公开(公告)号：US20250098728A1

公开(公告)日：2025-03-27

申请号：US18975272

申请日：2024-12-10

Applicant: Altria Client Services LLC

Inventor： Yahya KARGA ,  James POWELL ,  Dongmei XU ,  James A. STRICKLAND ,  Ujwala WAREK

IPC: A24B15/22 ,  A24B13/00 ,  A24B15/10 ,  A24B15/18 ,  A24B15/28

Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.

公开(公告)号：US20240117370A1

公开(公告)日：2024-04-11

申请号：US18517109

申请日：2023-11-22

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A. STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82 ,  A24B13/00

CPC classification number: C12N15/8225 ,  A24B13/00 ,  C12N15/8218 ,  C12N15/8243 ,  C12N15/8261

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20220395014A1

公开(公告)日：2022-12-15

申请号：US17892239

申请日：2022-08-22

Applicant: Altria Client Services LLC

Inventor： Yahya KARGA ,  James POWELL ,  Dongmei XU ,  James A. STRICKLAND ,  Ujwala WAREK

IPC: A24B15/22 ,  A24B15/18 ,  A24B13/00

Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.

公开(公告)号：US20230397651A1

公开(公告)日：2023-12-14

申请号：US18452154

申请日：2023-08-18

Applicant: Altria Client Services LLC

Inventor： Marc W. FARISS ,  Jeffery EDMISTON ,  Dongmei XU ,  Randall BAREN ,  Yahya KARGALIOGLU ,  James A. STRICKLAND

IPC: A24B15/32 ,  A24B13/00 ,  A24B15/30

CPC classification number: A24B15/32 ,  A24B13/00 ,  A24B15/308

Abstract: The method includes adding at least one first chelator to smokeless tobacco in an amount effective to reduce an amount of free calcium in the smokeless tobacco by 20% or more and reduce an amount of free iron in the smokeless tobacco by 60% or more.

公开(公告)号：US20220380788A1

公开(公告)日：2022-12-01

申请号：US17835433

申请日：2022-06-08

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Dong QI ,  Yanxin SHEN ,  Ujwala WAREK ,  James A. STRICKLAND ,  Dongmei XU

IPC: C12N15/82 ,  A01H6/82 ,  A01H5/12 ,  C12Q1/6827

Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20220204981A1

公开(公告)日：2022-06-30

申请号：US17571138

申请日：2022-01-07

Applicant: Altria Client Services LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A. STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82 ,  A24B13/00

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20190037910A1

公开(公告)日：2019-02-07

申请号：US16054351

申请日：2018-08-03

Applicant: Altria Client Services LLC

Inventor： Yahya KARGA ,  James POWELL ,  Dongmei XU ,  James A. STRICKLAND ,  Ujwala WAREK

IPC: A24B15/22 ,  A24B15/18

Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.

公开(公告)号：US20240376488A1

公开(公告)日：2024-11-14

申请号：US18782700

申请日：2024-07-24

Applicant: Altria Client Services LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Dongmei XU ,  James A. STRICKLAND ,  Marcos Fernando de Godoy Lusso

IPC: C12N15/82

Abstract: The present disclosure provides approaches for reducing nicotine. Also provided are tobacco plants with decreased tobacco-specific nitrosamines (TSNAs). The present disclosure further provides modified tobacco plants with low nicotine and increased antioxidant capacity. Further provided are tobacco plants or material with low nicotine and low TSNAs. Also provided is cured tobacco material of the tobacco plants provided herein and tobacco products comprising this cured tobacco material.

公开(公告)号：US20200029522A1

公开(公告)日：2020-01-30

申请号：US16523326

申请日：2019-07-26

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Dong QI ,  Yanxin SHEN ,  Ujwala WAREK ,  James A. STRICKLAND ,  Dongmei XU

IPC: A01H5/12 ,  A01H6/82 ,  C12Q1/6827

Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.