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公开(公告)号:US20160312311A1
公开(公告)日:2016-10-27
申请号:US14772976
申请日:2014-02-24
申请人: Fallon LIN , Young Shin CHO , Julian Roy LEVELL , Margaret Elise MCLAUGHLIN , Ronald MEYER , Raymond PAGLIARINI , Veronica SAENZ-VASH , Olga SHEBANOVA , Huili ZHAI
发明人: Young Shin Cho , Julian Roy Levell , Fallon Lin , Margaret Elise McLaughlin , Ronald Meyer , Raymond Pagliarini , Veronica Saenz-Vash , Olga Shebanova , Huili Zhai
CPC分类号: C12Q1/6888 , C12Q1/6886 , C12Q2600/106 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158 , G01N33/6848 , G01N33/6875 , G01N2333/47 , G01N2333/904 , G01N2800/52 , G01N2800/7028
摘要: The invention provides methods of detecting cancer and detecting activity of IDH inhibitors, and methods of screening for IDH inhibitors by detecting levels of H3K9me2.
摘要翻译: 本发明提供了检测癌症和检测IDH抑制剂的活性的方法,以及通过检测H3K9me2的水平来筛选IDH抑制剂的方法。