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公开(公告)号：US11562484B2
公开(公告)日：2023-01-24
申请号：US17127651
申请日：2020-12-18
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi , Parisa Rabbani , Hugang Ren
Abstract: Systems and methods are presented for providing a machine learning model for segmenting an optical coherence tomography (OCT) image. A first OCT image is obtained, and then labeled with identified boundaries associated with different tissues in the first OCT image using a graph search algorithm. Portions of the labeled first OCT image are extracted to generate a first plurality of image tiles. A second plurality of image tiles is generated by manipulating at least one image tile from the first plurality of image tiles, such as by rotating and/or flipping the at least one image tile. The machine learning model is trained using the first plurality of image tiles and the second plurality of image tiles. The trained machine learning model is used to perform segmentation in a second OCT image.
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公开(公告)号：US20200367744A1
公开(公告)日：2020-11-26
申请号：US16876960
申请日：2020-05-18
Applicant: Alcon Inc.
Inventor： Brent Duchon , Muhammad K. Al-Qaisi , Richard J. Michaels , Steve X. Chen
Abstract: Systems and methods are disclosed for performing ophthalmic optical coherence tomography with multiple resolutions. In some embodiments, a system comprises a light source, an output lens, and a set of optical components between the light source and the output lens, the set of optical components comprising an afocal zoom telescope. The set of optical components is adapted to provide imaging both at a first field of view with a first resolution and at a second field of view with a second resolution, wherein the first field of view is wider than the second field of view and the second resolution is higher than the first resolution. A method of performing ophthalmic optical coherence tomography with multiple resolutions may be performed using one or more of the systems described herein.
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公开(公告)号：US11602272B2
公开(公告)日：2023-03-14
申请号：US16876960
申请日：2020-05-18
Applicant: Alcon Inc.
Inventor： Brent Duchon , Muhammad K. Al-Qaisi , Richard J. Michaels , Steve X. Chen
IPC: G02B13/22 , A61B3/10 , G01B9/02015 , G01B9/02091 , G02B13/06 , G02B15/15 , G02B27/10
Abstract: Systems and methods are disclosed for performing ophthalmic optical coherence tomography with multiple resolutions. In some embodiments, a system comprises a light source, an output lens, and a set of optical components between the light source and the output lens, the set of optical components comprising an afocal zoom telescope. The set of optical components is adapted to provide imaging both at a first field of view with a first resolution and at a second field of view with a second resolution, wherein the first field of view is wider than the second field of view and the second resolution is higher than the first resolution. A method of performing ophthalmic optical coherence tomography with multiple resolutions may be performed using one or more of the systems described herein.
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公开(公告)号：US10767973B2
公开(公告)日：2020-09-08
申请号：US16173146
申请日：2018-10-29
Applicant: Alcon Inc.
Inventor： Bing Wang , Muhammad K. Al-Qaisi , Hugang Ren
Abstract: Techniques and apparatus for producing sampled Optical Coherence Tomography (OCT) interference signals without aliasing, based on a swept-source OCT interference signal. An example apparatus comprises a k-clock circuit configured to selectively output a k-clock signal at any of a plurality of k-clock frequencies ranging from a minimum k-clock frequency to a maximum k-clock frequency, and an anti-aliasing filter configured to filter a swept-source OCT interference signal, to produce a filtered OCT interference signal, where the anti-aliasing filter has a cut-off frequency greater than one-half the minimum k-clock frequency but less than the minimum k-clock frequency. The apparatus further comprises an analog-to-digital (A/D) converter circuit configured to sample the filtered OCT interference signal at twice the k-clock frequency, to produce a sampled OCT interference signal. In some embodiments, the A/D converter circuit samples the filtered OCT interference signal at both rising and falling edges of the k-clock signal.
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公开(公告)号：US20230124674A1
公开(公告)日：2023-04-20
申请号：US18068978
申请日：2022-12-20
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi , Parisa Rabbani , Hugang Ren
Abstract: Systems and methods are presented for providing a machine learning model for segmenting an optical coherence tomography (OCT) image. A first OCT image is obtained, and then labeled with identified boundaries associated with different tissues in the first OCT image using a graph search algorithm. Portions of the labeled first OCT image are extracted to generate a first plurality of image tiles. A second plurality of image tiles is generated by manipulating at least one image tile from the first plurality of image tiles, such as by rotating and/or flipping the at least one image tile. The machine learning model is trained using the first plurality of image tiles and the second plurality of image tiles. The trained machine learning model is used to perform segmentation in a second OCT image.
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Patent Agency Ranking
6.发明授权公开(公告)号：US10966607B2
公开(公告)日：2021-04-06
申请号：US16149380
申请日：2018-10-02
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi
Abstract: Techniques for measuring optical aberrations of the eye are disclosed. An example method comprises positioning the eye in a measurement location adjacent to a measurement arm of an optical coherence tomography (OCT) interferometer apparatus, so that source light from the measurement arm passes into the anterior segment of the eye and detecting an interference pattern, the interference pattern resulting from a combination of light reflected from the eye and light reflected from a reference arm of the OCT interferometer apparatus. Based on the interference pattern, an optical delay between a reference surface in the anterior segment of the eye and a measured surface in the eye is calculated, the reference surface being the anterior surface of the cornea or the lens, wherein said calculating comprises measuring an optical phase shift between the reference surface and the measured surface, based on the detected interference pattern.
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公开(公告)号：US20210192732A1
公开(公告)日：2021-06-24
申请号：US17127651
申请日：2020-12-18
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi , Parisa Rabbani , Hugang Ren
Abstract: Systems and methods are presented for providing a machine learning model for segmenting an optical coherence tomography (OCT) image. A first OCT image is obtained, and then labeled with identified boundaries associated with different tissues in the first OCT image using a graph search algorithm. Portions of the labeled first OCT image are extracted to generate a first plurality of image tiles. A second plurality of image tiles is generated by manipulating at least one image tile from the first plurality of image tiles, such as by rotating and/or flipping the at least one image tile. The machine learning model is trained using the first plurality of image tiles and the second plurality of image tiles. The trained machine learning model is used to perform segmentation in a second OCT image.
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公开(公告)号：US20210186753A1
公开(公告)日：2021-06-24
申请号：US17126899
申请日：2020-12-18
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi , Paul Hallen
IPC: A61F9/008
Abstract: The present disclosure provides a laser treatment system that includes an optical coherence tomography (OCT) imaging system that generates a plurality of profile depth scans and executes instructions on a processor to detect a position, a volume, or a combination thereof, of a media opacity in an eye based on the plurality of profile depth scans. The system further includes a three-dimensional (3D) eye tracker that executes instructions on the processor to track the position, the volume, or a combination thereof, of the media opacity in the eye based on the plurality of profile depth scans. The system also includes a laser system that includes a treatment laser and that precisely targets a plurality of ultra-short laser pulses generated by the treatment laser at the media opacity in the eye to at least partially remove the media opacity.
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公开(公告)号：US20230218162A1
公开(公告)日：2023-07-13
申请号：US18174469
申请日：2023-02-24
Applicant: Alcon Inc.
Inventor： Guy Holland , Muhammad K. Al-Qaisi
IPC: A61B3/10 , A61F9/008 , G01B9/02091 , A61B5/00 , G02B6/02 , G01B9/02056
CPC classification number: A61B3/102 , A61F9/008 , G01B9/02091 , A61B5/0066 , G02B6/02395 , G01B9/02057 , A61F2009/00851 , A61B2560/0223
Abstract: An OCT imaging system may include an OCT light source operable to emit an OCT light beam, and a beam splitter operable to split the OCT light beam into a sample beam, transferred to a sample arm waveguide, and a reference beam, transferred to a reference arm waveguide. The sample arm waveguide and the reference arm waveguide may be coupled together within a cladding, wherein the cladding improves a calibration of a generated OCT image by fixing axial movement of the sample arm and reference arm waveguides relative to one another. By routing long reference and sample arm waveguide fibers together in the OCT system using a sheath/cladding, OCT image offset due to asymmetrical fiber stretching can be minimized or eliminated.
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公开(公告)号：US20230021386A1
公开(公告)日：2023-01-26
申请号：US17938616
申请日：2022-10-06
Applicant: Alcon Inc.
Inventor： Muhammad K. Al-Qaisi , Tomas Sedlacek , Joseph T. Traynor , Antonije M. Radojevic , Todd Schernig , Sahar Hosseinzadeh Kassani
IPC: A61B3/10 , G01B9/02015 , G01B9/02
Abstract: An Optical Coherence Tomography receiver may include prisms, polarizing beam splitters, reflectors, lenses, and a photodetector array arranged in a compact package. Sample and reference beams are combined into an interference beam and split in two. The two resulting interference beams are then split into two polarization sates each. The optical path lengths for both pairs of interference beams with the same polarization state are equal or nearly equal.
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