公开(公告)号：US20220072780A1

公开(公告)日：2022-03-10

申请号：US17514633

申请日：2021-10-29

Applicant: 3D SYSTEMS, INC.

Inventor： Ricardo SOLORZANO ,  Eza KOCH ,  Guillaume ROBITAILLE-BEAUMIER

IPC: B29C64/209 ,  A61L27/52 ,  B29C64/106 ,  B29C64/112 ,  B29C64/295 ,  B33Y30/00 ,  C12M3/00 ,  C12N5/00 ,  C12N5/071 ,  B29C64/336

Abstract: The present invention relates to a three-dimensional bioprinter for printing and/or patterning a single type or multiple types of cells into different geometrical arrangements and other three-dimensional structures, such as tissues. The bioprinter comprises multiple heads that can each be loaded with a different cartridge containing a biomaterial or biological material such as cells in a solution or cells in a hydrogel. Each bioprinter head and cartridge has the ability to heat or cool using Peltier technology. The bioprinter also has the ability to auto calibrate on a bed plate configured to accept a petri dish or microtiter plate.

公开(公告)号：US20210379815A1

公开(公告)日：2021-12-09

申请号：US17341872

申请日：2021-06-08

Applicant: 3D SYSTEMS, INC.

Inventor： Taciana Leticia WOELLNER DUARTE PEREIRA ,  Thomas CASTNER ,  Madeline WINTER ,  Ricardo SOLORZANO

IPC: B29C64/112 ,  B29C64/245 ,  B29C64/255 ,  B29C64/209 ,  B29C64/264 ,  B29C64/386 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/00

Abstract: Disclosed are systems and methods for a bioprinter capable of printing an object having biological components. In some embodiments, the bioprinter includes a modular print bed having a recessed area configured to receive a variable insert and a printer head positioned above the modular print bed. In some embodiments, the printer head has a cartridge for receiving and holding a biomaterial, and an extruder configured to extrude biomaterials from the cartridge onto a portion of the variable insert. The variable insert may include functional elements (e.g., heating, cooling, photocuring) and/or receiving elements (e.g., well plates).

公开(公告)号：US20230390994A1

公开(公告)日：2023-12-07

申请号：US18034259

申请日：2021-07-19

Applicant: 3D SYSTEMS, INC.

Inventor： Ricardo SOLORZANO ,  Nicholas MCKNIGHT

IPC: B29C64/106 ,  B29C64/209

CPC classification number: B29C64/106 ,  B33Y10/00 ,  B29C64/209

Abstract: Disclosed is a bioextruder assembly capable of “retro-fit” an existing three-dimensional (3D) printer such that it is capable of printing biomaterials. The bioextruder assembly may be modular, self-contained, and configured as “plug-and-play” unit. In some embodiments, the bioextruder assembly may be configured for use in zero-gravity environments such as space and configured to engage with existing 3D printers in space. In some embodiments the bioextruder assembly includes an extruder configured to extrude bio-materials stored in a syringe that is coupled to the extruder, and a converter. The converter may include an electromechanical coupling component that couples the converter to a three-dimensional printer system, and a motor configured to actuate the extrusion of bio-materials stored in the syringe based on signals received from the three-dimensional printing system via the electromechanical coupling component. In some embodiments, the converter may be configured to reversibly attach to the extruder via an attachment element.