公开(公告)号：US20250127696A1

公开(公告)日：2025-04-24

申请号：US18917401

申请日：2024-10-16

Applicant: AMOREPACIFIC CORPORATION

Inventor： Kyuhan KIM ,  Yeonju CHO ,  Suhyeon CHOI ,  Hyunjung CHOI

IPC: A61K8/37 ,  A61Q19/08

Abstract: A composition capable of preventing or improving skin aging by controlling a senescence biomarker of melanocytes is disclosed. The composition includes a thymol ester-based compound as an effective ingredient, whereby when applied to a subject in which skin cells are flattened or enlarged, or β-galactosidase of melanocytes is activated, it can exhibit the effect of preventing or improving skin aging.

公开(公告)号：US20180177699A1

公开(公告)日：2018-06-28

申请号：US15739534

申请日：2016-06-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Bum-Ho BIN ,  Eun-Gyung CHO ,  Eun-Jeong CHOI ,  Sungtae KIM ,  Suhyeon CHOI ,  Taeryong LEE

IPC: A61K8/49 ,  A61Q19/02 ,  G01N33/50

CPC classification number: A61K8/494 ,  A61K8/49 ,  A61K8/4946 ,  A61K8/60 ,  A61K8/73 ,  A61K9/0014 ,  A61K9/0095 ,  A61K9/06 ,  A61K9/1652 ,  A61K9/205 ,  A61K9/4875 ,  A61K31/18 ,  A61K31/4178 ,  A61K47/06 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/42 ,  A61Q19/02 ,  G01N33/5044

Abstract: Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocytes by inhibiting the amount of secretion of exosomes to be secreted from melanocytes, and consequently inhibits the generation of melanin through the apoptosis of melanocytes, thereby exhibiting a skin whitening effect.