005-09-14

    IPC分类号: C01G49/02 B01J19/00

    摘要: PROBLEM TO BE SOLVED: To provide a hydrophilic iron oxide nanoparticle having a uniform particle size by synthesizing paramagnetic iron oxide powder having a spherical particle of ≤20 nm having in an organic solvent thereby securing the uniformity of the particle, and converting the particle into the hydrophilic one by chemical surface modification. SOLUTION: The metal oxide nanoparticle contains: a nanoparticle composed of a metal oxide core and a shell composed of the element same as the metal component in the core and formed on the surface of the core; and an organic matter containing an element to be covalently bonded with the metal element in the shell and a hydrophilic functional group-containing organic substance. COPYRIGHT: (C)2006,JPO&NCIPI

    摘要翻译: 要解决的问题:通过合成具有在有机溶剂中的具有≤20nm的球形颗粒的顺磁性氧化铁粉末来提供具有均匀粒度的亲水性氧化铁纳米颗粒,从而确保颗粒的均匀性,并将 颗粒通过化学表面改性成亲水的。 解决方案:金属氧化物纳米颗粒包含:由金属氧化物核心构成的纳米颗粒和由与核心中的金属组分相同的元素组成的壳体,并形成在芯体的表面上; 以及含有与壳中的金属元素共价键合的元素和含有亲水性官能团的有机物质的有机物质。 版权所有(C)2006,JPO&NCIPI

    Inorganic nanoparticle onto which drug is fixed
    7.
    发明专利
    Inorganic nanoparticle onto which drug is fixed 审中-公开
    无机氮化合物固定在其上

    公开(公告)号:JP2007269632A

    公开(公告)日:2007-10-18

    申请号:JP2006093451

    申请日:2006-03-30

    摘要: PROBLEM TO BE SOLVED: To provide a composite of a medicinal compound (i. e. an active substance) and an inorganic nanoparticle, and a versatile, simple manufacturing method of the inorganic nanoparticle composite.
    SOLUTION: The inorganic nanoparticle composite has the active substance fixed through physical adsorption onto the surface of the inorganic particle with an average particle size of 1-500 nm. The inorganic nanoparticle composite is manufactured by mixing a solution of the medicinal compound with a dispersion of the inorganic nanoparticle and exposing the mixture to an ultrasonic irradiation. The inorganic nanoparticle composite is used in the field of life science or medical diagnosis.
    COPYRIGHT: (C)2008,JPO&INPIT

    摘要翻译: 待解决的问题:提供药物化合物(即活性物质)和无机纳米颗粒的复合物,以及无机纳米粒子复合材料的通用简单的制造方法。 解决方案:无机纳米颗粒复合材料通过物理吸附将活性物质固定在无机颗粒表面上,平均粒度为1-500nm。 通过将药物化合物的溶液与无机纳米颗粒的分散体混合并将混合物暴露于超声波照射来制造无机纳米颗粒复合物。 无机纳米颗粒复合材料用于生命科学或医学诊断领域。 版权所有(C)2008,JPO&INPIT