Curable urethane resin composition comprising a mixture of
polyisocyanate, active hydrogen compound and diketo compound
    1.
    发明授权
    Curable urethane resin composition comprising a mixture of polyisocyanate, active hydrogen compound and diketo compound 失效
    包含多异氰酸酯,活性氢化合物和二酮化合物的混合物的可固化聚氨酯树脂组合物

    公开(公告)号:US3972846A

    公开(公告)日:1976-08-03

    申请号:US519213

    申请日:1974-10-30

    摘要: The present invention provides for a curable polyurethane composition comprising a keto compound and a liquid mixture of an organic aliphatic polyfunctional polyisocyanate and a compound having active hydrogen, the keto compound having the general formula: ##EQU1## wherein R.sub.1 and R.sub.2 are each an alkyl group, an aromatic group, and a heterocyclic group, which may be the same or different, and R.sub.2 is a lower alkylene or alkenyl group having 1 to 2 carbon atoms. The curable polyurethane composition is characterized by exhibiting a long pot life due to the existence of the aforementioned keto compound therein.

    摘要翻译: 本发明提供了一种可固化的聚氨酯组合物,其包含酮化合物和有机脂肪族多官能多异氰酸酯与具有活性氢的化合物的液体混合物,所述酮化合物具有以下通式:R1-C-R2-C-R3并行性平行O 其中R 1和R 2各自为可以相同或不同的烷基,芳族基团和杂环基,并且R 2为具有1至2个碳原子的低级亚烷基或链烯基。 可固化的聚氨酯组合物的特征在于由于其中存在上述酮化合物而表现出长的适用期。

    Method for producing non-human animal having spinal cord injury
    4.
    发明授权
    Method for producing non-human animal having spinal cord injury 失效
    生产具有脊髓损伤的非人类动物的方法

    公开(公告)号:US5993779A

    公开(公告)日:1999-11-30

    申请号:US919367

    申请日:1997-08-28

    申请人: Atsuo Mori

    发明人: Atsuo Mori

    CPC分类号: A61K49/0008

    摘要: A method for producing a non-human animal suffering from a spinal cord injury, which comprises interrupting an aorta at least at two sites, thereby forming an isolated segment of the aorta including branched parts of radicular arteries feeding the spinal cord between the sites of interruption, bringing the spinal cord to ischemia, and regionally administering glutamic acid or aspartic acid to the segment and a method for evaluating a medicament for treating a spinal cord injury due to glutamic acid or aspartic acid, which comprises interrupting an aorta of a non-human animal at least at two sites, thereby forming an isolated segment of the aorta including branched parts of redicular arteries feeding the spinal cord between the sites of interruption, bringing the spinal cord to ischemia, and regionally administering glutamic acid or aspartic acid together with a medicament for treating a spinal cord injury to the segment or a method for evaluating a medicament for treating a spinal cord injury due to glutamic acid or aspartic acid, which comprises administering a medicament for treating a spinal cord injury to a non-human animal produced according to the above method.

    摘要翻译: 一种用于产生患有脊髓损伤的非人类动物的方法,其包括至少在两个部位中断主动脉,从而形成主动脉的分离部分,其包括在中断部位之间供给脊髓的根部动脉的分支部分 ,将脊髓引导至局部缺血,并且对该片段进行谷氨酸或天冬氨酸的局部施用和用于评估由于谷氨酸或天冬氨酸引起的脊髓损伤的药物的方法,其包括中断非人类的主动脉 动物至少在两个部位,从而形成主动脉的分离的部分,包括在中断部位之间供给脊髓的支链部分的支链部分,使脊髓发生局部缺血,并与药物一起区域性施用谷氨酸或天冬氨酸 用于治疗该段的脊髓损伤或用于评估用于治疗脊髓的药物的方法 由于谷氨酸或天冬氨酸引起的损伤,其包括给予根据上述方法制备的用于治疗对非人动物的脊髓损伤的药物。

    Catheter for topical cooling and topical cooling device using the same
    5.
    发明授权
    Catheter for topical cooling and topical cooling device using the same 有权
    用于局部冷却的导管和使用其的局部冷却装置

    公开(公告)号:US08303637B2

    公开(公告)日:2012-11-06

    申请号:US12167846

    申请日:2008-07-03

    申请人: Atsuo Mori

    发明人: Atsuo Mori

    IPC分类号: A61F7/12

    摘要: Topical cooling of spinal cord, brain, esophagus, etc. can be selectively and continuously carried out under convenient control without causing any changes in internal pressure of spinal cord cavity, brain pressure, etc. by inserting a catheter, which has no hole connecting to the outside and in which a heat- cooling medium is circulated in its inner space to thereby cool a topical site; into the spinal cord, the epidural cavity, the subdural cavity or the subarachnoid cavity of the brain or the esophageal cavity and placing therein and then circulating the heat/cooling medium within the inner space of the catheter.

    摘要翻译: 脊髓,脑,食道等的局部冷却可以在方便的控制下选择性和连续地进行,而不会通过插入没有孔连接到的导管而引起脊髓腔内压,脑压等的任何变化 外部并且其内部空间中的散热介质循环,从而冷却局部位置; 进入脊髓,硬膜外腔,大脑或食管腔的硬膜下腔或蛛网膜下腔,并放置在其中,然后使热/冷介质在导管的内部空间内循环。

    Catheter for topical cooling and topical cooling device using the same
    6.
    发明申请
    Catheter for topical cooling and topical cooling device using the same 审中-公开
    用于局部冷却的导管和使用其的局部冷却装置

    公开(公告)号:US20050222652A1

    公开(公告)日:2005-10-06

    申请号:US10518370

    申请日:2003-06-16

    申请人: Atsuo Mori

    发明人: Atsuo Mori

    IPC分类号: A61F7/12 A61F7/00

    摘要: Topical cooling of spinal cord, brain, esophagus, etc. can be selectively and continuously carried out under convenient control without causing any changes in internal pressure of spinal cord cavity, brain pressure, etc. by inserting a catheter, which has no hole connecting to the outside and in which a heat-cooling medium is circulated in its inner space to thereby cool a topical site; into the spinal cord, the epidural cavity, the subdural cavity or the subarachnoid cavity of the brain or the esophageal cavity and placing therein and then circulating the heat/cooling medium within the inner space of the catheter; or using a device composed of a heat absorption member in the form of a catheter, a heat insulation member and a heat radiation member, inserting the heat absorption member in the form of a catheter into the spinal cord, the epidural cavity, the subdural cavity or the subarachnoid cavity of the brain or the esophageal cavity and placing therein and then absorbing heat from the heat absorption member and radiating the heat from the heat radiation member via the heat insulation member, thereby contributing to the treatment of spinal diseases including prevention of paraplegia accompanying thoracic aortic aneurysm surgery and the treatment of brain injury, esophageal injury and so on.

    摘要翻译: 脊髓,脑,食道等的局部冷却可以在方便的控制下选择性和连续地进行,而不会通过插入没有孔连接到的导管而引起脊髓腔内压,脑压等的任何变化 外部并且其内部空间中散热介质循环,从而冷却局部位置; 进入脊髓,硬膜外腔,大脑或食管腔的硬膜下腔或蛛网膜下腔,并放置在其中,然后使热/冷介质在导管的内部空间内循环; 或使用由导管,隔热构件和散热构件形式的吸热构件构成的装置,将导管形式的吸热构件插入脊髓,硬膜外腔,硬膜下腔 或脑或食道腔的蛛网膜下腔,并放置在其中,然后从吸热构件吸收热量,并且经由隔热构件辐射来自散热构件的热量,从而有助于治疗脊柱疾病,包括预防截瘫 伴随胸主动脉瘤手术治疗脑损伤,食管损伤等。

    Sand mold composition for metal casting
    7.
    发明授权
    Sand mold composition for metal casting 失效
    用于金属铸造的砂模组合物

    公开(公告)号:US4080213A

    公开(公告)日:1978-03-21

    申请号:US674237

    申请日:1976-04-06

    IPC分类号: B22C1/26 B22C1/22 B28B7/34

    CPC分类号: B22C1/2293

    摘要: A sand mold composition for the metal casting comprising a molding sand and pullulan as a binder therefor. As compared with prior art, the present composition has following advantages: in the molding step, no gas, dust, noise, or vibration is generated; in the pouring and sand stripping steps, neither noxious gas nor offensive odor is emitted; although the mold has a sufficiently high strength at room temperature for the convenient handling, it is readily broken down after the casting and so renders the knock-out and sand stripping very easy; and the recovered sand can be reused as such, practically without any after-treatment. The molding cycle is comparable to that of conventional oil sand or carbon dioxide-bonded mold.

    摘要翻译: 一种用于金属铸件的砂模组合物,其包含作为其粘合剂的型砂和支链淀粉。 与现有技术相比,本发明的组合物具有以下优点:在成型步骤中,不产生气体,灰尘,噪声或振动; 在倾倒和脱砂步骤中,不会排放有毒气体和异味; 虽然模具在室温下具有足够高的强度以方便处理,但是在铸造之后容易分解,从而使得脱模和脱砂非常容易; 回收的砂可以这样重复使用,实际上没有任何后处理。 成型周期与常规油砂或二氧化碳粘合模具相当。