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公开(公告)号：US20210335023A1
公开(公告)日：2021-10-28
申请号：US16860425
申请日：2020-04-28
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yujie LU , Evren ASMA , Yi QIANG , Jeffrey KOLTHAMMER , Zhou YU
Abstract: The present disclosure relates to an apparatus for estimating scatter in positron emission tomography, comprising processing circuitry configured to acquire an emission map and an attenuation map, each representing an initial image reconstruction of a positron emission tomography scan, calculate, using a radiative transfer equation (RTE) method, a scatter source map of a subject of the positron emission tomography scan based on the emission map and the attenuation map, estimate, using the RTE method and based on the emission map, the attenuation map, and the scatter source map, scatter, and perform an iterative image reconstruction of the positron emission tomography scan based on the estimated scatter and raw data from the positron emission tomography scan of the subject.
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2.发明公开公开(公告)号：US20240225585A1
公开(公告)日：2024-07-11
申请号：US18336807
申请日：2023-06-16
Inventor： Wenyuan QI , Li YANG , Jeffrey KOLTHAMMER , Yu-Jung TSAI , Evren ASMA , Maria IATROU , Jinyi QI , Tiantian LI
Abstract: A method for performing single gating in a positron emission tomography (PET) system includes: receiving list-mode data acquired by scanning an imaging object using the PET system, the list-mode data being affected by quasi-periodic motion of the imaging object; producing a plurality of vectors based on the received list-mode data; generating a reference vector based on the produced plurality of vectors; selecting, from the produced plurality of vectors, a set of vectors corresponding to a single gate, based on respective differences compared with the generated reference vector; and generating an image of the imaging object based on the selected set of vectors.
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公开(公告)号：US20220113437A1
公开(公告)日：2022-04-14
申请号：US17557710
申请日：2021-12-21
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Evren ASMA , Xiaoli LI , Li YANG , Peng PENG , Jeffrey KOLTHAMMER
IPC: G01T1/29
Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.
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公开(公告)号：US20240037814A1
公开(公告)日：2024-02-01
申请号：US17878413
申请日：2022-08-01
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Chung CHAN , Li YANG , Xiaoli LI , Wenyuan QI , Evren ASMA , Jeffrey KOLTHAMMER
IPC: G06T11/00
CPC classification number: G06T11/005 , G06T2211/412
Abstract: A dynamic frame reconstruction apparatus and method for medical image processing is disclosed which reduces the computationally expensive reconstruction of images but which retains the accuracy of the image reconstruction. A convolutional neural network is used to cluster the dynamic data into groups of frames, each group sharing similar radiotracer distribution. In one embodiment, groups of frames that have similar reconstruction parameters are determined, and scatter and random estimations are computed once and shared among each of the frames in the same frame group.
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公开(公告)号：US20230342914A1
公开(公告)日：2023-10-26
申请号：US17726070
申请日：2022-04-21
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Karthikayan BALAKRISHNAN , Kent C. BURR , Manabu TESHIGAWARA , Jeffrey KOLTHAMMER , Wenyuan QI
CPC classification number: G06T7/0012 , G06T7/20 , G06T11/008 , G06T2207/10104 , G06T2207/20084 , G06T2207/10048
Abstract: A method of generating an image, including: receiving, via a monitoring device, time-dependent data corresponding to a patient parameter; obtaining emission data representing radiation detected during a medical imaging scan; identifying time frames during the medical imaging scan to exclude from the obtained emission data, the identified time frames corresponding to a stressed emotional state for the patient based on the patient parameter; modifying the obtained emission data to exclude the emission data corresponding to the time frames corresponding to the stressed emotional state; and generating an emotional-state-corrected image based on the modified emission data excluding the emission data corresponding to the time frames corresponding to the stressed emotional state.
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Patent Agency Ranking
公开(公告)号：US20220327665A1
公开(公告)日：2022-10-13
申请号：US17225672
申请日：2021-04-08
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Chung CHAN , Li YANG , Wenyuan Ql , Evren ASMA , Jeffrey KOLTHAMMER , Yi QIANG
Abstract: Existing, low quality images can be restored using reconstruction or a combination of post-reconstruction techniques to generate a real patient phantom. The real patient phantom (RPP) can then be simulated in Monte Carlo simulations of a higher performance system and a lower performance system. Alternatively, the RPP can be simulated in the higher performance system, and a real scan can be performed by an existing, lower performance system. The higher performance system can be differentiated from the lower performance system in a variety of ways, including a higher resolution time of flight measurement capability, a greater sensitivity, smaller detector crystals, or less scattering. A neural network can be trained using the images produce by the higher performance system as the target, and the images produced by the lower performance system as the input. After training, the trained neural network can be used to output input images taken in a lower performance system with higher performance system characteristics.
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7.发明申请公开(公告)号：US20230026719A1
公开(公告)日：2023-01-26
申请号：US17469144
申请日：2021-09-08
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Chung CHAN , Junyu CHEN , Evren ASMA , Jeffrey KOLTHAMMER
IPC: G06N3/08 , G06N3/04 , G06V10/771 , G06V10/82
Abstract: A neural network is initially trained to remove errors and is later fine tuned to remove less-effective portions (e.g., kernels) from the initially trained network and replace them with further trained portions (e.g., kernels) trained with data after the initial training.
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公开(公告)号：US20220395246A1
公开(公告)日：2022-12-15
申请号：US17345716
申请日：2021-06-11
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yujie LU , Ryo OKUDA , Evren ASMA , Manabu TESHIGAWARA , Jeffrey KOLTHAMMER
Abstract: The present disclosure is related to removing scatter from a SPECT scan by utilizing a radiative transfer equation (RTE) method. An attenuation map and emission map are acquired for generating scatter sources maps and scatter on detectors using the RTE method. The estimated scatter on detectors can be removed to produce an image of a SPECT scan with less scatter. Both first-order and multiple-order scatter can be estimated and removed. Additionally, scatter caused by multiple tracers can be determined and removed.
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公开(公告)号：US20220335664A1
公开(公告)日：2022-10-20
申请号：US17230372
申请日：2021-04-14
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Peng PENG , Evren ASMA , Jeffrey KOLTHAMMER
Abstract: A guided pairing method includes generating a singles list by detecting a plurality of singles at a plurality of detector elements in a detector array, the plurality of singles falling within a plurality of detection windows; for each detection window of the plurality of detection windows in the singles list having exactly two singles of the plurality of singles, determining the line of responses (LORs) for each of the two singles of the plurality of singles; for each detection window of the plurality of detection windows in the singles list having more than two singles of the plurality of singles, determining all coincidences possible based on the more than two singles; generating a weight for said each coincidence of the coincidences based on the determined LORs for said each of the two singles of the plurality of singles; and pairing the more than two singles based on the generated weight for said each coincidence of the coincidences.
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公开(公告)号：US20210208293A1
公开(公告)日：2021-07-08
申请号：US16866993
申请日：2020-05-05
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Evren ASMA , Xiaoli LI , Li YANG , Peng PENG , Jeffrey KOLTHAMMER
IPC: G01T1/29
Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.
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