公开(公告)号：US20250121372A1

公开(公告)日：2025-04-17

申请号：US18901984

申请日：2024-09-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kevin D. NESS ,  Christopher F. KELLY ,  Donald A. MASQUELIER

IPC: B01L3/00 ,  B01F23/41 ,  B01F33/3011 ,  B01L3/02 ,  B01L7/00 ,  C12Q1/6806 ,  G01N35/00 ,  G01N35/08 ,  G01N35/10

Abstract: A system, including method and apparatus, for generating droplets suitable for droplet-based assays. The disclosed systems may include either one-piece or multi-piece droplet generation components configured to form sample-containing droplets by merging aqueous, sample-containing fluid with a background emulsion fluid such as oil, to form an emulsion of sample-containing droplets suspended in the background fluid. In some cases, the disclosed systems may include channels or other suitable mechanisms configured to transport the sample-containing droplets to an outlet region, so that subsequent assay steps may be performed.

公开(公告)号：US20190247856A1

公开(公告)日：2019-08-15

申请号：US16397774

申请日：2019-04-29

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kevin D. NESS ,  Christopher F. KELLY ,  Donald A. MASQUELIER

IPC: B01L3/00 ,  B01F3/08 ,  B01F13/00 ,  G01N35/08 ,  C12Q1/6806

Abstract: A system, including method and apparatus, for generating droplets suitable for droplet-based assays. The disclosed systems may include either one-piece or multi-piece droplet generation components configured to form sample-containing droplets by merging aqueous, sample-containing fluid with a background emulsion fluid such as oil, to form an emulsion of sample-containing droplets suspended in the background fluid. In some cases, the disclosed systems may include channels or other suitable mechanisms configured to transport the sample-containing droplets to an outlet region, so that subsequent assay steps may be performed.

公开(公告)号：US20210031200A1

公开(公告)日：2021-02-04

申请号：US16995555

申请日：2020-08-17

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kevin D. NESS ,  Christopher F. KELLY ,  Donald A. MASQUELIER

IPC: B01L3/00 ,  B01F13/00 ,  B01F3/08 ,  G01N35/08 ,  C12Q1/6806

Abstract: A system, including method and apparatus, for generating droplets suitable for droplet-based assays. The disclosed systems may include either one-piece or multi-piece droplet generation components configured to form sample-containing droplets by merging aqueous, sample-containing fluid with a background emulsion fluid such as oil, to form an emulsion of sample-containing droplets suspended in the background fluid. In some cases, the disclosed systems may include channels or other suitable mechanisms configured to transport the sample-containing droplets to an outlet region, so that subsequent assay steps may be performed.

公开(公告)号：US20190046987A1

公开(公告)日：2019-02-14

申请号：US16160783

申请日：2018-10-15

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kevin D. NESS ,  Christopher F. KELLY ,  Donald A. MASQUELIER

IPC: B01L3/00 ,  B01F3/08 ,  B01F13/00 ,  C12Q1/6806 ,  G01N35/08 ,  B01L7/00 ,  B01L3/02 ,  G01N35/10 ,  G01N35/00

Abstract: A system, including method and apparatus, for generating droplets suitable for droplet-based assays. The disclosed systems may include either one-piece or multi-piece droplet generation components configured to form sample-containing droplets by merging aqueous, sample-containing fluid with a background emulsion fluid such as oil, to form an emulsion of sample-containing droplets suspended in the background fluid. In some cases, the disclosed systems may include channels or other suitable mechanisms configured to transport the sample-containing droplets to an outlet region, so that subsequent assay steps may be performed.