公开(公告)号：US20160083470A1

公开(公告)日：2016-03-24

申请号：US14866105

申请日：2015-09-25

Applicant: AMGEN INC.

Inventor： Tara ARVEDSON ,  Gregory DYAS ,  James B. ROTTMAN ,  Barbra SASU ,  Xiao-juan BI ,  Grace Ki Jeong LEE ,  Jackie Z. SHENG

IPC: C07K16/28 ,  A61K38/18 ,  A61K39/395

CPC classification number: C07K16/28 ,  A61K38/1816 ,  A61K39/3955 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/70 ,  C07K2317/76 ,  G01N33/6872 ,  G01N33/90 ,  G01N2800/00

Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.

Abstract translation: 提供了用于治疗铁体内平衡障碍的组合物。 更具体地，提供抗铁绿蛋白抗体，含有此类抗体的组合物，相应的核酸，载体和宿主细胞，以及制备此类抗体的方法。

公开(公告)号：US20230124464A1

公开(公告)日：2023-04-20

申请号：US17751586

申请日：2022-05-23

Applicant: Amgen, Inc. ,  Kite Pharma, Inc.

Inventor： Alice BAKKER ,  Lawren WU ,  Tara ARVEDSON ,  Jed J. WILTZIUS ,  Ruben Alvarez RODRIGUEZ

IPC: A61K35/17 ,  C07K16/28 ,  C12N9/12 ,  A61P37/06 ,  A61P35/02 ,  C07K14/725 ,  C07K14/705 ,  C12N15/62 ,  C12N15/85

Abstract: Antigen binding molecules, chimeric receptors, and engineered immune cells to FLT3 are disclosed in accordance with the invention. The invention further relates to vectors, compositions, and methods of treatment and/or detection using the FLT3 antigen binding molecules and engineered immune cells.

公开(公告)号：US20230331855A1

公开(公告)日：2023-10-19

申请号：US18178086

申请日：2023-03-03

Applicant: KITE PHARMA, INC. ,  AMGEN INC.

Inventor： Jed WILTZIUS ,  Ruben ALVAREZ RODRIGUEZ ,  Alice BAKKER ,  Lawren WU ,  Tara ARVEDSON

IPC: C07K16/28 ,  C07K14/435 ,  C07K14/725 ,  C07K14/705 ,  C12N15/86

CPC classification number: C07K16/2851 ,  C07K14/435 ,  C07K14/7051 ,  C07K14/70517 ,  C07K14/70521 ,  C12N15/86 ,  C07K2317/622 ,  A61K2039/505

Abstract: Antigen binding molecules, chimeric receptors, and engineered immune cells are disclosed in accordance with the invention. The invention further relates to vectors, compositions, and methods of treatment and/or detection using the antigen binding molecules and engineered immune cells.