公开(公告)号：US12083110B2

公开(公告)日：2024-09-10

申请号：US18344198

申请日：2023-06-29

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Phillip M. Hulan ,  Shuzhong Zhuang ,  William J. Burke

IPC: A61K31/465 ,  A61K9/00 ,  A61K9/20 ,  A61K45/06 ,  B29C48/00 ,  B29C48/285

CPC classification number: A61K31/465 ,  A61K9/0056 ,  A61K9/2059 ,  A61K9/2095 ,  A61K45/06 ,  B29C48/0022 ,  B29C48/297 ,  B29C2793/0009 ,  B29C2793/009

Abstract: A nicotine lozenge includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and nicotine or a derivative thereof dispersed in the soluble-fiber matrix. A nicotine lozenge may include at least 40 weight percent of soluble fiber. Soluble fiber in a nicotine lozenge may include maltodextrin. The nicotine lozenge is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity of an adult consumer and exposed to saliva. A method of making nicotine lozenges includes forming a molten mixture of at least 40 weight percent soluble fiber, nicotine, and less than 15 weight percent water while maintaining a mixture temperature of less than 150° C. and portioning the molten mixture into a plurality of nicotine lozenges. The ingredients can be mixed to form the molten mixture in an extruder.

公开(公告)号：US11944115B2

公开(公告)日：2024-04-02

申请号：US17380255

申请日：2021-07-20

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Shuzhong Zhuang ,  Diane L. Gee

IPC: A24B15/16 ,  A23G4/06 ,  A24B13/00 ,  A24B15/28 ,  A24B15/30 ,  C07D401/04

CPC classification number: A24B15/16 ,  A23G4/06 ,  A24B13/00 ,  A24B15/285 ,  A24B15/303 ,  C07D401/04

Abstract: This document provides methods and systems for stabilizing nicotine and incorporating nicotine into one or more oral products. This document also provides oral products. Nicotine can be stabilized by mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture. In some cases, a cellulosic fiber-nicotine mixture can be combined with one or more binders and molded into an oral product.

公开(公告)号：US11554099B2

公开(公告)日：2023-01-17

申请号：US16132728

申请日：2018-09-17

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Shuzhong Zhuang ,  Phillip M. Hulan ,  William J. Burke ,  Gerd Kobal

IPC: A61K9/20 ,  A23G3/38 ,  A23G3/42 ,  A61K8/73 ,  A61Q11/00 ,  A23G3/34 ,  A61K9/00

Abstract: A soluble fiber lozenge provided herein includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and one or more additives dispersed in the soluble-fiber matrix. In some cases, a soluble fiber lozenge provided herein includes at least 40 weight percent of soluble fiber. In some cases, soluble fiber in soluble fiber lozenge provided herein can include maltodextrin. The soluble fiber lozenge is adapted to release one or more additives from the body when the body is received within the oral cavity of a consumer and exposed to saliva. A method of making soluble fiber lozenges provided herein includes forming a molten mixture of at least 40 weight percent soluble fiber, one or more additives, and less than 15 weight percent water while maintaining a mixture temperature of less than 200° C. and portioning the molten mixture into a plurality of soluble fiber lozenges. In some cases, the ingredients can be mixed to form the molten mixture in an extruder.

公开(公告)号：US10925309B2

公开(公告)日：2021-02-23

申请号：US16370020

申请日：2019-03-29

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Shuzhong Zhuang ,  Phillip M. Hulan ,  William J. Burke

IPC: A24B15/10 ,  A24B13/00 ,  A24B15/18

Abstract: A tobacco lozenge includes a body configured to be wholly receivable in an oral cavity. The body includes a matrix including a soluble fiber in an amount greater than or equal to 60 weight percent of the body, tobacco plant tissue dispersed in the matrix, and an additive dispersed in the matrix.

公开(公告)号：US10702516B2

公开(公告)日：2020-07-07

申请号：US15954150

申请日：2018-04-16

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Phillip M. Hulan ,  Shuzhong Zhuang ,  William J. Burke

IPC: A61K31/465 ,  A61K9/20 ,  A61K9/00 ,  B29C48/00 ,  A61K45/06 ,  B29C48/285

Abstract: A nicotine lozenge provided herein includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and nicotine or a derivative thereof dispersed in the soluble-fiber matrix. In some cases, a nicotine lozenge provided herein includes at least 40 weight percent of soluble fiber. In some cases, soluble fiber in a nicotine lozenge provided herein can include maltodextrin. The nicotine lozenge is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity of an adult consumer and exposed to saliva. A method of making nicotine lozenges provided herein includes forming a molten mixture of at least 40 weight percent soluble fiber, nicotine, and less than 15 weight percent water while maintaining a mixture temperature of less than 150° C. and portioning the molten mixture into a plurality of nicotine lozenges. In some cases, the ingredients can be mixed to form the molten mixture in an extruder.

公开(公告)号：US09854831B2

公开(公告)日：2018-01-02

申请号：US13744930

申请日：2013-01-18

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Frank Scott Atchley ,  Gregory Griscik ,  Christopher Joseph DiNovi ,  Phillip M. Hulan ,  Diane Gee ,  Jason Flora ,  Shuzhong Zhuang

IPC: A24B13/00 ,  A24B15/10 ,  A61K31/465 ,  A24B15/16

CPC classification number: A24B15/10 ,  A24B13/00 ,  A24B15/16 ,  A61K31/465

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-stable polymer matrix. The oral product is adapted to release the nicotine or derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

公开(公告)号：US12167743B2

公开(公告)日：2024-12-17

申请号：US17752706

申请日：2022-05-24

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Frank Scott Atchley ,  Gregory James Griscik ,  Christopher Joseph Dinovi ,  Phillip M. Hulan ,  Diane L. Gee ,  Jason Flora ,  Shuzhong Zhuang

IPC: A24B15/00 ,  A24B13/00 ,  A24B15/10 ,  A24B15/16 ,  A61K31/465

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-stable polymer matrix. The oral product is adapted to release the nicotine or derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

公开(公告)号：US12133848B2

公开(公告)日：2024-11-05

申请号：US18061680

申请日：2022-12-05

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Frank Scott Atchley ,  Gregory James Griscik ,  Christopher Joseph Dinovi ,  Phillip M. Hulan ,  Diane L. Gee ,  Jason Flora ,  Shuzhong Zhuang

IPC: A24B13/00 ,  A24B15/14 ,  A24B15/16 ,  A24B15/30 ,  A61J3/10 ,  A61K9/00 ,  A61K9/20 ,  A61K31/465 ,  A61K36/81 ,  A61K45/06 ,  B29C48/00 ,  B29K75/00 ,  B29K401/00 ,  B29K407/00 ,  B29L31/00

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and a mouth-soluble binder dispersed in the mouth-stable polymer matrix.

公开(公告)号：US12109313B2

公开(公告)日：2024-10-08

申请号：US18066730

申请日：2022-12-15

Applicant: Altria Client Services LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Shuzhong Zhuang ,  Phillip M. Hulan ,  William J. Burke ,  Gerd Kobal

IPC: A61K9/20 ,  A23G3/34 ,  A23G3/38 ,  A23G3/42 ,  A61K8/73 ,  A61K9/00 ,  A61Q11/00

CPC classification number: A61K9/2059 ,  A23G3/0021 ,  A23G3/38 ,  A23G3/42 ,  A61K8/732 ,  A61Q11/00 ,  A23V2002/00 ,  A61K9/0056 ,  A23V2002/00 ,  A23V2250/5114 ,  A23V2300/16

Abstract: A soluble fiber lozenge in includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and one or more additives in the soluble-fiber matrix. A soluble fiber lozenge provided herein includes at least 40 weight percent of soluble fiber. Soluble fiber in soluble fiber lozenge can include maltodextrin. The soluble fiber lozenge is adapted to release one or more additives from the body when the body is received within the oral cavity of a consumer and exposed to saliva. A method of making soluble fiber lozenges includes forming a molten mixture of at least 40 weight percent soluble fiber, one or more additives, and less than 15 weight percent water while maintaining a mixture temperature of less than 200° C. and portioning the molten mixture into a plurality of soluble fiber lozenges.

公开(公告)号：US11779045B2

公开(公告)日：2023-10-10

申请号：US14505939

申请日：2014-10-03

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Feng Gao ,  Diane L. Gee ,  Shuzhong Zhuang ,  Phillip M. Hulan ,  William J. Burke

IPC: A24B13/00 ,  A24B15/16

CPC classification number: A24B13/00 ,  A24B15/16

Abstract: A exhausted-tobacco tablet that includes a solid solution of soluble fiber and one or more sugar alcohols, the solid solution having a glass transition temperature of less than 40° C., and exhausted-tobacco is dispersed in the solid solution, and one or more additives dispersed in the solid solution such that at least one additive is released from the tablet when the tablet is chewed or dissolved within an adult tobacco consumer's oral cavity.