Method for producing nitrogen-containing fused heterocyclic compound
    7.
    发明专利
    Method for producing nitrogen-containing fused heterocyclic compound 审中-公开
    生产含氮混合杂环化合物的方法

    公开(公告)号:JP2011148751A

    公开(公告)日:2011-08-04

    申请号:JP2010012926

    申请日:2010-01-25

    CPC classification number: C07D471/02 C07D471/12

    Abstract: PROBLEM TO BE SOLVED: To provide a nitrogen-containing fused heterocyclic compound obtainable at a low catalyst amount and in a high yield even in the case of using a bromide as a raw material. SOLUTION: This method for producing the nitrogen-containing fused heterocyclic compound is provided by reacting a nitrogen-containing fused heterocyclic compound having a secondary nitrogen atom with a bromine compound having an oxygen-containing heterocyclic residue or a nitrogen-containing heterocyclic residue in the presence of copper or copper ion with a ligand, and performing dehydrobromination for bonding the corresponding nitrogen-containing fused heterocyclic compound with the compound having the oxygen-containing heterocyclic residue or the nitrogen-containing heterocyclic residue. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 待解决的问题:提供即使在使用溴化物作为原料的情况下,也可以低催化剂量和高收率得到的含氮稠合杂环化合物。 解决方案:这种制备含氮稠合杂环化合物的方法是通过使具有仲氮原子的含氮稠合杂环化合物与具有含氧杂环残基或含氮杂环残基的溴化合物 在铜或铜离子与配体的存在下进行脱氢溴化,使相应的含氮稠合杂环化合物与具有含氧杂环残基或含氮杂环残基的化合物结合。 版权所有(C)2011,JPO&INPIT

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