公开(公告)号：US20150315283A1

公开(公告)日：2015-11-05

申请号：US14687392

申请日：2015-04-15

Applicant: AbbVie Inc.

Inventor： Tariq Ghayur ,  Peter C. Isakson ,  Lisa M. Olson ,  Chengbin Wu ,  Margaret Hugunin ,  Rajesh V. Kamath ,  Carolyn A. Cuff ,  Hamish J. Allen

IPC: C07K16/28 ,  C07K16/22 ,  G01N33/68 ,  A61K39/395 ,  A61K45/06 ,  C07K16/24 ,  A61K47/48

CPC classification number: C07K16/2887 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/6845 ,  A61K2039/505 ,  A61K2039/70 ,  C07K16/22 ,  C07K16/241 ,  C07K16/244 ,  C07K16/245 ,  C07K16/247 ,  C07K16/248 ,  C07K16/2866 ,  C07K16/468 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/35 ,  C07K2317/64 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/6869 ,  G01N2333/545 ,  Y02A50/386 ,  Y02A50/41 ,  Y02A50/412 ,  Y02A50/58

Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.