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公开(公告)号：US20200299246A1
公开(公告)日：2020-09-24
申请号：US16892786
申请日：2020-06-04
Applicant: Calico Life Sciences LLC , AbbVie Inc.
Inventor： Geoff T. Halvorsen , Jennifer M. Frost , Philip R. Kym
IPC: C07D285/10
Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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公开(公告)号：US10053474B2
公开(公告)日：2018-08-21
申请号：US15588037
申请日：2017-05-05
Applicant: AbbVie Inc.
Inventor： Jaclyn Chau , Hui-Ju J. Chen , David A. DeGoey , John Hartung , Nathan Ide , Vikram Kalthod , Allan C. Krueger , Yi-Yin Ku , Tongmei Li , John T. Randolph , Rolf Wagner , Geoff T. Halvorsen , Christopher C. Marvin , Eric Voight , Brian S. Brown , Steven R. Martinez , Anurupa Shrestha , Howard R. Heyman
IPC: A61K31/675 , C07F9/02 , C07F9/08 , C07F9/6512 , C07H19/10
CPC classification number: C07F9/08 , C07F9/6512 , C07H19/10
Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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公开(公告)号：US20170057981A1
公开(公告)日：2017-03-02
申请号：US15254342
申请日：2016-09-01
Applicant: AbbVie Inc.
Inventor： Hui-Ju J. Chen , David A. DeGoey , John Hartung , Nathan Ide , Vikram Kalthod , Allan C. Krueger , Yi-Yin Ku , Tongmei Li , John T. Randolph , Rolf Wagner , Jaclyn Chau , Geoff T. Halvorsen , Christopher C. Marvin , Eric Voight
IPC: C07F9/08
CPC classification number: C07F9/08 , C07F9/6512 , C07H19/10
Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
Abstract translation: 本发明的特征在于有效抑制丙型肝炎病毒（“HCV”）聚合酶的活性的化合物。 本发明还涉及制备这些化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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Patent Agency Ranking
公开(公告)号：US20250122160A1
公开(公告)日：2025-04-17
申请号：US18647757
申请日：2024-04-26
Applicant: Calico Life Sciences LLC , AbbVie Inc.
Inventor： Philip R. Kym , Jennifer M. Frost , Christos Economou , Andrew Bogdan , Stacy Fosu , Zhaoming Xiong , Spencer O. Scholz , Eric Allan Voight , Elliot P. Farney , Mark A. Matulenko , Matthew J. O'Connor , Christina Baumgartner , Qingwei Zhang , Reza Shiroodi , Jason R. Abbott , Geoff T. Halvorsen
IPC: C07D285/06 , A61K31/433 , A61K31/4439 , A61K31/454 , A61K31/4725 , A61K31/501 , C07D417/04 , C07D417/12 , C07D417/14
Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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公开(公告)号：US20230019236A1
公开(公告)日：2023-01-19
申请号：US17807292
申请日：2022-06-16
Applicant: Calico Life Sciences LLC , AbbVie Inc.
Inventor： Elliot P. Farney , Reza Shiroodi , Zhaoming Xiong , Qingwei Zhang , Matthew J. O'Connor , Geoff T. Halvorsen , Hongyu Zhao , Christina Baumgartner , Jennifer M. Frost , Philip R. Kym , Jason R. Abbott , Andrew Bogdan , Christos Economou , Xueqing Wang
IPC: A61K31/433 , A61K39/395 , A61P35/00 , C07D417/10 , A61K31/5377 , C07D285/06
Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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公开(公告)号：US10851073B2
公开(公告)日：2020-12-01
申请号：US16892786
申请日：2020-06-04
Applicant: Calico Life Sciences LLC , AbbVie Inc.
Inventor： Geoff T. Halvorsen , Jennifer M. Frost , Philip R. Kym
IPC: C07D285/10
Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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公开(公告)号：US20180022763A1
公开(公告)日：2018-01-25
申请号：US15588037
申请日：2017-05-05
Applicant: AbbVie Inc.
Inventor： Jaclyn Chau , Hui-Ju J. Chen , David A. DeGoey , John Hartung , Nathan Ide , Vikram Kalthod , Allan C. Krueger , Yi-Yin Ku , Tongmei Li , John T. Randolph , Rolf Wagner , Geoff T. Halvorsen , Christopher C. Marvin , Eric Voight , Brian S. Brown , Steven R. Martinez , Anurupa Shrestha , Howard R. Heyman
IPC: C07F9/08 , C07F9/6512 , C07H19/10
CPC classification number: C07F9/08 , C07F9/6512 , C07H19/10
Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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公开(公告)号：US09676797B2
公开(公告)日：2017-06-13
申请号：US15254342
申请日：2016-09-01
Applicant: AbbVie Inc.
Inventor： Hui-Ju J. Chen , David A. DeGoey , John Hartung , Nathan Ide , Vikram Kalthod , Allan C. Krueger , Yi-Yin Ku , Tongmei Li , John T. Randolph , Rolf Wagner , Jaclyn Chau , Geoff T. Halvorsen , Christopher C. Marvin , Eric Voight
IPC: A61K31/675 , C07F9/02 , C07F9/08 , C07F9/6512
CPC classification number: C07F9/08 , C07F9/6512 , C07H19/10
Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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