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公开(公告)号:US09717663B2
公开(公告)日:2017-08-01
申请号:US15224681
申请日:2016-08-01
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
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2.
公开(公告)号:US20150328097A1
公开(公告)日:2015-11-19
申请号:US14807946
申请日:2015-07-24
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Long Pan
CPC classification number: C01F7/56 , A61K8/26 , A61K8/28 , A61K8/44 , A61K2800/592 , A61K2800/80 , A61Q15/00 , C01F7/002 , C01P2002/86 , C01P2002/87
Abstract: A method of making an antiperspirant active composition and the use of a heating step at elevated temperature to convert Al13 polyhydroxyoxoaluminum cations in the species detectable by 27Al NMR within an aqueous aluminum salt solution into Al30 polyhydroxyoxoaluminum cations in the species detectable by 27Al NMR without increasing a SEC Peak 3 area in the SEC chromatogram of the aluminum salt.
Abstract translation: 一种制备止汗活性组合物的方法和在升高的温度下使用加热步骤将AlI 3聚羟基氧化铝阳离子在AlAlO盐溶液中通过27Al NMR转化成可通过27Al NMR检测的物质中的Al30聚羟基氧化铝阳离子,而不增加 SEC铝盐的SEC色谱图中的峰3区。
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公开(公告)号:US11253449B2
公开(公告)日:2022-02-22
申请号:US16720071
申请日:2019-12-19
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Zhichao Hu , Donghui Wu
Abstract: An oral care composition comprising primarily insoluble forms of zinc compounds and stannous compounds, as well as methods of using the same in the treatment or prevention of gingivitis, plaque, and dental caries.
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公开(公告)号:US20210158905A1
公开(公告)日:2021-05-27
申请号:US17247166
申请日:2020-12-02
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
Abstract: A system, apparatus, and/or method is disclosed for producing a personal care product. An identity of a considered chemical composition may be input into a model (e.g., a machine learning model). The identity of the considered chemical composition may include ingredients. Each of the ingredients of the considered chemical composition may be associated with a value of a chemoinformatic property of chemoinformatic properties of the considered chemical composition. A value of the property of the considered chemical composition may be determined via the model. The value may be based on the identity of the considered chemical composition. The property of the considered chemical composition may be affected by an interaction of at least two of the ingredients of the considered chemical composition. A personal care product comprised of the considered chemical composition may be produced.
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公开(公告)号:US09872826B2
公开(公告)日:2018-01-23
申请号:US14648359
申请日:2012-12-03
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Jason Nesta , Shira Pilch
CPC classification number: A61K8/73 , A61K8/042 , A61K8/20 , A61Q11/00 , C08B37/006 , C08J3/075 , C08J3/24 , C08J2305/00 , C08L5/00
Abstract: Disclosed is a method of manufacturing a fluid gel, the method comprising adding metal cations to the gellant dispersion while retaining the pH at no greater than 3; and adding a pH modifying agent to the gellant dispersion to increase the pH of the gellant dispersion to greater than 3.
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6.
公开(公告)号:US09408789B2
公开(公告)日:2016-08-09
申请号:US14887774
申请日:2015-10-20
Applicant: Colgate-Palmolive Company
Inventor: John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable it 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than an other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
Abstract translation: 一种止汗活性组合物,其包含铝盐,所述铝盐(i)的铝与氯化物的摩尔比为0.3:1至3:1; 和(ii)具有聚羟基氧化铝阳离子的物质,其可通过27Al NMR检测到76ppm,其在27Al NMR光谱仪上的相对丰度存在,其大于可通过27Al NMR检测的其它聚羟基氧代铝阳离子。 此外,公开了使止汗剂活性的方法。
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公开(公告)号:US20140314701A1
公开(公告)日:2014-10-23
申请号:US14321893
申请日:2014-07-02
Applicant: Colgate-Palmolive Company
Inventor: Long Pan , Donghui Wu , LaTonya Kilpatrick-Liverman , Michael Fitzgerald , Matthew J. Eibling , Iraklis Pappas
CPC classification number: A61K8/416 , A61K8/26 , A61K8/42 , A61K8/44 , A61K2800/31 , A61K2800/58 , A61Q15/00
Abstract: An anhydrous liquid antiperspirant composition comprising a carrier comprising a cation and/or zwitterion and a hydrogen bond donor, wherein an amount of carrier is greater than an amount of any other material in the composition, and an antiperspirant active. This represents a new delivery form for antiperspirant actives and/or deodorant actives.
Abstract translation: 一种包含阳离子和/或两性离子和氢键供体的载体的无水液体止汗组合物,其中载体的量大于组合物中任何其它物质的量,以及止汗活性剂。 这代表了止汗活性物质和/或除臭活性物质的新的交付形式。
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公开(公告)号:US20250029060A1
公开(公告)日:2025-01-23
申请号:US18910396
申请日:2024-10-09
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Junfang Katy Qian-Pena , Keeyan Haghshenas , John Wolf , Michael Fitzgerald , Evan Wireman
IPC: G06Q10/101
Abstract: In one embodiment, the present disclosure is directed to a method for producing a product. For each sample chemical composition of sample chemical compositions, the method inputs into a first model chemoinformatic properties of ingredients of the sample chemical composition, and a value of a property of the sample chemical composition. A new chemical composition is determined via the first model based thereon. The method inputs into a second model, for each sample product of sample products, a value for one or more visual properties of a packaging of the sample product, and one or more characteristics of the new chemical composition. A value is determined for each of the visual properties via the second model. A new product is produced comprising the new chemical composition and packaging comprising the values.
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公开(公告)号:US11378529B2
公开(公告)日:2022-07-05
申请号:US17137039
申请日:2020-12-29
Applicant: Colgate-Palmolive Company , Northwestern University
Inventor: Michael Fitzgerald , Iraklis Pappas , Jean-Francois Gaillard , Marco Alsina Corvalan
IPC: G01N23/083 , G01N21/89 , G01N21/94 , G01N23/087
Abstract: The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content.
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公开(公告)号:US11342049B2
公开(公告)日:2022-05-24
申请号:US17247166
申请日:2020-12-02
Applicant: Colgate-Palmolive Company
Inventor: Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
Abstract: A system, apparatus, and/or method is disclosed for producing a personal care product. An identity of a considered chemical composition may be input into a model (e.g., a machine learning model). The identity of the considered chemical composition may include ingredients. Each of the ingredients of the considered chemical composition may be associated with a value of a chemoinformatic property of chemoinformatic properties of the considered chemical composition. A value of the property of the considered chemical composition may be determined via the model. The value may be based on the identity of the considered chemical composition. The property of the considered chemical composition may be affected by an interaction of at least two of the ingredients of the considered chemical composition. A personal care product comprised of the considered chemical composition may be produced.
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