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公开(公告)号：US09758487B2
公开(公告)日：2017-09-12
申请号：US15194980
申请日：2016-06-28
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K38/20 , A61K31/4164 , A61K31/517 , A61K31/715 , A61K38/46 , A61P31/00 , C07D403/02 , C07D401/00 , C07D233/64 , C07D401/14 , C07D403/14 , A61K31/4178 , A61K45/06 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09227961B2
公开(公告)日：2016-01-05
申请号：US14488990
申请日：2014-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D401/14 , C07D403/14 , C07D413/14 , C07D233/64 , C07D405/14 , A61K31/4178 , A61K45/06
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20130034520A1
公开(公告)日：2013-02-07
申请号：US13650374
申请日：2012-10-12
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K31/4178 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D401/14 , A61P31/14 , A61K38/05 , A61K38/21 , A61K31/7056 , A61K38/20 , A61K31/713 , C07D403/14 , A61K31/454
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20150210684A1
公开(公告)日：2015-07-30
申请号：US14419559
申请日：2013-08-07
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Tao Wang , Zhongxing Zhang , John F. Kadow , Nicholas A. Meanwell , Edward H. Ruediger , Clint A. James , Daniel H. Deon , David J. Carini , Barry L. Johnson
IPC: C07D471/04 , A61K45/06 , A61K31/4545 , C07D401/06 , A61K31/454
CPC classification number: C07D471/04 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D401/06
Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof: formule (I): wherein A is selected from the group consisting of: formule (II) and wherein Z is selected from the group consisting of: formule (III): and. are useful as HIV attachment inhibitors.
Abstract translation: 式I化合物，包括其药学上可接受的盐：式（I）：其中A选自：结构（II），并且其中Z选自：基团（III）：和。 可用作HIV附着抑制剂。
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公开(公告)号：US08642025B2
公开(公告)日：2014-02-04
申请号：US13650374
申请日：2012-10-12
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: A61K31/454 , A61K31/713 , A61K31/4178 , A61K31/5377 , A61K31/496 , A61K31/7056 , A61K38/05 , A61K38/21 , A61K38/20 , A61P31/14 , C07D413/14 , C07D401/14 , C07D403/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Abstract translation: 本公开涉及用于治疗丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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Patent Agency Ranking
公开(公告)号：US20130280211A1
公开(公告)日：2013-10-24
申请号：US13919027
申请日：2013-06-17
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. ST. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D403/14 , C07D401/14 , A61K45/06 , A61K31/5377 , C07F7/10 , A61K31/695 , A61K31/4178 , A61K31/4545
CPC classification number: C07D403/14 , A61K31/4178 , A61K31/4545 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07F7/10
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09505752B2
公开(公告)日：2016-11-29
申请号：US14419559
申请日：2013-08-07
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Tao Wang , Zhongxing Zhang , John F. Kadow , Nicholas A. Meanwell , Edward H. Ruediger , Clint A. James , Daniel H. Deon , David J. Carini , Barry L. Johnson
IPC: C07D471/04 , A61K31/4545 , C07D401/06 , A61K31/454 , A61K45/06
CPC classification number: C07D471/04 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D401/06
Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof: formula (I): wherein A is selected from the group consisting of: formula (II) and wherein Z is selected from the group consisting of: formula (III): and. are useful as HIV attachment inhibitors.
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公开(公告)号：US08846023B2
公开(公告)日：2014-09-30
申请号：US14021686
申请日：2013-09-09
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: C07D403/14 , C07D405/14 , C07D417/14 , A61K31/506 , A61K31/4178 , A61K31/427 , A61K31/13 , A61K31/7105 , A61K31/4745 , A61K31/7056 , A61K38/20 , A61K38/21 , C07D401/14
CPC classification number: A61K31/506 , A61K31/13 , A61K31/4178 , A61K31/427 , A61K31/4745 , A61K31/7056 , A61K31/7105 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20160311778A1
公开(公告)日：2016-10-27
申请号：US15194980
申请日：2016-06-28
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: C07D233/64 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14 , C07D403/14 , C07D401/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20150190387A1
公开(公告)日：2015-07-09
申请号：US14419564
申请日：2013-08-07
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Tao Wang , John F. Kadow , Nicholas A. Meanwell , Zhongxing Zhang , Zhiwei Yin , Edward H. Ruediger , Clint A. James , Daniel H. Deon
IPC: A61K31/4545 , C07D401/14 , C07D401/06 , A61K31/454 , C07D471/04 , A61K45/06
CPC classification number: A61K31/4545 , A61K31/454 , A61K45/06 , C07D401/06 , C07D401/14 , C07D471/04
Abstract: Compounds of Formula (I), including pharmaceutically acceptable salts thereof: wherein A is selected from the group consisting of: and wherein Z is: are useful as HIV attachment inhibitors.
Abstract translation: 式（I）的化合物，包括其药学上可接受的盐：其中A选自：并且其中Z是：可用作HIV附着抑制剂。
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