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    Use of benzotriazole derivatives for photostabilisation
    2.
    发明申请
    Use of benzotriazole derivatives for photostabilisation 有权
    苯并三唑衍生物用于光稳定化

    公开(公告)号：US20100008873A1

    公开(公告)日：2010-01-14

    申请号：US11919104

    申请日：2006-04-20

    申请人： Stefan Müller ,  Jochen Giesinger ,  Thomas Ehlis ,  Bernd Herzog ,  Peter König ,  Gilbert Kreyer ,  Katja Quass

    发明人： Stefan Müller ,  Jochen Giesinger ,  Thomas Ehlis ,  Bernd Herzog ,  Peter König ,  Gilbert Kreyer ,  Katja Quass

    IPC分类号： A61K8/49 ,  A61P17/04

    CPC分类号： A61Q17/04 ,  A61K8/496 ,  A61K2800/52

    摘要： Use of benzotriazole derivatives of formula (1), wherein R1 is C1-C30alkyl; C1C5alkoxy; C1-C5alkoxycarbonyl; C5-C7cycloalkyl; C6-C10aryl; aralkyl; —SO3M; a radical of formula (1a) R3 is hydrogen; C1C5alkyl; C1C5alkoxy; halogen, preferably Cl; or hydroxy; R4 and R5 are each independently of the other hydrogen; or d-C5alkyl; m is 1 or 2; n is O or 1; if m=1, R2 is hydrogen; unsubstituted or phenyl-substituted d-C1-C12alkyl; or C6-C10aryl; if m=2, R2 is the direct bond; or —(CH2)p—; and p is 1 to 3; for enhancing the photostability of cosmetic or dermatologic compositions comprising at least one further organic UV absorber.

    摘要翻译： 式（1）的苯并三唑衍生物的用途，其中R 1是C 1 -C 30烷基; C1C5烷氧基 C1-C5烷氧基羰基; C5-C7环烷基; C6-C10芳基; 芳烷基 -SO3M; 式（1a）的基团R 3是氢; C 1 -C 5烷基; C1C5烷氧基 卤素，优选Cl; 或羟基; R4和R5各自独立地为氢; 或d-C 5烷基; m为1或2; n为0或1; 如果m = 1，则R2为氢; 未取代或苯基取代的d-C 1 -C 12烷基; 或C 6 -C 10芳基; 如果m = 2，则R2是直接键; 或 - （CH 2）p - ; p为1〜3; 用于增强包含至少一种另外的有机UV吸收剂的化妆品或皮肤病学组合物的光稳定性。

    Merocyanine derivatives
    3.
    发明授权
    Merocyanine derivatives 有权

    公开(公告)号：US07772242B2

    公开(公告)日：2010-08-10

    申请号：US11630489

    申请日：2005-06-20

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    IPC分类号： A61K31/519 ,  A61K31/445 ,  A61K31/16 ,  A61K31/165

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of the compounds of formula  wherein Q is —OH; —OR7; —NH2; —NHR7; —NR7R8; or —N═R9; T is —COR5; —CN; or —SO2—(C6-C12)aryl; R1 is hydrogen; —OR7, —SR7; —NHR7; —NR7R8; C1-C22alkyl; C2-C12Alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R2 and R3 independently from each other are C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl, C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C2-C11heteroaralkyl, C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONH2; CONHR7; CONR7R8; SO2(C6-C12)aryl, C2-C12alk-1 -enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl, C3-C5heterocycloalkyl, C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl or C1-C9heteroaryl; R6, R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; o-C6-C10aryl; or C1-C9heteroaryl; R9 is a (C1-C6)alkylidene radical; or R1 and R2, R1 and Q, R1 and R4, R1 and R6, R2 and R3, R3 and Q, R6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocycic rings, and each N atom in a N-heterocyclic ring may be substituted by C1-C22alkyl; and n is a number from 1 to 4; for protecting of human hair and skin against the damaging effect of UV radiation.

    BENZYLIDENE MALONATES
    5.
    发明申请
    BENZYLIDENE MALONATES 审中-公开
    苯并噻唑啉酮

    公开(公告)号：US20120128745A1

    公开(公告)日：2012-05-24

    申请号：US13322628

    申请日：2010-05-19

    申请人： Markus Hansch ,  Thomas Ehlis ,  Olof Wallquist ,  Barbara Wagner ,  Bernd Herzog ,  Jochen Giesinger

    发明人： Markus Hansch ,  Thomas Ehlis ,  Olof Wallquist ,  Barbara Wagner ,  Bernd Herzog ,  Jochen Giesinger

    IPC分类号： A61K8/02 ,  C07C69/734 ,  A61K8/41 ,  A61K8/49 ,  A61K8/37 ,  A61Q17/04

    CPC分类号： A61K8/37 ,  A61Q17/04 ,  C07C69/73

    摘要： Disclosed is the use of benzylidene malonates of formula (1) wherein R1 is methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; a radical of formula (1a) or a radical of formula (1b) wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; for the protection of human and animal hair and skin against UV radiation.

    摘要翻译： 公开了使用式（1）的亚苄基丙二酸酯，其中R 1是甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基，那么R是叔丁基。 丁基; 式（1a）的基团或式（1b）的基团，其中R2和R3彼此独立地为氢; 或甲基; R4是甲基; 乙基; 或正丙基​​; R5和R6彼此独立地是氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基，那么R是异丙基; 用于保护人和动物的头发和皮肤免受紫外线辐射。

    Merocyanine derivatives
    6.
    发明授权
    Merocyanine derivatives 有权
    梅花菁衍生物

    公开(公告)号：US08044058B2

    公开(公告)日：2011-10-25

    申请号：US12715839

    申请日：2010-03-02

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    IPC分类号： A61K31/517 ,  A61K31/445 ,  A61K31/16

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.

    摘要翻译： 披露式Q的部花青衍生物的用途是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7，-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5为-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - （CH 2）t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si（OR10）（OR11）（OR12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u -O-（CH 2）v -SiR 10 R 11 R 12; 或基团X-Sil; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。

    Use of benzotriazole derivatives for photostabilisation
    7.
    发明授权
    Use of benzotriazole derivatives for photostabilisation 有权
    苯并三唑衍生物用于光稳定化

    公开(公告)号：US08361446B2

    公开(公告)日：2013-01-29

    申请号：US11919104

    申请日：2006-04-20

    申请人： Stefan Müller ,  Jochen Giesinger ,  Thomas Ehlis ,  Bernd Herzog ,  Peter König ,  Gilbert Kreyer ,  Katja Quass

    发明人： Stefan Müller ,  Jochen Giesinger ,  Thomas Ehlis ,  Bernd Herzog ,  Peter König ,  Gilbert Kreyer ,  Katja Quass

    IPC分类号： A61K8/49 ,  A61P17/04

    CPC分类号： A61Q17/04 ,  A61K8/496 ,  A61K2800/52

    摘要： Use of benzotriazole derivatives of formula (1), wherein R1 is C1-C30alkyl; C1C5alkoxy; C1-C5alkoxycarbonyl; C5-C7cycloalkyl; C6-C10aryl; aralkyl; —SO3M; a radical of formula (1a) R3 is hydrogen; C1C5alkyl; C1C5alkoxy; halogen, preferably Cl; or hydroxy; R4 and R5 are each independently of the other hydrogen; or d-C5alkyl; m is 1 or 2; n is O or 1; if m=1, R2 is hydrogen; unsubstituted or phenyl-substituted d-C1-C12alkyl; or C6-C10aryl; if m=2, R2 is the direct bond; or —(CH2)p—; and p is 1 to 3; for enhancing the photostability of cosmetic or dermatologic compositions comprising at least one further organic UV absorber.

    摘要翻译： 式（1）的苯并三唑衍生物的用途，其中R 1是C 1 -C 30烷基; C1C5烷氧基 C1-C5烷氧基羰基; C5-C7环烷基; C6-C10芳基; 芳烷基 -SO3M; 式（1a）的基团R 3是氢; C 1 -C 5烷基; C1C5烷氧基 卤素，优选Cl; 或羟基; R4和R5各自独立地为氢; 或d-C 5烷基; m为1或2; n为0或1; 如果m = 1，则R2为氢; 未取代或苯基取代的d-C 1 -C 12烷基; 或C 6 -C 10芳基; 如果m = 2，则R2是直接键; 或 - （CH 2）p - ; p为1〜3; 用于增强包含至少一种另外的有机UV吸收剂的化妆品或皮肤病学组合物的光稳定性。

    MEROCYANINE DERIVATIVES
    8.
    发明申请
    MEROCYANINE DERIVATIVES 有权
    月桂酰胺衍生物

    公开(公告)号：US20100209466A1

    公开(公告)日：2010-08-19

    申请号：US12715839

    申请日：2010-03-02

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    IPC分类号： A61K8/41 ,  A61Q17/04 ,  A61K8/49 ,  A61K8/42 ,  A61K8/46 ,  A61K8/58 ,  A61K8/898 ,  A61K8/02

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.

    摘要翻译： 公开了使用式Q的部花青衍生物是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7，-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5是-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - （CH 2）t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si（OR10）（OR11）（OR12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u -O-（CH 2）v -SiR 10 R 11 R 12; 或X-Sil基团; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。

    Merocyanine Derivatives
    9.
    发明申请
    Merocyanine Derivatives 有权

    公开(公告)号：US20090010860A1

    公开(公告)日：2009-01-08

    申请号：US11630489

    申请日：2005-06-20

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jurg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jurg Haase

    IPC分类号： A61K8/49 ,  C07D309/38 ,  A61K31/366 ,  A61K31/505 ,  C07D239/26 ,  C07D207/08 ,  A61K31/40 ,  A61Q17/04

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of the compounds of formula wherein Q is —OH; —OR7; —NH2; —NHR7; —NR7R8; or —N═R9; T is —COR5; —CN; or —SO2—(C6-C12)aryl; R1 is hydrogen; —OR7, —SR7; —NHR7; —NR7R8; C1-C22alkyl; C2-C12Alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R2 and R3 independently from each other are C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl, C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C2-C11heteroaralkyl, C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONH2; CONHR7; CONR7R8; SO2(C6-C12)aryl, C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl, C3-C5heterocycloalkyl, C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C2-C12alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C8-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C8-C10aryl or C1-C9heteroaryl; R6, R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; o-C6-C10aryl; or C1-C9heteroaryl; R9 is a (C1-C6)alkylidene radical; or R1 and R2, R1 and Q, R1 and R4, R1 and R8, R2 and R3, R3 and Q, R6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocycic rings, and each N atom in a N-heterocyclic ring may be substituted by C1-C22alkyl; and n is a number from 1 to 4; for protecting of human hair and skin against the damaging effect of UV radiation.

    Merocyanine derivatives for cosmetic use
    10.
    发明授权
    Merocyanine derivatives for cosmetic use 有权
    用于化妆品使用的花青衍生物

    公开(公告)号：US07893292B2

    公开(公告)日：2011-02-22

    申请号：US12378566

    申请日：2009-02-17

    申请人： Barbara Wagner ,  Thomas Ehlis ,  Stefan Müller

    发明人： Barbara Wagner ,  Thomas Ehlis ,  Stefan Müller

    IPC分类号： C07C255/00 ,  A61K8/00 ,  A61K8/18 ,  A61K8/49 ,  A61K31/13 ,  A61K31/16 ,  A61Q17/04 ,  A01N33/00 ,  A01N33/02

    CPC分类号： C07D295/116 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/494 ,  A61K8/81 ,  A61Q17/00 ,  A61Q17/02 ,  C07C225/20 ,  C07C229/46 ,  C07C255/31 ,  C07C317/48 ,  C07C2601/14 ,  C07C2601/16 ,  C07D295/155

    摘要： Described are merocyanine derivatives of formula wherein R2 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; a cyano group; or R1 and R2 together with the nitrogen atom linking them form a —(CH2)m— ring which is optionally interrupted by —O— or by —NR7—; R4 is a cyano group; or -Q1-R5; Q1 is —COO—; —CONH—; —CO—; —SO2—; or —CONR6—; R5 is C1-C22alkyl; cyclo-C3-C8alkyl; or unsubstituted or C1-C6alkyl-substituted C6-C20aryl; R6 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; R7 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; the cyclohexene radical C is not substituted or substituted by one or more C1-C5alkyl; m is from 3 to 7; n is from 2 to 4; and o is from 2 to 4. Said merocyanine derivatives are useful in protecting human and animal hair and skin from UV radiation and to cosmetic compositions comprising said derivatives.

    摘要翻译： 描述的是下式的部花青衍生物其中R2是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; 氰基; 或R 1和R 2与连接它们的氮原子一起形成 - （CH 2）m - 环，其任选被-O-或-NR 7 - 间隔; R4是氰基; 或-Q1-R5; Q1是-COO-; -CONH-; -CO-; -SO2-; 或-CONR6-; R5是C1-C22烷基; 环C 3 -C 8烷基; 或未取代的或C 1 -C 6烷基取代的C 6 -C 20芳基; R6是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; R7是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; 环己烯基C不被一个或多个C 1 -C 5烷基取代或取代; m为3〜7; n为2〜4; 和o为2至4.所述的部花青衍生物可用于保护人和动物毛发和皮肤免受紫外线辐射和包含所述衍生物的化妆品组合物。