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公开(公告)号：US20120303089A1
公开(公告)日：2012-11-29
申请号：US13575965
申请日：2011-02-02
IPC分类号： A61N1/36
CPC分类号： A61N1/0534 , A61N1/36082 , A61N1/36185
摘要： A method and control system for determining and applying stimulation settings for a brain stimulation probe (10, 12) is provided. The brain stimulation probe (10, 12) comprises a plurality of stimulation electrodes (11). The method comprises for multiple stimulation electrodes (11) of the plurality of stimulation electrodes (11): applying a test current and determining a corresponding patient response, determining a volume of influence based (32, 52, 71, 91) on the test current and a position of the stimulation electrode (11), combining the volume of influence (32, 52, 71, 91) and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence (32, 52, 71, 91) to an anatomic structure (33, 43, 53), and determining an intersection (41, 51) of the volume of influence (32, 52, 71, 91) and the associated anatomic structure (33, 43, 53). Then, based on the determined intersections (41, 51) an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe (10, 12) are determined.
摘要翻译： 提供了一种用于确定和应用脑刺激探针（10,12）的刺激设置的方法和控制系统。 脑刺激探针（10,12）包括多个刺激电极（11）。 该方法包括多个刺激电极（11）的多个刺激电极（11）：施加测试电流并确定相应的患者反应，确定基于（32,52,71,91）的测试电流的影响体积 以及刺激电极（11）的位置，将影响体积（32,52,71,91）和相应的患者反应与刺激诱导行为的广义解剖学知识相结合，影响体积（32,52,71） ，91）到解剖结构（33,43,53），并且确定影响体积（32,52,71,91）和相关联的解剖结构（33,43,53）的交叉点（41,51） 。 然后，基于确定的交叉点（41,51），确定用于脑刺激探针（10,12）的最佳刺激体积和相应的刺激设置。
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2.发明申请System and A Method for Determination of an Orientation of a Biomedical Stimulation Device 审中-公开系统和一种确定生物医学刺激装置取向的方法公开(公告)号：US20120303088A1
公开(公告)日：2012-11-29
申请号：US13574719
申请日：2011-01-19
申请人： Patrick Wilhelmus Van Kaam , Johan Gerard Kleibeuker , Hubert Cécile François Martens , Emil-Codrut Toader
发明人： Patrick Wilhelmus Van Kaam , Johan Gerard Kleibeuker , Hubert Cécile François Martens , Emil-Codrut Toader
IPC分类号： A61N1/36
CPC分类号： A61B5/062 , A61N1/0534 , A61N1/36135 , A61N1/36182
摘要： The application relates to a system (1) for determination of an orientation (14) of a biomedical stimulation device (2) in respect to an object (20). The system comprises the first biomedical stimulation device (2) comprising at least two stimulator for elements (4A;4C) and a generator (22) arranged for feeding the stimulator elements (4A;4C) with time-varying electric signals (6A;6C), wherein the time-varying electric signals (6A;6C) differ by a predetermined phase. The system further comprises a sensor device (10) with a known relative position (X;α) with respect to the first biomedical stimulation device (2), arranged for sensing a sensing signal (8) from the stimulator elements (4A;4C), wherein the sensing signal (8) is originated from the time-varying electric signals (6A;6C) from the stimulator elements (4A;4C) and a processor device (12) arranged for determining the orientation (14) of the first biomedical stimulation device (2) based on a sensed phase of the sensing signal (8), phases of the time-varying signals (6A;6C) and the known relative position (X;α). Said system accurately determines the orientation, i.e. angular position, of the biomedical stimulation device in respect to the object. The orientation is also accurately determined when the biomedical stimulation device is implanted in the object. Such a system is relatively cheap. The application also relates to a method for determination of an orientation (14) of a first biomedical stimulation device (2) in respect to an object (20).
摘要翻译： 本申请涉及一种用于确定生物医学刺激装置（2）相对于物体（20）的取向（14）的系统（1）。 该系统包括第一生物医学刺激装置（2），其包括用于元件（4A; 4C）的至少两个刺激器和布置成用于将刺激元件（4A; 4C）馈送到时变电信号（6A; 6C）的发生器 ），其中所述时变电信号（6A; 6C）相差预定相位。 所述系统还包括相对于所述第一生物医学刺激装置（2）具有已知相对位置（X;α）的传感器装置（10），所述相对位置被设置用于从所述刺激器元件（4A; 4C）感测感测信号（8） ，其中所述感测信号（8）源自所述刺激器元件（4A; 4C）的时变电信号（6A; 6C）和布置成用于确定所述第一生物医学的方向（14）的处理器装置（12） 基于感测信号（8）的感测相位，时变信号（6A; 6C）的相位和已知的相对位置（X;α）的刺激装置（2）。 所述系统精确地确定生物医学刺激装置相对于物体的取向，即角位置。 当将生物医学刺激装置植入物体时也准确地确定取向。 这样的系统相对便宜。 本申请还涉及用于确定第一生物医学刺激装置（2）相对于物体（20）的取向（14）的方法。
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公开(公告)号：US20120277821A1
公开(公告)日：2012-11-01
申请号：US13517473
申请日：2010-12-21
IPC分类号： A61N1/36
CPC分类号： A61N1/0534 , A61N1/36082 , A61N1/36182 , A61N1/36185
摘要： System for providing a stimulus comprising a probe with multiple electrodes each capable of providing a particular current to surrounding tissue a generator for providing to each of the electrodes the particular current a controller for controlling the generator to provide current to the electrodes to achieve a desired electrical field around the probe.
摘要翻译： 用于提供刺激的系统，其包括具有多个电极的探针，每个电极能够向周围组织提供特定的电流，用于向每个电极提供特定电流，用于控制发电机以向电极提供电流以实现期望的电 探头周围的场。
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公开(公告)号：US20120109262A1
公开(公告)日：2012-05-03
申请号：US13285084
申请日：2011-10-31
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/0531 , A61N1/0553 , A61N1/36146 , A61N1/36157 , A61N1/36182 , A61N1/36185
摘要： A neurostimulation device is provided comprising an input, a neurostimulation probe, a stimulation unit and a distribution calculation module. At the input stimulation data is received comprising information relating to a stimulation preferability and an orientation of at least one fiber bundle. The neurostimulation probe comprises an array of stimulation electrodes which are coupled to the stimulation unit. The stimulation unit, in accordance with a specified current distribution, provides currents to the respective stimulation electrodes for generating an electric field gradient. The distribution calculation module is coupled to the input and the stimulation unit for based on the stimulation data determining a preferred position and orientation for the electric field gradient, and based on the preferred position and orientation for the electric field gradient, calculating the specified current distribution.
摘要翻译： 提供神经刺激装置，其包括输入，神经刺激探针，刺激单元和分布计算模块。 在输入刺激数据被接收包括与刺激优选性和至少一个纤维束的取向有关的信息。 神经刺激探针包括耦合到刺激单元的刺激电极的阵列。 刺激单元根据指定的电流分布，向相应的刺激电极提供电流以产生电场梯度。 分布计算模块基于确定电场梯度的优选位置和取向的刺激数据耦合到输入和刺激单元，并且基于电场梯度的优选位置和取向，计算指定的电流分布 。
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公开(公告)号：US07602694B2
公开(公告)日：2009-10-13
申请号：US10538332
申请日：2003-11-26
IPC分类号： G11B7/00
CPC分类号： G11B7/242 , G11B7/24038 , G11B7/244 , G11B7/2467 , G11B7/2534 , G11B7/2578 , G11B7/259
摘要： A dual-stack recordable optical data storage medium wherein a focused radiation beam having a wavelength λ enters through an entrance face of the medium during recording. The medium includes a substrate, a first recording stack L0, including a recording layer, the first recording stack L0 having an optical reflection value RL0 and an optical absorption value AL0 at the wavelength λ, and a second recording stack L1 including a recording layer, the second recording stack L1 having an optical reflection value RL1 and an optical absorption value AL1 at the wavelength λ, and a transparent spacer layer between the recording stacks. The second stack is closer to the entrance face than the first stack. By fulfilling the formula AL1≦1−Rmin−√(Rmin/RL0), where Rmin is the minimum effective optical reflection value for each recording stack, full compatibility is achieved with a read only version of the medium.
摘要翻译： 其中具有波长λ的聚焦辐射束在记录期间通过介质的入射面入射的双层可记录光学数据存储介质。 介质包括基板，包括记录层的第一记录堆叠L0，具有光反射值RL0的第一记录堆叠L0和波长λ处的光吸收值AL0以及包括记录层的第二记录堆叠L1， 具有光反射值RL1和波长λ处的光吸收值AL1的第二记录叠层L1和记录层之间的透明间隔层。 第二堆叠比第一堆叠更靠近入口面。 通过满足公式AL1 <= 1-Rmin-√（Rmin / RL0），其中Rmin是每个记录堆叠的最小有效光学反射值，使用仅读介质实现完全兼容性。
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公开(公告)号：US07573802B2
公开(公告)日：2009-08-11
申请号：US10501429
申请日：2003-01-16
IPC分类号： G11B7/24
CPC分类号： G11B7/007 , G11B7/0938 , G11B7/24
摘要： A dual-stack optical data storage medium for write-once recording using a focused radiation beam entering through an entrance face of the medium is described. The medium includes at least one substrate with present on a side thereof a first recording stack L0 having a write-once type L0 recording layer with an absorption kL0 and a second recording stack L1 including a write-once type L1 recording layer with an absorption kL1. The first recording stack L0 has an optical reflection value RL0 and an optical transmission value TL0 and the second recording stack has an optical reflection value RL1. The first recording stack is present at a position closer to the entrance face than the second recording stacks When the following conditions are fulfilled: 0.45 ≦TL0≦0.75 and 0.40 ≦RL1≦0.80 and kL0
摘要翻译： 描述了使用从介质的入射面入射的聚焦辐射束进行一次写入记录的双层光学数据存储介质。 介质包括至少一个衬底，其一侧上具有第一记录堆叠L0，其具有具有吸收kL0的一次写入型L0记录层和包括具有吸收kL1的一次写入型L1记录层的第二记录堆叠L1 。 第一记录堆L0具有光反射值RL0和光传输值TL0，第二记录堆具有光反射值RL1。 第一记录堆叠存在于比第二记录堆叠更接近入射面的位置当满足以下条件时：0.45 <= TL0 <= 0.75和0.40 <= RL1 <= 0.80和kL0 <0.3并且kL1 <0.3a 实现了可以在标准DVD-ROM播放器中播放的双栈一次性介质。
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7.发明授权公开(公告)号：US09248301B2
公开(公告)日：2016-02-02
申请号：US13054857
申请日：2009-07-22
CPC分类号： A61N1/37288 , A61N1/362 , A61N1/37252
摘要： A system for communicating information between at least two medical devices implanted within the body of a subject using volume conduction of electrical signals as a means of communication and wherein one of the implanted medical devices is configured to provide electrical stimulation to the tissue is disclosed. The system comprises a first implant device having at least two transmit electrodes configured to transmit electrical stimulation pulses, wherein one of the electrodes may be a common return electrode, an encoding means configured to employ a channel as a transmitter transmission medium for stimulation pulses and encoding the information into the stimulation pulses, a second implant device having at least two receive electrodes configured to receive the transmitted stimulation pulses with encoded information, and a decoding means configured to decode the information encoded into the stimulation pulses. The disclosed system provides reliable and efficient communication between implantable devices.
摘要翻译： 公开了一种系统，用于在作为通信手段的电信号的体积传导之间在植入物体内的至少两个医疗设备之间传送信息，并且其中植入的医疗设备中的一个被配置为向组织提供电刺激。 所述系统包括具有至少两个发射电极的第一注入装置，所述至少两个发射电极被配置为传输电刺激脉冲，其中所述电极中的一个可以是公共返回电极，编码装置被配置为使用通道作为用于刺激脉冲的发射器传输介质和编码 将信息输入到刺激脉冲中，具有至少两个接收电极的第二植入装置，所述接收电极被配置为用编码信息接收所发送的刺激脉冲;以及解码装置，被配置为对编码为刺激脉冲的信息进行解码。 所公开的系统在可植入装置之间提供可靠和有效的通信。
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公开(公告)号：US20110128841A1
公开(公告)日：2011-06-02
申请号：US13017234
申请日：2011-01-31
申请人： Ronald Joseph Antonius Van Den Oetelaar , Hubert Cécile François Martens , Wilhelmus Robert Koppers , Pierre Hermanus Woerlee
发明人： Ronald Joseph Antonius Van Den Oetelaar , Hubert Cécile François Martens , Wilhelmus Robert Koppers , Pierre Hermanus Woerlee
IPC分类号： G11B7/24
CPC分类号： G11B7/0045 , G11B7/00456 , G11B7/00736 , G11B7/24038 , G11B2007/0013
摘要： The present invention relates to a recording apparatus, record carrier and method of recording data on at least two layers of a recording medium by using a radiation power, wherein individual recording speeds are determined for respective ones of the at least two layers at different values of the radiation power. A recording speed to be used for recording on an individual one of the at least two recording layers is selected based on a maximum radiation power specified for the recording operation, and the speed of the recording operation is controlled individually for each of the at least two layers based on the selected recording speed. The determination of the individual recording speeds at different radiation power values may be written or embossed on the record carrier. Furthermore, a recording sequence used for recording on the recording layers can be set based on the sensitivities and thus recording speeds. Thereby, total recording time can be minimized for multi-layer recording media.
摘要翻译： 本发明涉及一种通过使用辐射功率在至少两层记录介质上记录数据的记录装置，记录载体和方法，其中针对所述至少两个层中的不同值确定各个记录速度 辐射功率。 基于为记录操作指定的最大辐射功率来选择用于记录在至少两个记录层中的单个记录层上的记录速度，并且对于至少两个记录层中的每一个单独地控制记录操作的速度 基于所选记录速度的层。 在不同辐射功率值下的单个记录速度的确定可以被写入或压印在记录载体上。 此外，可以基于灵敏度和因此记录速度来设置用于记录层上的记录的记录顺序。 因此，对于多层记录介质，总记录时间可以最小化。
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9.发明授权Apparatus and method for recording an information on a recordable optical record carrier using oval spot profile 失效使用椭圆形光斑轮廓在可记录光学记录载体上记录信息的装置和方法公开(公告)号：US07397734B2
公开(公告)日：2008-07-08
申请号：US10537065
申请日：2003-11-06
IPC分类号： G11B7/00
CPC分类号： B82Y10/00 , G11B7/1369 , G11B7/139 , G11B7/1398
摘要： A method and a corresponding apparatus for recording an information on a recordable optical record carrier (2) by irradiation of a light beam through an optical system (3-7) onto said record carrier (2) for forming marks and lands representing said information along an information recording direction (t), obtains a higher recording density, and thus higher data capacity, by using astigmatism for influencing the light beam from the light source (8) to the record carrier (2) during recording of information so as to obtain a light beam having a substantially oval spot profile having a shorter axis in the information recording direction (t), i.e., the tangential direction for an optical disc, compared to the direction (r) orthogonal thereto, i.e., the radial direction.
摘要翻译： 一种用于通过将光束通过光学系统（3-7）照射到所述记录载体（2）上来记录可记录光学记录载体（2）上的信息的方法和相应装置，用于形成表示所述信息的标记和平台 信息记录方向（t）通过在记录信息期间通过使用用于影响从光源（8）到记录载体（2）的光束的散光来获得更高的记录密度，从而获得更高的数据容量，从而获得 与沿其正交的方向（r）相比，具有在信息记录方向（t）上具有较短轴线的基本上椭圆形的光斑轮廓，即光盘的切线方向。
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公开(公告)号：US09412407B2
公开(公告)日：2016-08-09
申请号：US10557686
申请日：2004-05-17
IPC分类号： G11B7/24 , G03C5/00 , G11B7/24038 , G11B7/0045 , G11B7/24062 , G11B7/246 , G11B7/00
CPC分类号： G11B7/24038 , G11B7/00455 , G11B7/24 , G11B7/24062 , G11B7/246 , G11B2007/0013 , G11B2220/235 , G11B2220/2562
摘要： The invention relates to an optical storage medium comprising below an entrance face (EF) a higher recording stack (ST0) comprising a higher recording layer (L0) and at least a lower recording stack (ST1), said lower recording stack (ST1) being recorded or read back by a radiation beam (4) entering into the optical storage medium through the entrance face (EF) with a wavelength (λ), focused on said lower recording stack (ST1) and transmitted through the higher recording stack (ST0), a recording of the higher recording layer (L0) causing an optical thickness variation between recorded and unrecorded areas of said first recording layer (L0), which is included into the range [0.03λ, 0.125λ].
摘要翻译： 本发明涉及一种光学存储介质，其包括在入口面（EF）下方，包括较高记录层（L0）和至少下层记录堆叠（ST1）的较高记录堆叠（ST0），所述下记录堆叠（ST1） 通过聚焦在所述下记录叠层（ST1）上并通过较高记录叠层（ST0）传输的波长（λ）的入射面（EF）通过入射到光存储介质的辐射束（4）记录或读回， 记录在[0.03λ，0.125λ]范围内的所述第一记录层（L0）的记录区域和未记录区域之间的光学厚度变化的记录层（L0）。
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