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公开(公告)号:US06204014B1
公开(公告)日:2001-03-20
申请号:US09191879
申请日:1998-11-13
申请人: Alison F Chalker , David J Holmes , Karen A Ingraham , Deborah D Jaworski , Anna L Lenox , Earl W May , Marie J Mazzulla , Jennifer Ray , Min Wang , Richard L Warren, Jr.
发明人: Alison F Chalker , David J Holmes , Karen A Ingraham , Deborah D Jaworski , Anna L Lenox , Earl W May , Marie J Mazzulla , Jennifer Ray , Min Wang , Richard L Warren, Jr.
IPC分类号: C12P2106
CPC分类号: C12N9/90 , A61K38/00 , C07K2319/00
摘要: The invention provides DnaB polypeptides and polynucleotides encoding DnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DnaB polypeptides to screen for anibacterial compounds.
摘要翻译: 本发明提供DnaB多肽和编码DnaB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用DnaB多肽来筛选细菌化合物的方法。
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公开(公告)号:US06218528B1
公开(公告)日:2001-04-17
申请号:US09078691
申请日:1998-05-14
申请人: Nicola G Wallis , Min Wang , Magdalena Zalacain , Sanjoy Biswas , James Raymond Brown , Alison Frances Chalker , David John Holmes , Karen A Ingraham , Deborah D Jaworski , Jennifer Ray , Lisa K Shilling
发明人: Nicola G Wallis , Min Wang , Magdalena Zalacain , Sanjoy Biswas , James Raymond Brown , Alison Frances Chalker , David John Holmes , Karen A Ingraham , Deborah D Jaworski , Jennifer Ray , Lisa K Shilling
IPC分类号: C07H2104
CPC分类号: C12N9/0006 , A61K38/00 , A61K39/00 , C12Y101/01158
摘要: The invention provides MurB polypeptides and polynucleotides encoding MurB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了MurB多肽和编码MurB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用MurB多肽筛选抗菌化合物的方法。
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公开(公告)号:US06238882B1
公开(公告)日:2001-05-29
申请号:US09104068
申请日:1998-06-24
申请人: Jason Craig Fedon , Deborah D Jaworski , Howard Kallender , Anna Lisa Lenox , Leslie Marie Palmer , Min Wang
发明人: Jason Craig Fedon , Deborah D Jaworski , Howard Kallender , Anna Lisa Lenox , Leslie Marie Palmer , Min Wang
IPC分类号: C12P2106
CPC分类号: C07K14/3156 , A61K38/00 , A61K48/00 , C07K2319/00
摘要: The invention provides gidA1 polypeptides and polynucleotides encoding gidA1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidA1 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供gidA1多肽和编码gidA1多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用gidA1多肽筛选抗菌化合物的方法。
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公开(公告)号:US06548281B1
公开(公告)日:2003-04-15
申请号:US09642000
申请日:2000-08-18
申请人: Karen M O'Dwyer , Deborah D Jaworski , Jeffrey L Mooney , Lisa K Shilling , John Peter Throup , Nicola Gail Wallis , Yi Yi Zhong , Min Wang
发明人: Karen M O'Dwyer , Deborah D Jaworski , Jeffrey L Mooney , Lisa K Shilling , John Peter Throup , Nicola Gail Wallis , Yi Yi Zhong , Min Wang
IPC分类号: C12N912
CPC分类号: G01N33/573 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K14/31 , C12N9/12
摘要: The invention provides Histidine Kinase polypeptides and polynucleotides encoding Histidine Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine Kinase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供组氨酸激酶多肽和编码组氨酸激酶多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用组氨酸激酶多肽筛选抗菌化合物的方法。
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