公开(公告)号：US06896907B2

公开(公告)日：2005-05-24

申请号：US10135763

申请日：2002-05-01

申请人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

发明人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

IPC分类号： A61K35/22 ,  A61K45/06 ,  A61P31/00 ,  A61P35/00 ,  A61K35/24 ,  A61K35/23

CPC分类号： A61K45/06 ,  A61K35/22 ,  A61K2300/00

摘要： The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically acceptable additives selected from anticancer compounds, antibiotics, drugs, therapeutic and nutraceutic agents, ions and similar molecules which are targeted to the living systems.

摘要翻译： 本发明涉及一种新型药物组合物，其包含有效量的来自牛尿馏分的生物活性级分作为生物利用度促进剂和选自抗癌化合物，抗生素，药物，治疗和营养药物，离子和类似分子的药学上可接受的添加剂 到生活系统。

公开(公告)号：US06410059B1

公开(公告)日：2002-06-25

申请号：US09726307

申请日：2000-12-01

申请人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

发明人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

IPC分类号： A61K3522

CPC分类号： A61K45/06 ,  A61K35/22 ,  A61K2300/00

摘要： A pharmaceutical composition comprising an antibiotic and cow urine distillate in an amount effective to enhance antimicrobial effect of the antibiotic is disclosed. The antibiotic can be an antifungal agent. The antibiotic can be a quinolone or a fluoroquinolone. The antifungal agent can be azoles, clotrimazole, mystatin or amphotericin.

摘要翻译： 公开了一种药物组合物，其包含抗生素和牛尿液馏出物，其量有效提高抗生素的抗微生物作用。 抗生素可以是抗真菌剂。 抗生素可以是喹诺酮或氟喹诺酮类。 抗真菌剂可以是唑类，克霉唑，丝裂霉素或两性霉素。

公开(公告)号：US06514541B2

公开(公告)日：2003-02-04

申请号：US09536124

申请日：2000-03-28

申请人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

IPC分类号： A61K3578

CPC分类号： A61K36/23 ,  A61K36/534 ,  Y10S514/924 ,  A61K2300/00

摘要： A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant Trachyspermum ammi, mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of Mentha spicata and Mentha arvensis, and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

摘要翻译： 一种可用于治疗耐药性细菌感染的制剂，其包含从植物Trachyspermum ammi获得的有效量的百里酚，含有从Mentha spicata和Mentha arvensis的杂种获得的适量的单萜和常规添加剂的薄荷油。 通过施用治疗有效量的制剂，通过混合上述成分和用于治疗患者耐药性的方法来制备制剂的方法。

公开(公告)号：US20050100610A1

公开(公告)日：2005-05-12

申请号：US10822790

申请日：2004-04-13

申请人： Suman Khanuja ,  Sushil Kumar ,  Ajit Shasany ,  Jai Arya ,  Mahendra Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Gupta ,  Vivek Gupta ,  Madan Gupta ,  Ram Verma ,  Sweta Agarwal ,  Sunil Mansinghka ,  Suresh Dawle

发明人： Suman Khanuja ,  Sushil Kumar ,  Ajit Shasany ,  Jai Arya ,  Mahendra Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Gupta ,  Vivek Gupta ,  Madan Gupta ,  Ram Verma ,  Sweta Agarwal ,  Sunil Mansinghka ,  Suresh Dawle

IPC分类号： A61K35/22 ,  A61K45/06 ,  A61P31/00 ,  A61P35/00 ,  A61K33/40 ,  A61K31/4965 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/65

CPC分类号： A61K45/06 ,  A61K35/22 ,  A61K2300/00

摘要： The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically acceptable additives selected from anticancer compounds, antibiotics, drugs, therapeutic and nutraceutic agents, ions and similar molecules which are targeted to the living systems.

摘要翻译： 本发明涉及一种新型药物组合物，其包含有效量的来自牛尿馏分的生物活性级分作为生物利用度促进剂和选自抗癌化合物，抗生素，药物，治疗和营养药物，离子和类似分子的药学上可接受的添加剂 到生活系统。

公开(公告)号：US06824795B2

公开(公告)日：2004-11-30

申请号：US10322731

申请日：2002-12-19

申请人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

IPC分类号： A61K3578

CPC分类号： A61K36/23 ,  A61K36/534 ,  A61K2300/00

摘要： A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant Trachyspermum ammi, mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of Mentha spicata and Mentha arvensis, and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

摘要翻译： 一种可用于治疗耐药性细菌感染的制剂，其包含从植物Trachyspermum ammi获得的有效量的百里酚，含有从Mentha spicata和Mentha arvensis的杂种获得的适量的单萜和常规添加剂的薄荷油。 通过施用治疗有效量的制剂，通过混合上述成分和用于治疗患者耐药性的方法来制备制剂的方法。

公开(公告)号：US07235262B2

公开(公告)日：2007-06-26

申请号：US10822790

申请日：2004-04-13

申请人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

发明人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Ajit Kumar Shasany ,  Jai Shankar Arya ,  Mahendra Pandurang Darokar ,  Monika Singh ,  Prachi Sinha ,  Soumya Awasthi ,  Subhash Chandra Gupta ,  Vivek Kumar Gupta ,  Madan Mohan Gupta ,  Ram Kishore Verma ,  Sweta Agarwal ,  Sunil Balkrishna Mansinghka ,  Suresh Haribhau Dawle

IPC分类号： A61K35/22

CPC分类号： A61K45/06 ,  A61K35/22 ,  A61K2300/00

摘要： The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically acceptable additives selected from anticancer compounds, antibiotics, drugs, therapeutic and nutraceutic agents, ions and similar molecules which are targeted to the living systems.

摘要翻译： 本发明涉及一种新型药物组合物，其包含有效量的来自牛尿馏分的生物活性级分作为生物利用度促进剂和选自抗癌化合物，抗生素，药物，治疗和营养药物，离子和类似分子的药学上可接受的添加剂 到生活系统。