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公开(公告)号：US20220395246A1
公开(公告)日：2022-12-15
申请号：US17345716
申请日：2021-06-11
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yujie LU , Ryo OKUDA , Evren ASMA , Manabu TESHIGAWARA , Jeffrey KOLTHAMMER
Abstract: The present disclosure is related to removing scatter from a SPECT scan by utilizing a radiative transfer equation (RTE) method. An attenuation map and emission map are acquired for generating scatter sources maps and scatter on detectors using the RTE method. The estimated scatter on detectors can be removed to produce an image of a SPECT scan with less scatter. Both first-order and multiple-order scatter can be estimated and removed. Additionally, scatter caused by multiple tracers can be determined and removed.
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公开(公告)号：US20220335664A1
公开(公告)日：2022-10-20
申请号：US17230372
申请日：2021-04-14
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Peng PENG , Evren ASMA , Jeffrey KOLTHAMMER
Abstract: A guided pairing method includes generating a singles list by detecting a plurality of singles at a plurality of detector elements in a detector array, the plurality of singles falling within a plurality of detection windows; for each detection window of the plurality of detection windows in the singles list having exactly two singles of the plurality of singles, determining the line of responses (LORs) for each of the two singles of the plurality of singles; for each detection window of the plurality of detection windows in the singles list having more than two singles of the plurality of singles, determining all coincidences possible based on the more than two singles; generating a weight for said each coincidence of the coincidences based on the determined LORs for said each of the two singles of the plurality of singles; and pairing the more than two singles based on the generated weight for said each coincidence of the coincidences.
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公开(公告)号：US20210208293A1
公开(公告)日：2021-07-08
申请号：US16866993
申请日：2020-05-05
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Evren ASMA , Xiaoli LI , Li YANG , Peng PENG , Jeffrey KOLTHAMMER
IPC: G01T1/29
Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.
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公开(公告)号：US20240233213A1
公开(公告)日：2024-07-11
申请号：US18151497
申请日：2023-01-09
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Yi QIANG , Xiaohui ZHAN , Wenyuan QI , Jeffrey KOLTHAMMER
IPC: G06T11/00
CPC classification number: G06T11/008 , G06T2207/10104 , G06T2207/20084
Abstract: A method is provided for generating an attenuation map for PET image reconstruction. The method includes training a deep convolutional neural network (DCNN) model by minimizing a loss function between initial input image data and the attenuation map generated by a spectral CT scan as supervised data. Further, the method includes obtaining PET data from a scan of a subject and reconstructing a PET image from the PET data and an attenuation map output from the DCNN. The initial input image data can be from a conventional CT scan with or without beam-hardening correction or the input image data can be from a phantom, a simulation, or a SPECT image.
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5.发明公开公开(公告)号：US20240233211A1
公开(公告)日：2024-07-11
申请号：US18336741
申请日：2023-06-16
Inventor： Wenyuan QI , Li YANG , Jeffrey KOLTHAMMER , Evren ASMA , Jinyi QI , Tiantian LI
CPC classification number: G06T11/005 , A61B6/037 , A61B6/5288 , G06T7/20 , G06T2207/10104
Abstract: A method for signal separation includes obtaining list mode data representing radiation detected during an imaging scan, the list mode data being affected by quasi-periodic motion of an imaging object; dividing the list mode data into first non-overlapping frames of a first frame length, and process the first frames to determine a cardiac cycle length; determining a second frame length, longer than the first frame length, based on the determined cardiac cycle length; re-binning the list mode data into overlapping frames having the second frame length, based on the non-overlapping frames having the first frame length; applying a principal component analysis (PCA) process on the re-binned list mode data having the second frame length to determine a respiratory waveform; determining a cardiac waveform using the determined respiratory waveform; and reconstructing an image based on the list mode data using the determined respiratory waveform and the determined cardiac waveform.
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Patent Agency Ranking
公开(公告)号：US20240122558A1
公开(公告)日：2024-04-18
申请号：US17963737
申请日：2022-10-11
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Kent C. BURR , Yi QIANG , Evren ASMA , Jeffrey KOLTHAMMER
CPC classification number: A61B6/037 , A61B6/4258 , A61B6/481
Abstract: A PET scanner includes gamma-ray detector rings that form a bore through which an imaging subject is translated, a length of the bore defining an axial length of the PET scanner, the gamma-ray detector rings being movable along the axial length, the gamma-ray detector rings including gamma-ray detector modules therein, and processing circuitry configured to receive PET data associated with a plurality of transaxial slices of the imaging subject, the PET data including a first set of spatial information and timing information corresponding to a first data acquisition period for the gamma-ray detector modules in a first axial position and a second set of spatial information and timing information corresponding to a second data acquisition period for the gamma-ray detector modules in a second axial position, and reconstruct a PET image based on the first set of spatial and timing information and the second set of spatial and timing information.
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公开(公告)号：US20220343566A1
公开(公告)日：2022-10-27
申请号：US17237975
申请日：2021-04-22
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Peng PENG , Yi QIANG , Wenyuan QI , Xiaoli LI , Li YANG
Abstract: An apparatus for reconstructing a positron emission tomography (PET) image, comprising processing circuitry configured to extract, from raw data obtained from a PET scanner, energy data and timing data associated with a plurality of annihilation events, the extracted energy data and the extracted timing data for each annihilation event corresponding to interactions between each of a pair of gamma rays generated by each annihilation event and one or more gamma ray detectors of the PET scanner, classify each annihilation event based on respective extracted energy data and respective extracted timing data, determine, for each annihilation event and based on a calculated timing resolution of the annihilation event, a width of a time-of-flight kernel, and reconstruct, by processing circuitry, the PET image based on the obtained raw data from the PET scanner and the determined width of the time-of-flight kernel associated with each annihilation event.
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8.发明公开公开(公告)号：US20240225585A1
公开(公告)日：2024-07-11
申请号：US18336807
申请日：2023-06-16
Inventor： Wenyuan QI , Li YANG , Jeffrey KOLTHAMMER , Yu-Jung TSAI , Evren ASMA , Maria IATROU , Jinyi QI , Tiantian LI
Abstract: A method for performing single gating in a positron emission tomography (PET) system includes: receiving list-mode data acquired by scanning an imaging object using the PET system, the list-mode data being affected by quasi-periodic motion of the imaging object; producing a plurality of vectors based on the received list-mode data; generating a reference vector based on the produced plurality of vectors; selecting, from the produced plurality of vectors, a set of vectors corresponding to a single gate, based on respective differences compared with the generated reference vector; and generating an image of the imaging object based on the selected set of vectors.
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9.发明公开公开(公告)号：US20230260171A1
公开(公告)日：2023-08-17
申请号：US17674063
申请日：2022-02-17
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Qiang YI , Evren ASMA , Li YANG , Peng PENG
CPC classification number: G06T11/006 , A61B6/037 , A61B6/5282 , G01T1/2985 , G06T11/005 , G06T2211/421
Abstract: Upon receiving list-mode data by detecting radiation emitted from a radiation source positioned with a field of view of a medical imaging scanner, each photon included in the list-mode data can be classified according to one or more interaction properties, such as energy or number of crystals interacted with. Grouped pairs of photons can be generated based on the classifying, and a corresponding interaction-property-specific correction kernel (e.g., a corresponding interaction-property-specific point spread function correction kernel) can be selected for each group. Corresponding interaction-property-specific correction kernels can then be utilized to generate higher quality images.
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公开(公告)号：US20220113437A1
公开(公告)日：2022-04-14
申请号：US17557710
申请日：2021-12-21
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Wenyuan QI , Yi QIANG , Evren ASMA , Xiaoli LI , Li YANG , Peng PENG , Jeffrey KOLTHAMMER
IPC: G01T1/29
Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.
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