Electrochemical affinity biosensor system and method
    7.
    发明专利
    Electrochemical affinity biosensor system and method 审中-公开
    电化学生物传感器系统及方法

    公开(公告)号:JP2010229135A

    公开(公告)日:2010-10-14

    申请号:JP2010105307

    申请日:2010-04-30

    摘要: PROBLEM TO BE SOLVED: To provide a new osmium-based electrochemical species for detecting a wide variety of analytes using immunological techniques using an electrochemical oxidation/reduction label (also called an electron transfer agent or an electrochemical mediator label). SOLUTION: The new osmium-based electrochemical species usable in an immunoassay is provided. The osmium species can bond with a specific binding ligand for detecting related analytes and further can contain 1, 2 or 4 osmium centers that bond with the specific binding ligand using various bonding groups. Test sensors and diagnostic kits supporting electrode structures that can be used with the osmium-based electrochemical species are also provided. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal desired to analyze analytes that may be present at low concentration. COPYRIGHT: (C)2011,JPO&INPIT

    摘要翻译: 要解决的问题:提供一种新的基于锇的电化学物种,用于使用电化学氧化/还原标记(也称为电子转移剂或电化学介体标记)的免疫学技术检测各种各样的分析物。 解决方案:提供了可用于免疫测定的新的基于锇的电化学物质。 锇物质可与用于检测相关分析物的特异性结合配体结合,并且还可以含有使用各种键合基团与特异性结合配体键合的1,2或4个锇中心。 还提供了可用于锇基电化学物种的测试传感器和支持电极结构的诊断套件。 测试传感器可以被制造成支持已经被设计为提供期望分析可能以低浓度存在的分析物的电信号的放大的交叉指示的电极阵列。 版权所有(C)2011,JPO&INPIT