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公开(公告)号:US09717663B2
公开(公告)日:2017-08-01
申请号:US15224681
申请日:2016-08-01
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
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2.
公开(公告)号:US20160106643A1
公开(公告)日:2016-04-21
申请号:US14887774
申请日:2015-10-20
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable it 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than an other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
Abstract translation: 一种止汗活性组合物,其包含铝盐,所述铝盐(i)的铝与氯化物的摩尔比为0.3:1至3:1; 和(ii)具有聚羟基氧化铝阳离子的物质,其可通过27Al NMR检测到76ppm,其在27Al NMR光谱仪上的相对丰度存在,其大于可通过27Al NMR检测的其它聚羟基氧代铝阳离子。 此外,公开了使止汗剂活性的方法。
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公开(公告)号:US20170008773A1
公开(公告)日:2017-01-12
申请号:US15272357
申请日:2016-09-21
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , John Vaughn , Long Pan
CPC classification number: C01F7/56 , A61K8/26 , A61K8/28 , A61K8/44 , A61K2800/592 , A61K2800/80 , A61Q15/00 , C01F7/002 , C01P2002/86 , C01P2002/87
Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.
Abstract translation: 一种包含氯化铝水合物盐的组合物,该水合氯化铝盐具有至少50摩尔%的所有聚羟基氧化铝阳离子的Al30聚羟基氧化铝阳离子,其可通过在水合氯化铝盐内的定量27Al NMR和缓冲液检测。 该组合物可以任选地包括锆。 还公开了使用起始铝盐与缓冲剂的摩尔浓度增加的方法,用氯化铝水合物盐减少汗水的方法以及用氯化铝水盐处理水的方法。
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公开(公告)号:US20160266066A1
公开(公告)日:2016-09-15
申请号:US15036261
申请日:2013-11-12
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Long Pan , Shaotang Yuan , Iraklis Pappas , John Vaughn , James G. Masters
CPC classification number: G01N27/44782 , A61K8/19 , A61K8/26 , A61K8/27 , A61K8/28 , A61K8/44 , A61K2800/58 , A61K2800/74 , A61K2800/805 , A61Q15/00 , D06M13/005
Abstract: Methods of estimating the suitability of a candidate antiperspirant material by measuring the zeta potential of the material.
Abstract translation: 通过测量材料的ζ电位来估计候选止汗材料的适用性的方法。
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5.
公开(公告)号:US09408789B2
公开(公告)日:2016-08-09
申请号:US14887774
申请日:2015-10-20
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable it 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than an other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
Abstract translation: 一种止汗活性组合物,其包含铝盐,所述铝盐(i)的铝与氯化物的摩尔比为0.3:1至3:1; 和(ii)具有聚羟基氧化铝阳离子的物质,其可通过27Al NMR检测到76ppm,其在27Al NMR光谱仪上的相对丰度存在,其大于可通过27Al NMR检测的其它聚羟基氧代铝阳离子。 此外,公开了使止汗剂活性的方法。
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公开(公告)号:US10118832B2
公开(公告)日:2018-11-06
申请号:US15272357
申请日:2016-09-21
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , John Vaughn , Long Pan
Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.
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公开(公告)号:US20170128330A1
公开(公告)日:2017-05-11
申请号:US15224681
申请日:2016-08-01
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
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