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公开(公告)号：US09856292B2
公开(公告)日：2018-01-02
申请号：US14938327
申请日：2015-11-11
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Kevin W. Gillman , Jason Goodrich , Kenneth M. Boy , Yunhui Zhang , Claudio Mapelli , Michael A. Poss , Paul Michael Scola , David R. Langley , Nicholas A. Meanwell
CPC classification number: C07K7/08 , A61K38/00 , A61K38/10 , A61K45/06 , A61K51/088 , C07K7/56 , Y02A50/463
Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
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公开(公告)号：US09758487B2
公开(公告)日：2017-09-12
申请号：US15194980
申请日：2016-06-28
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K38/20 , A61K31/4164 , A61K31/517 , A61K31/715 , A61K38/46 , A61P31/00 , C07D403/02 , C07D401/00 , C07D233/64 , C07D401/14 , C07D403/14 , A61K31/4178 , A61K45/06 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US11066445B2
公开(公告)日：2021-07-20
申请号：US16624989
申请日：2018-06-21
Applicant: Bristol-Myers Squibb Company
Inventor： Kevin W. Gillman , Jason Goodrich , Li-Qiang Sun , Eric Mull , David R. Langley , Paul Michael Scola
Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
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公开(公告)号：US10988507B2
公开(公告)日：2021-04-27
申请号：US16462508
申请日：2017-11-06
Applicant: Bristol-Myers Squibb Company
Inventor： Kevin W. Gillman , Jason Goodrich , David R. Langley , Paul Michael Scola
Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
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公开(公告)号：US09227961B2
公开(公告)日：2016-01-05
申请号：US14488990
申请日：2014-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D401/14 , C07D403/14 , C07D413/14 , C07D233/64 , C07D405/14 , A61K31/4178 , A61K45/06
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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Patent Agency Ranking
公开(公告)号：US08735398B2
公开(公告)日：2014-05-27
申请号：US13670691
申请日：2012-11-07
Applicant: Bristol-Myers Squibb Company
Inventor： Omar D. Lopez , Denis R. St. Laurent , Jason Goodrich , Jeffrey Lee Romine , Michael Serrano-Wu , Fukang Yang , Ramesh Kakarla , Xuejie Yang , Yuping Qiu , Lawrence B. Snyder
IPC: C07D249/08 , C07D231/12 , C07D413/14 , C07D233/58 , A61K31/4196 , A61K31/4245 , A61K31/415
CPC classification number: A61K31/415 , A61K31/4196 , A61K31/4245 , C07D231/12 , C07D233/58 , C07D233/64 , C07D249/06 , C07D249/08 , C07D249/12 , C07D263/32 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein.
Abstract translation: 本公开一般涉及抗病毒化合物，更具体地涉及可以抑制由丙型肝炎病毒（HCV）编码的NS5A蛋白的功能的化合物，包含这些化合物的组合物，以及用于抑制NS5A蛋白功能的方法。
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公开(公告)号：US20130085147A1
公开(公告)日：2013-04-04
申请号：US13670691
申请日：2012-11-07
Applicant: Bristol-Myers Squibb Company
Inventor： Omar D. Lopez , Denis R. St. Laurent , Jason Goodrich , Jeffrey Lee Romine , Michael Serrano-Wu , Fukang Yang , Ramesh Kakarla , Xuejie Yang , Yuping Qiu , Lawrence B. Snyder
IPC: C07D471/04 , C07D249/12 , C07D417/14 , C07D403/14 , C07D263/32 , C07D413/14
CPC classification number: A61K31/415 , A61K31/4196 , A61K31/4245 , C07D231/12 , C07D233/58 , C07D233/64 , C07D249/06 , C07D249/08 , C07D249/12 , C07D263/32 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein.
Abstract translation: 本公开一般涉及抗病毒化合物，更具体地涉及可以抑制由丙型肝炎病毒（HCV）编码的NS5A蛋白的功能的化合物，包含这些化合物的组合物，以及用于抑制NS5A蛋白功能的方法。
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公开(公告)号：US20130034520A1
公开(公告)日：2013-02-07
申请号：US13650374
申请日：2012-10-12
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K31/4178 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D401/14 , A61P31/14 , A61K38/05 , A61K38/21 , A61K31/7056 , A61K38/20 , A61K31/713 , C07D403/14 , A61K31/454
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20180086793A1
公开(公告)日：2018-03-29
申请号：US15822744
申请日：2017-11-27
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Kevin W. Gillman , Jason Goodrich , Kenneth M. Boy , Yunhui Zhang , Claudio Mapelli , Michael A. Poss , Paul Michael Scola , David R. Langley , Nicholas A. Meanwell
CPC classification number: C07K7/08 , A61K38/00 , A61K38/10 , A61K45/06 , A61K51/088 , C07K7/56 , Y02A50/463
Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
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公开(公告)号：US20160137696A1
公开(公告)日：2016-05-19
申请号：US14938327
申请日：2015-11-11
Applicant: Bristol-Myers Squibb Company
Inventor： Kevin W. Gillman , Jason Goodrich , Kenneth M. Boy , Yunhui Zhang , Claudio Mapelli , Michael A. Poss , Li-Qiang Sun , Qian Zhao , Eric Mull , Eric P. Gillis , Paul Michael Scola
CPC classification number: C07K7/08 , A61K38/00 , A61K38/10 , A61K45/06 , A61K51/088 , C07K7/56 , Y02A50/463
Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
Abstract translation: 本公开提供了作为免疫调节剂的化合物，因此可用于改善各种疾病，包括癌症和感染性疾病。
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