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1.发明申请公开(公告)号：US20080255557A1
公开(公告)日：2008-10-16
申请号：US12102477
申请日：2008-04-14
CPC分类号： A61L17/10 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00004 , A61B2017/00893 , A61B2017/0414 , A61B2017/0458 , A61B2017/06171 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/105 , A61L17/145 , A61L2300/402 , A61L2300/406 , A61L2300/41 , D04C1/12 , D10B2509/04
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
摘要翻译： 一种具有最小不吸收质量的新型高抗拉强度半吸收复合缝合线。 缝线具有由生物可吸收聚合物制成的芯。 芯由编织护套覆盖。 编织护套由可吸收纱线和生物可吸收纱线制成。 生物可吸收纱线由生物可吸收聚合物的至少一根丝制成。 非吸收性纱线由至少一根超高分子量聚乙烯丝制成。
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公开(公告)号：US07329271B2
公开(公告)日：2008-02-12
申请号：US10740024
申请日：2003-12-18
CPC分类号： D04C1/12 , A61B17/06166 , A61B2017/00004 , A61B2017/06185 , A61L17/04 , A61L17/105 , A61L17/12 , A61L17/145 , D07B1/025 , D07B2201/1036 , D07B2201/1096 , D07B2205/2014 , D10B2509/04 , D07B2801/10
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
摘要翻译： 一种具有最小不吸收质量的新型高抗拉强度半吸收复合缝合线。 缝线具有由生物可吸收聚合物制成的芯。 芯由编织护套覆盖。 编织护套由可吸收纱线和生物可吸收纱线制成。 生物可吸收纱线由生物可吸收聚合物的至少一根丝制成。 非吸收性纱线由至少一根超高分子量聚乙烯丝制成。
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3.发明申请公开(公告)号：US20120323273A1
公开(公告)日：2012-12-20
申请号：US13330741
申请日：2011-12-20
IPC分类号： A61L17/10
CPC分类号： A61L17/10 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00004 , A61B2017/00893 , A61B2017/0414 , A61B2017/0458 , A61B2017/06171 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/105 , A61L17/145 , A61L2300/402 , A61L2300/406 , A61L2300/41 , D04C1/12 , D10B2509/04
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
摘要翻译： 一种具有最小不吸收质量的新型高抗拉强度半吸收复合缝合线。 缝线具有由生物可吸收聚合物制成的芯。 芯由编织护套覆盖。 编织护套由可吸收纱线和生物可吸收纱线制成。 生物可吸收纱线由生物可吸收聚合物的至少一根丝制成。 非吸收性纱线由至少一根超高分子量聚乙烯丝制成。
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公开(公告)号：US4720384A
公开(公告)日：1988-01-19
申请号：US898653
申请日：1986-08-21
申请人： Robert C. Di Luccio , Ray B. Duggins , Eli Shefter
发明人： Robert C. Di Luccio , Ray B. Duggins , Eli Shefter
CPC分类号： A61K9/0092
摘要： Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.
摘要翻译： 提供了含有中空细管药物递送系统的药物组合物。 组合物包含药学上合适的载体，优选以胶囊，片剂，悬浮液或栓剂的形式，以及至少一种药物递送系统，其基本上由（1）具有膜外护套和中空芯的聚合物管组成， 和（2）包含在核心内的至少一种药物化合物，所述系统包含在组合物中，其量足以在预定时间内以预定的速率输送治疗量的药物。 通过改变聚合物，外鞘的渗透性，药物，管的中空芯中的药物浓度，管直径，管长度，管芯直径和管末端的密封，种类繁多 的药物治疗量，速率和给药时间可以实现。
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公开(公告)号：US08109967B2
公开(公告)日：2012-02-07
申请号：US12102477
申请日：2008-04-14
IPC分类号： A61B17/04
CPC分类号： A61L17/10 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00004 , A61B2017/00893 , A61B2017/0414 , A61B2017/0458 , A61B2017/06171 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/105 , A61L17/145 , A61L2300/402 , A61L2300/406 , A61L2300/41 , D04C1/12 , D10B2509/04
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
摘要翻译： 一种具有最小不吸收质量的新型高抗拉强度半吸收复合缝合线。 缝线具有由生物可吸收聚合物制成的芯。 芯由编织护套覆盖。 编织护套由可吸收纱线和生物可吸收纱线制成。 生物可吸收纱线由生物可吸收聚合物的至少一根丝制成。 非吸收性纱线由至少一根超高分子量聚乙烯丝制成。
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6.发明授权Use of vinyl alcohol homopolymer and copolymers for tableting active materials 失效乙烯醇均聚物和共聚物用于压片活性物质的应用
公开(公告)号：US4990335A
公开(公告)日：1991-02-05
申请号：US165230
申请日：1988-05-12
申请人： Linda R. Bateman , Robert C. Di Luccio , Clare A. Stewart, Jr. , Donna L. Visioli , David P. Beach-Coffin
发明人： Linda R. Bateman , Robert C. Di Luccio , Clare A. Stewart, Jr. , Donna L. Visioli , David P. Beach-Coffin
CPC分类号： C11D17/0073 , A61K9/2027
摘要： Method of making tablets for active ingredient delivery by compressing a mixture of active ingredient and granular, high viscosity, fully hydrolyzed polyvinyl alcohol or copolymer of vinyl alcohol with methyl acrylate or methyl methacrylate. By use of a crystalline, heat treated polymer, a tablet providing quick active ingredient release is obtained. By using an amorphous, non-heat treated polymer a tablet providing prolonged active ingredient release is obtained. By using blends of crystalline and amorphous polymers, tablets having a range of active ingredient release characteristics can be obtained. The granular, high viscosity, fully hydrolyzed polymers provide flowability, compressibility and processing versatility advantages over conventional tablet binders.
摘要翻译： 通过压缩活性成分和颗粒状，高粘度，完全水解的聚乙烯醇或乙烯醇与丙烯酸甲酯或甲基丙烯酸甲酯的共聚物的混合物制备用于活性成分递送的片剂的方法。 通过使用结晶的经热处理的聚合物，获得了提供快速活性成分释放的片剂。 通过使用无定形的未加热处理的聚合物，获得延长的活性成分释放的片剂。 通过使用结晶和无定形聚合物的混合物，可以获得具有一定范围的活性成分释放特性的片剂。 颗粒状，高粘度，完全水解的聚合物提供了流畅性，压缩性和加工多功能性优于传统的片剂粘合剂。
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公开(公告)号：US4524099A
公开(公告)日：1985-06-18
申请号：US526960
申请日：1983-08-30
申请人： Robert C. Di Luccio
发明人： Robert C. Di Luccio
CPC分类号： B32B27/32 , Y10S428/906 , Y10S428/913 , Y10T428/2495 , Y10T428/31757 , Y10T428/31913 , Y10T428/31928
摘要： A transparent, elastomeric, composite film structure having a core ethylene/vinyl acetate copolymer and outer layers of a low density ethylene homopolymer or copolymer with a small amount of another .alpha.-olefin or vinyl acetate is made by coextrusion of the polymers in a three-layer combining adapter and quenching on a chill roll. This film structure is useful as a wrapping material, especially for heat-sensitive articles.
摘要翻译： 具有核心乙烯/乙酸乙烯酯共聚物和低密度乙烯均聚物或少量另外的α-烯烃或乙酸乙烯酯的共聚物的透明的，弹性体的复合膜结构是通过三元共聚物共挤出而制成的， 层组合适配器和淬火辊上的淬火。 该膜结构可用作包裹材料，特别是对于热敏性物品。
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公开(公告)号：US07357810B2
公开(公告)日：2008-04-15
申请号：US10740023
申请日：2003-12-18
CPC分类号： A61L17/10 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00004 , A61B2017/00893 , A61B2017/0414 , A61B2017/0458 , A61B2017/06171 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/105 , A61L17/145 , A61L2300/402 , A61L2300/406 , A61L2300/41 , D04C1/12 , D10B2509/04
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
摘要翻译： 一种具有最小不吸收质量的新型高抗拉强度半吸收复合缝合线。 缝线具有由生物可吸收聚合物制成的芯。 芯由编织护套覆盖。 编织护套由可吸收纱线和生物可吸收纱线制成。 生物可吸收纱线由生物可吸收聚合物的至少一根丝制成。 非吸收性纱线由至少一根超高分子量聚乙烯丝制成。
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公开(公告)号：US4579696A
公开(公告)日：1986-04-01
申请号：US676098
申请日：1984-11-29
申请人： Robert C. Di Luccio
发明人： Robert C. Di Luccio
CPC分类号： B32B27/32 , B32B27/322
摘要： A transparent, elastomeric, composite film structure having a core ethylene/vinyl acetate copolymer and outer layers of a low density ethylene homopolymer or copolymer with a small amount of another .alpha.-olefin or vinyl acetate is made by coextrusion of the polymers in a three-layer combining adapter and quenching on a chill roll. This film structure is useful as a wrapping material, especially for heat-sensitive articles.
摘要翻译： 具有核心乙烯/乙酸乙烯酯共聚物和低密度乙烯均聚物或少量另外的α-烯烃或乙酸乙烯酯的共聚物的透明的，弹性体的复合膜结构是通过三元共聚物共挤出而制成的， 层组合适配器和淬火辊上的淬火。 该膜结构可用作包裹材料，特别是对于热敏性物品。
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公开(公告)号：US08568449B2
公开(公告)日：2013-10-29
申请号：US13330741
申请日：2011-12-20
IPC分类号： A61B17/04
CPC分类号： A61L17/10 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00004 , A61B2017/00893 , A61B2017/0414 , A61B2017/0458 , A61B2017/06171 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/105 , A61L17/145 , A61L2300/402 , A61L2300/406 , A61L2300/41 , D04C1/12 , D10B2509/04
摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
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