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公开(公告)号:US09663587B2
公开(公告)日:2017-05-30
申请号:US14262653
申请日:2014-04-25
Applicant: AbbVie Inc.
Inventor: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC: C07K16/46 , C07K16/24 , A61K39/395 , A61K39/00
CPC classification number: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号:US09655964B2
公开(公告)日:2017-05-23
申请号:US13659666
申请日:2012-10-24
Applicant: AbbVie Inc.
Inventor: Jennifer Perez , Suju Zhong , Lucia Eaton , Anca Clabbers , Chung-Ming Hsieh , Lorenzo Benatuil , Yuliya Kutskova , John E. Memmott , Margaret Hugunin , Alyssa Brito
CPC classification number: A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/241 , C07K16/244 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/5308
Abstract: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.
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公开(公告)号:US09481735B2
公开(公告)日:2016-11-01
申请号:US14261257
申请日:2014-04-24
Applicant: AbbVie Inc.
Inventor: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC: C07K16/24 , C07K16/46 , A61K39/395 , A61K39/00
CPC classification number: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
Abstract translation: 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号:US09481736B2
公开(公告)日:2016-11-01
申请号:US14263724
申请日:2014-04-28
Applicant: AbbVie Inc.
Inventor: Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC: C07K16/46 , C07K16/24 , A61K39/395 , A61K39/00
CPC classification number: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
Abstract: Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
Abstract translation: 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗,预防和诊断IL-17相关疾病和用于检测细胞,组织,样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号:US20150315283A1
公开(公告)日:2015-11-05
申请号:US14687392
申请日:2015-04-15
Applicant: AbbVie Inc.
Inventor: Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish J. Allen
CPC classification number: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/58
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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6.IL-1 ALPHA DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
Title translation: IL-1 ALPHA双变量域免疫球蛋白及其用途公开(公告)号:US20140335014A1
公开(公告)日:2014-11-13
申请号:US14248223
申请日:2014-04-08
Applicant: AbbVie, Inc.
Inventor: Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish Allen
CPC classification number: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/58
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白,制备方法,具体涉及用于预防,诊断和/或治疗疾病的用途。
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公开(公告)号:US20140079705A1
公开(公告)日:2014-03-20
申请号:US14082502
申请日:2013-11-18
Applicant: Abbvie Inc.
Inventor: Chung-ming Hsieh , Jennifer Perez , Lorenzo Benatuil , Yuliya Kutskova , John Memmott , Suju Zhong , Lucia Eaton , Margaret Hugunin , Alyssa Brito , Anca Clabbers
CPC classification number: A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/241 , C07K16/244 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/5308
Abstract: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.
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