摘要:
Various embodiments of systems and methods for reporting and managing incidents are described herein. In one aspect, the method includes identifying a user logged into an incident reporting and alerting portal. A category for the logged-in user is identified. The category includes one of a reporter, a volunteer, and a responder. An incident report is received from the reporter. It is determined whether a comment is received on the incident report from the responder. When the comment is received, the comment is notified to the reporter. It is determined whether a reply to the comment is received from the reporter. When the reply to the comment is received, the reply is notified to the responder who commented on the incident report.
摘要:
An auxiliary drive for a trailer comprises a carrier that can be moved in relation to a chassis, said carrier holding a drive motor which can be used to drive a wheel of the trailer. The carrier can be swiveled from a drive position to a rest position and vice versa by means of an actuation lever. The moving mechanism provided for transmitting the movement of the manual actuation element comprises an energy storage or a servo-drive in order to prevent the operator from having to exert high operating forces.
摘要:
Various embodiments of systems and methods for adapting a reference workflow, according to changing data-contexts, during execution are described herein. The method involves detecting an entry to an adaptive segment in the reference workflow and invoking data context variables associated with the adaptive segment. Further the method includes invoking a set of ordered adaptation rules comprising a set of constraints on the data context variables. In an aspect, the method includes evaluating the rule-set using the one or more data context variables associated with the workflow. Based on the evaluation, a list of adaptation patterns is generated and provided as input to a pattern selector. In another aspect, adaptation patterns from the list of adaptation patterns are recursively called by the pattern selector. The called adaptation patterns are then executed as sub-processes within the adaptive segment.
摘要:
The invention relates to peptides with biological activity against infection having the amino acid sequence Z1-LE-X1-IP-X2-X3-X4-P-X5-X6-X7-X8-X9-X10-K-X11-X12-X13-X14-X15-Z2, wherein X1 is a lysine, alanine, or aspartic acid; X2 is a cysteine, methionine or isoleucine; X3 is a serine, cysteine, lysine or glycine; X4 is an isoleucine, alanine, phenylalanine or cysteine; X5 is a proline, D-proline or a substituted L- or D-proline; X6 is a cysteine or glutamic acid; X7 is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X8 is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X9 is an amino acid with an aromatic side chain; X10 is a glycine, alanine or asparagine; X11 is a proline, aspartic acid, octahydroindolyl-2-carboxylic acid or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; X12 is a phenylalanine, alanine, glycine, glutamic acid or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; X13 is an amino acid with a hydrophobic or an aromatic side chain; X14 is an amino acid with a hydrophobic or an aromatic side chain; X15 is a phenylalanine or deletion; Z1 is NH2 or a sequence of 1 to 10 amino acid residues; Z2 is COOH or a sequence of 1 to 10 amino acid residues; and peptides which are fragments and/or covalently linked oligomers and/or derivatives, especially amidated, alkylated, acylated, sulfated, pegylated, phosphorylated and/or glycosylated derivatives, and mutants thereof, and with the provisio that (a) if X12 is alanine, glycine, glutamic acid, or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid than X13, X14 and X15 are phenylalanine, valine and phenylalanine respectively; and/or (b) if X12 is phenylalanine, than X13, X14 and X15 are valine, phenylalanine and a deletion, respectively; and (c) that there are at maximum two cysteine residues in a peptide.
摘要:
The invention relates to oligomeric peptides with biological activity against HIV infection having the amino acid sequence (Z1-LE-X1-IP—X2—X3—X4—P—X5—X6—X7—X8—X9—X10—K—X11—X12—X13—X14—X15-Z2)n, wherein n indicates the number of monomeric peptide chains, whereby n is 2, 3 or 4; X1 is a lysine, alanine, or aspartic acid; X2 is a cysteine, methionine or isoleucine; X3 is a serine, cysteine, lysine or glycine; X4 is an isoleucine, alanine, phenylalanine or cysteine; X5 is a proline, D-proline or a substituted L- or D-proline; X6 is a cysteine or glutamic acid; X7 is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X8 is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X9 is an amino acid with an aromatic side chain; X10 is a glycine, alanine or asparagine; X11 is a proline, aspartic acid, octahydroindolyl-2-carboxylic acid or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; X12 is a phenylalanine, alanine, glycine, glutamic acid or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; X13 is an amino acid with a hydrophobic or an aromatic side chain; X14 is an amino acid with a hydrophobic or an aromatic side chain; X15 is a phenylalanine or deletion; Z1 is NH2 or a sequence of 1 to 10 amino acid residues; Z2 is COOH or a sequence of 1 to 10 amino acid residues; and oligomeric peptides which are fragments thereof and/or derivatives, especially amidated, alkylated, acylated, sulfated, pegylated, phosphorylated and/or glycosylated derivatives, and mutants thereof; and with the proviso that (a) if X12 is alanine, glycine, glutamic acid, or D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid than X13, X14 and X15 are phenylalanine, valine and phenylalanine respectively; and/or (b) if X12 is phenylalanine, than X13, X14 and X15 are valine, phenylalanine and a deletion, respectively; and (c) there are at maximum three cysteine residues in a peptide; and (d) the oligomeric peptide has not the sequence (LEAIPCSIPPEFLFGKPFVF)2 (VIR-576); and (e) the monomeric peptide chains are not linked by peptide bonds between the N-terminus of one peptide chain to the C-terminus of another peptide chain.
摘要:
Example systems and methods of recommending an item are presented. In one example, preference values for items by multiple users, as well as property values for multiple properties of the items by the users, are accessed. Reference property values for the properties of the items are generated based on the property values. Average deviations from the reference property values for the properties across a first group of the items by a target user are generated. Expected property values for the properties of a second group of the items for the target user are generated based on the reference property values and the average deviations. Preference values of the target user for the second group of the items are estimated based on the expected property values. At least one of the second group of the items is recommended to the target user based on the estimated preference values.
摘要:
A system for non-linearly editing video and audio information, uses a device for recognizing speech in the audio information and for generating a character sequence, particularly an ASCII character sequence, to produce an edit decision list (EDL). The generated character sequence is displayed on the display screen of an indicator. With reference to marked parts of the character sequence displayed on the display screen of the indicator, editing data is derived for the EDL.
摘要:
A distorted signal available at the output of a preamplifier which are derived from a magnetically recorded digital signal is differentiated twice. The second derivative signal obtained by that double differentiation is used to derive one set of pulses corresponding to both positive and negative peaks of the twice differented signal, which are then used to clock a D-flipflop. Another set of pulses is derived from the double differentiated signal responding to peaks of only one polarity thereof and these are applied to the D input of the flipflop. The output of the flipflop is a reconstituted replica of the digital signal that was originally recorded.
摘要:
To effectively eliminate cross-talk between the weak signals picked up by a tape transducer pick-up head with signals being applied to a recording head, a disk-like headwheel carrier has a disk-like headwheel secured thereto. The disk-like headwheel carrier is formed with a recess which defines a chamber (6) in which the preamplifier for the reproduced signals is placed. Transducer leads are passsed in a channel duct formed between the headwheel carrier and the disk-like headwheel, which is in plate form. Preferably, both the disk-like headwheel as well as the carrier are made of lightweight metal, such as aluminum, so that the reproducing amplifier is totally shielded. The recording amplifier can be placed on top of the disk-like headwheel, separated and shielded from the reproducing preamplifier.
摘要:
Various embodiments of systems and methods for reporting and managing incidents are described herein. In one aspect, the method includes identifying a user logged into an incident reporting and alerting portal. A category for the logged-in user is identified. The category includes one of a reporter, a volunteer, and a responder. An incident report is received from the reporter. It is determined whether a comment is received on the incident report from the responder. When the comment is received, the comment is notified to the reporter. It is determined whether a reply to the comment is received from the reporter. When the reply to the comment is received, the reply is notified to the responder who commented on the incident report.