公开(公告)号：US20180022763A1

公开(公告)日：2018-01-25

申请号：US15588037

申请日：2017-05-05

Applicant: AbbVie Inc.

Inventor： Jaclyn Chau ,  Hui-Ju J. Chen ,  David A. DeGoey ,  John Hartung ,  Nathan Ide ,  Vikram Kalthod ,  Allan C. Krueger ,  Yi-Yin Ku ,  Tongmei Li ,  John T. Randolph ,  Rolf Wagner ,  Geoff T. Halvorsen ,  Christopher C. Marvin ,  Eric Voight ,  Brian S. Brown ,  Steven R. Martinez ,  Anurupa Shrestha ,  Howard R. Heyman

IPC: C07F9/08 ,  C07F9/6512 ,  C07H19/10

CPC classification number: C07F9/08 ,  C07F9/6512 ,  C07H19/10

Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

公开(公告)号：US10053474B2

公开(公告)日：2018-08-21

申请号：US15588037

申请日：2017-05-05

Applicant: AbbVie Inc.

Inventor： Jaclyn Chau ,  Hui-Ju J. Chen ,  David A. DeGoey ,  John Hartung ,  Nathan Ide ,  Vikram Kalthod ,  Allan C. Krueger ,  Yi-Yin Ku ,  Tongmei Li ,  John T. Randolph ,  Rolf Wagner ,  Geoff T. Halvorsen ,  Christopher C. Marvin ,  Eric Voight ,  Brian S. Brown ,  Steven R. Martinez ,  Anurupa Shrestha ,  Howard R. Heyman

IPC: A61K31/675 ,  C07F9/02 ,  C07F9/08 ,  C07F9/6512 ,  C07H19/10

CPC classification number: C07F9/08 ,  C07F9/6512 ,  C07H19/10

Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.