公开(公告)号：US20230183171A1

公开(公告)日：2023-06-15

申请号：US17925873

申请日：2021-05-20

Applicant: BASF SE

Inventor： Florian Vogt ,  Kailaskumar Borate ,  Bernd Wolf ,  Joachim Gebhardt ,  Guillaume Michel Jacques Garivet ,  Harish Shinde ,  Roland Goetz

IPC: C07C259/18 ,  C12P13/00 ,  C07D271/06

CPC classification number: C07C259/18 ,  C12P13/002 ,  C07D271/06

Abstract: The present invention relates to a process for the preparation of substituted 4-(N′-hydroxy-carbamimidoyl)benzoic acids, which can be obtained by nitrilase catalyzed hydration of substituted terephthalonitriles of formula (II) in an aqueous medium to afford (ammonium) 4-cyanobenzoic acids (IIa). The hydration is followed by treatment of the aqueous reaction medium with hydroxylamine or a salt thereof to afford amidoximes (I).

公开(公告)号：US20230127884A1

公开(公告)日：2023-04-27

申请号：US17918137

申请日：2021-04-12

Applicant: BASF SE

Inventor： Florian Vogt ,  Joachim Gebhardt ,  Kailaskumar Borate ,  Bernd Wolf ,  Heinz Friedrich Sutoris ,  Roland Goetz

IPC: C07C253/30 ,  C07D271/06

Abstract: The present invention relates to a process for the preparation of 4-cyanobenzoyl chlorides of formula I through reaction of compounds of formula II with a chlorinating agent.

公开(公告)号：US09546130B2

公开(公告)日：2017-01-17

申请号：US14902890

申请日：2014-06-04

Applicant: BASF SE

Inventor： Timo Frassetto ,  Volker Maywald ,  Michael Rack ,  Maximilian Dochnahl ,  Bernd Wolf

IPC: C07C231/02 ,  C07C51/58 ,  C07C231/00

CPC classification number: C07C231/02 ,  C07C51/58 ,  C07C231/00 ,  C07C233/05 ,  C07C53/48

Abstract: The present invention relates to a process for manufacturing haloacetamides of formula (I), comprising sub-step (a): reacting halones of formula (II) with oleum; followed by sub-step (b): reacting the reaction mixture obtained in sub-step (a) with an amine of formula (IV) optionally in the presence of a base; wherein the variables are defined according to the description.

Abstract translation: 本发明涉及一种制备式（I）的卤代乙酰胺的方法，其包括以下步骤（a）：使式（II）的卤酮与发烟硫酸反应; 然后是亚步骤（b）：使在步骤（a）中获得的反应混合物与式（IV）的胺任选地在碱的存在下反应; 其中根据描述定义变量。

公开(公告)号：US20150218140A1

公开(公告)日：2015-08-06

申请号：US14421351

申请日：2013-08-09

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Goetz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07D413/04

CPC classification number: C07D413/04 ,  C07C335/28 ,  C07D265/36

Abstract: The present invention relates to a process for manufacturing benzoxazinones of formula (I), wherein the variables are defined according to the description, by reacting carbamates of formula (II) are reacted with carbamat-benzoxazinones of formula (III) in the presence of a base.

Abstract translation: 本发明涉及一种制备式（I）的苯并恶嗪酮的方法，其中根据描述定义变量，使式（II）的氨基甲酸酯与式（III）的氨基甲酸酯 - 苯并恶嗪酮反应，在 基础。

公开(公告)号：US08592578B2

公开(公告)日：2013-11-26

申请号：US13653615

申请日：2012-10-17

Applicant: BASF SE

Inventor： Thomas Zierke ,  Volker Maywald ,  Michael Rack ,  Sebastian Peer Smidt ,  Michael Keil ,  Bernd Wolf ,  Christopher Koradin

IPC: C07D231/14 ,  C07D265/30 ,  C07D295/145

CPC classification number: C07D231/14 ,  C07C229/30 ,  C07D295/145

Abstract: The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters, 2-(aminomethylidene)-4,4-difluoro-3-oxobutteric esters of the formula (I) in which R1, R2 and R3 independently of one another are C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C10-cycloalkyl or benzyl or NR2R3 is a 5- to 10-membered heterocyclic radical, to a process for preparing compounds of the formula (I) wherein an appropriate 3-aminoacrylic ester is reacted with difluoroacetyl fluoride and to the use of compounds of the formula (I) in the process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters.

Abstract translation: 本发明涉及式（I）的二氟甲基取代的吡唑-4-基羧酸及其酯，2-（氨基亚甲基）-4,4-二氟-3-氧代苦味酯的方法，其中R 1，R 2和 R 3彼此独立地是C 1 -C 6 - 烷基，C 1 -C 6 - 卤代烷基，C 2 -C 6 - 烯基，C 3 -C 10 - 环烷基或苄基或NR 2 R 3是5-至10-元杂环基， 式（I）的化合物，其中适当的3-氨基丙烯酸酯与二氟乙酰氟反应，以及在制备二氟甲基取代的吡唑-4-基羧酸及其酯的方法中使用式（I）的化合物。

公开(公告)号：US20230066401A1

公开(公告)日：2023-03-02

申请号：US17795941

申请日：2021-02-01

Applicant: BASF SE

Inventor： Florian Vogt ,  Kailaskumar Borate ,  Bernd Wolf ,  Christopher Koradin ,  Roland Goetz ,  Harish Shinde

IPC: C07D271/06

Abstract: The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles of formula (I), which can be obtained through reaction of amidoxime compounds of formula (II) with a haloacetic ester in the presence of a base.

公开(公告)号：US09353095B2

公开(公告)日：2016-05-31

申请号：US14402518

申请日：2013-05-15

Applicant: BASF SE

Inventor： Robert Reinhard ,  Tiziana Chiodo ,  Bernd Wolf ,  Stefan Scherer ,  Matthias Bratz ,  Matthias Witschel ,  Trevor William Newton ,  Thomas Seitz

IPC: A01N43/84 ,  C07D413/04

CPC classification number: C07D413/04 ,  A01N43/84 ,  C07B2200/13 ,  A01N25/12 ,  A01N2300/00

Abstract: The present invention relates to a novel crystalline form A of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione. The invention also relates to a process for the production of this crystalline form and formulations for plant protection which contains the novel crystalline form of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione.

Abstract translation: 本发明涉及1,5-二甲基-6-硫代-3-（2,2,7-三氟-3-氧代-4-（丙-2-炔基）-3,4-二氢 - -2,3-二氢-2H-苯并[b] [1,4]恶嗪-6-基）-1,3,5-三氮杂环戊烷-2,4-二酮。 本发明还涉及生产该结晶形式的方法和用于植物保护的制剂，其含有1,5-二甲基-6-硫代-3-（2,2,7-三氟-3-氧代 -4-（丙-2-炔基）-3,4-二氢-2H-苯并[b] [1,4]恶嗪-6-基）-1,3,5-三氮杂环戊烷-2,4-二酮。

公开(公告)号：US09353070B2

公开(公告)日：2016-05-31

申请号：US14421348

申请日：2013-08-07

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Goetz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07D265/36 ,  C07D413/04

CPC classification number: C07D265/36 ,  C07D413/04

Abstract: The present invention relates to carbamat-benzoxazinones of formula (I), wherein the variables are defined according to the description, as well as to a process for manufacturing carbamat-benzoxazinones of formula (I), and to the use of carbamat-benzoxazinones of formula (I) in manufacturing benzoxazinones of formula (X).

Abstract translation: 本发明涉及式（I）的氨基甲酰 - 苯并恶嗪酮，其中根据描述定义变量，以及制备式（I）的氨基甲酰 - 苯并恶嗪酮的方法，以及使用式（I）的氨基甲酰 - 苯并恶嗪酮 式（I）在制备式（X）的苯并恶嗪酮时。

公开(公告)号：US20150218139A1

公开(公告)日：2015-08-06

申请号：US14421321

申请日：2013-07-29

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Götz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07D413/04 ,  C07D265/36 ,  C07C335/28

CPC classification number: C07D413/04 ,  C07C275/60 ,  C07C335/28 ,  C07D265/36

Abstract: The present invention relates to carbamates of formula (I), wherein the variables are defined according to the description, as well as to a process for manufacturing carbamates of formula (I), and to the use of carbamates of formula (I) in manufacturing benzoxazinones of formula (VII).

Abstract translation: 本发明涉及式（I）的氨基甲酸酯，其中根据描述定义变量，以及制备式（I）的氨基甲酸酯的方法，以及式（I）的氨基甲酸酯在制造中的用途 式（VII）的苯并恶嗪酮。

公开(公告)号：US09518045B2

公开(公告)日：2016-12-13

申请号：US14421351

申请日：2013-08-09

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Goetz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07D413/04 ,  C07D265/36 ,  C07C335/28

CPC classification number: C07D413/04 ,  C07C335/28 ,  C07D265/36

Abstract: The present invention relates to a process for manufacturing benzoxazinones of formula (I), wherein the variables are defined according to the description, by reacting carbamates of formula (II) are reacted with carbamat-benzoxazinones of formula (III) in the presence of a base.