公开(公告)号：US20230250487A1

公开(公告)日：2023-08-10

申请号：US18296915

申请日：2023-04-06

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Rizal HARIADI ,  Hao YAN ,  Swarup DEY

IPC: C12Q1/6886 ,  C12Q1/682 ,  C12Q1/6881

CPC classification number: C12Q1/6886 ,  C12Q1/682 ,  C12Q1/6881 ,  C12Q1/6841 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Disclosed herein are methods and compositions comprising transmembrane nanosensors, and their use to identify, detect, label, and isolate cells. In some embodiments, the nanosensors may be used in conjunction with a hybridization chain reaction to amplify a signal, and to aid in the detection, identification, labeling or isolation of cells.

公开(公告)号：US20210032775A1

公开(公告)日：2021-02-04

申请号：US16762024

申请日：2018-11-30

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Ashwin GOPINATH ,  Paul ROTHEMUND ,  Rishabh SHETTY ,  Rizal HARIADI

IPC: C40B40/06 ,  B01J19/00

Abstract: Embodiments of the present disclosure relate generally to single molecule arrays. More particularly, the present disclosure provides materials and methods for generating single molecule arrays using bottom-up self-assembly processes. Materials and methods of the present disclosure can be used to generate single molecule arrays with nanoapertures (e.g., zero mode waveguides) and for carrying out rapid, point-of-care biomolecule detection and quantification.