公开(公告)号：US20180256488A1

公开(公告)日：2018-09-13

申请号：US15760882

申请日：2016-09-26

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun-Jeong CHOI ,  Yonghee LEE ,  Seung Hyun SHIN ,  Kyeonghwan HWANG ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/9789 ,  A61Q7/00

CPC classification number: A61K8/9789 ,  A61K8/14 ,  A61K36/258 ,  A61Q7/00

Abstract: Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated from ginseng root. The composition contains ginseng-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

公开(公告)号：US20190041383A1

公开(公告)日：2019-02-07

申请号：US15764615

申请日：2016-09-29

Applicant: AMOREPACIFIC CORPORATION

Inventor： Suh-Yeon CHOI ,  Eunkyung LEE ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: G01N33/50 ,  C12N5/071 ,  C12N13/00

Abstract: Disclosed in the present specification are a method for preparing senescent melanocytes, senescent cells prepared by the preparation method and a method for screening a senescence-alleviating or skin whitening material by using the senescent cells. The cells can be used for studying a cell senescence phenomenon and a pigmentation mechanism, which are caused by the accumulation of UV ray stimulation. Particularly, the cells are useful since a material having both senescence-alleviating and skin whitening effects can be screened.

公开(公告)号：US20210177919A1

公开(公告)日：2021-06-17

申请号：US16759892

申请日：2018-10-05

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun-Gyung CHO ,  Wanil KIM ,  Tae Ryong LEE

IPC: A61K35/747 ,  A61K8/14 ,  A23L33/135 ,  A61K8/99

Abstract: The present specification discloses an immunomodulatory composition comprising Lactobacillus-derived extracellular vesicles as an active ingredient. The Lactobacillus may be Lactobacillus plantarum. The composition has the effects of inducing differentiation into M2-type macrophages and reducing expression of at least one member selected from the group consisting of CCR2, SOCS3 and HLA-DRα, which are M1-type macrophage differentiation markers.

公开(公告)号：US20180263871A1

公开(公告)日：2018-09-20

申请号：US15760819

申请日：2016-09-23

Applicant: AMOREPACIFIC CORPORATION

Inventor： Suh-Yeon CHOI ,  Eun-Jeong CHOI ,  Bum-Ho BIN ,  Kyeonghwan HWANG ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/14 ,  A61Q19/02 ,  A61K8/9789

CPC classification number: A61K8/14 ,  A61K8/9789 ,  A61K36/258 ,  A61K2800/413 ,  A61Q19/02

Abstract: Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

公开(公告)号：US20180256490A1

公开(公告)日：2018-09-13

申请号：US15760908

申请日：2016-09-26

Applicant: AMOREPACIFIC CORPORATION

Inventor： Sung Tae KIM ,  Yonghee LEE ,  Seung Hyun SHIN ,  Hyun Gee LEE ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/99 ,  A61Q7/00 ,  A61K8/14

CPC classification number: A61K8/99 ,  A61K8/14 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61P17/14 ,  A61Q7/00

Abstract: The present specification discloses a composition for preventing hair loss or promoting hair growth comprising, as an active ingredient, extracellular follicles derived from lactic acid bacteria, and a method for preparing the extracellular follicles derived from lactic acid bacteria. The composition has an effect of preventing and prohibiting hair from falling off from the scalp or becoming thin or tapered. In addition, the composition has an effect of implementing a hair growth function for generating new hair, or a function for promoting the hair growth, as well as a function of promoting a delay from an anagen to a catagen phase of a hair cycle and a function of growing the existing hair healthy.

公开(公告)号：US20180177699A1

公开(公告)日：2018-06-28

申请号：US15739534

申请日：2016-06-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Bum-Ho BIN ,  Eun-Gyung CHO ,  Eun-Jeong CHOI ,  Sungtae KIM ,  Suhyeon CHOI ,  Taeryong LEE

IPC: A61K8/49 ,  A61Q19/02 ,  G01N33/50

CPC classification number: A61K8/494 ,  A61K8/49 ,  A61K8/4946 ,  A61K8/60 ,  A61K8/73 ,  A61K9/0014 ,  A61K9/0095 ,  A61K9/06 ,  A61K9/1652 ,  A61K9/205 ,  A61K9/4875 ,  A61K31/18 ,  A61K31/4178 ,  A61K47/06 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/42 ,  A61Q19/02 ,  G01N33/5044

Abstract: Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocytes by inhibiting the amount of secretion of exosomes to be secreted from melanocytes, and consequently inhibits the generation of melanin through the apoptosis of melanocytes, thereby exhibiting a skin whitening effect.