公开(公告)号：US11014863B2

公开(公告)日：2021-05-25

申请号：US16613307

申请日：2018-05-14

Applicant: BASF SE

Inventor： Stephan Zuend ,  Rainer Papp ,  Boris Breitscheidel ,  Armin Lange De Oliveira

IPC: C07C29/00 ,  B01J23/00 ,  C07C29/149 ,  B01J23/72 ,  C07C31/12

Abstract: A process for preparing C4 to C13 monohydroxy compounds from a bottom fraction arising in the distillation of a crude mixture of C4 to C13 oxo-process aldehydes from cobalt-catalyzed or rhodium-catalyzed hydroformylation, or in the distillation of a crude mixture of C4 to C13 oxo-process alcohols, which comprises contacting the bottom fraction in the presence of hydrogen with a catalyst comprising copper oxide and aluminum oxide, at a temperature of 150° C. to 300° C. and a pressure of 20 bar to 300 bar and subjecting the resulting crude hydrogenation product to distillation, and the amount of C4 to C13 monohydroxy compounds present in the crude hydrogenation product after the hydrogenation being greater than the amount of C4 to C13 monohydroxy compounds given stoichiometrically from the hydrogenation of the ester and aldehyde compounds present in the bottom fraction, including the C4 to C13 monohydroxy compounds still present in the bottom fraction before the hydrogenation.

公开(公告)号：US11407700B2

公开(公告)日：2022-08-09

申请号：US16307197

申请日：2017-06-06

Applicant: BASF SE

Inventor： Stephan Zuend ,  Andreas Keller ,  Gabriele Gralla ,  Wolfgang Krause

IPC: C07C29/141 ,  B01J23/89 ,  B01J37/00 ,  B01J37/02 ,  B01J37/04 ,  B01J37/06 ,  C11B9/00

Abstract: The present invention provides a process for preparing an unsaturated alcohol of the formula (I), wherein one of R1 and R2 is preferably C2-C10-alkyl or C2-C10-alkenyl containing one double bond and the other one is preferably hydrogen or methyl; R3 is preferably hydrogen; which comprises subjecting an educt composition including at least 75% by weight of an unsaturated aldehyde of the formula (II) wherein R1, R2 and R3 preferably have the above defined meanings, to a hydrogenation in the presence of a catalyst and a tertiary amine; wherein the tertiary amine is used in an amount ranging from 0.001 to 0.7% by weight, based on the total amount of the liquid reaction mixture. The invention further relates to the nerol compound obtainable by the inventive process, to a fragrance or aroma substance composition comprising the nerol compound obtainable by the inventive process, to a method for imparting and/or intensifying an odor or flavor of a product, and also to perfumed or aromatized products comprising a nerol compound obtainable by the inventive process.

公开(公告)号：US11512040B2

公开(公告)日：2022-11-29

申请号：US17257080

申请日：2019-07-02

Applicant: BASF SE ,  BASF CORPORATION ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Martin Ernst ,  Stephan Zuend ,  Bo Su ,  Ala Bunescu ,  John F. Hartwig

IPC: C07C213/00

Abstract: A process for the preparation of amino alcohols includes condensing a compound of Formula (II), a stereoisomer, a tautomer, or a salt thereof with a compound of Formula (IIIa) or Formula (IIIb), a stereoisomer, a tautomer, or a salt thereof to form a condensation product; hydroxylating or acyloxylating the condensation product in the presence of an oxidant to obtain a hydroxylation or acyloxylation product; and subjecting the hydroxylation or acyloxylation product to one or more subsequent reactions comprising a hydrolysis reaction, alcohol deprotection, an amino lysis reaction, or a combination of two or more thereof to obtain an amino alcohol of Formula (I).